Safety and effectiveness of bemiparine in the prevention of venous thromboembolic disease in nursing home patients;Eficacia y seguridad de bemiparina en la prevención de la enfermedad tromboembólica venosa en pacientes de una residencia geriátrica

Revista Espanola de Geriatria y Gerontologia

Volumn 42, Issue 1, 2007, Pages 20-26

  Prieto Seva, Álvaro José ^a  

^a Residencia de Tercera Edad Alacant   (Spain)

Author keywords

Bemiparine; Effectiveness; Pharmacovigilance; Safety; The elderly; Venous thromboembolic disease

Indexed keywords

BEMIPARIN;

ARTICLE; BLOOD CLOTTING; BONE DENSITOMETRY; CLINICAL ARTICLE; COMORBIDITY; DOPPLER ECHOGRAPHY; DRUG EFFICACY; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; DRUG WITHDRAWAL; GERIATRIC PATIENT; HEMATOMA; HIGH RISK POPULATION; HUMAN; IMMOBILIZATION; INJECTION SITE PAIN; KIDNEY FUNCTION; NURSING HOME PATIENT; OBSERVATIONAL STUDY; PROSPECTIVE STUDY; QUALITY OF LIFE; RISK FACTOR; THROMBOCYTE COUNT; TREATMENT DURATION; TREATMENT OUTCOME; VENOUS THROMBOEMBOLISM;

EID: 33947700479     PISSN: 0211139X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0211-139X(07)73517-5     Document Type: Article

References (25)

1. Fernández Sánchez J, Buecklein W. Trombosis venosa profunda de la extremidad inferior en pacientes geriátricos. Geriatrika. 2000;16:280-6.
2. Miralles Basseda R. Vasculopatías periféricas. En: Reuss JM, editor. Manual de Medicina Geriátrica en Residencias. Madrid: EDIMSA; 2000. p. 321-35.
3. Dahan R, Houlbert D, Caulin C, Cuzin E. Prevention of deep vein thrombosis in elderly medical patients by a low molecular weight heparine: a randomized double blind trial. Haemostasis. 1986;16:159-64.
4. Forette B, Wolmark Y. Calcium nadroparine in the prevention of thromboembolism disease subjects. Study of tolerance. Press Med. 1995;24:567-71.
5. Bergmann JF, Neuhart E. A multicenter randomized double blind study of enoxaparine compared with unfractioned heparin in the prevention of venous thromboembolism disease in elderly inpatients bedridden for an acute medical illness. The enoxaparine in medicine Study Group. Thromb Haemost. 1996;76:529-34.
6. Fenollosa J, Seminario P. Eficacia y seguridad de bemiparina en la profilaxis del tromboembolismo venoso en cirugía ortopédica. Rev Ortoped Traumalol. 2001;45:460-5.
7. Merkel D, Zippel C, Rech P. Low molecular weight heparins after orthopaedic and traumatologic operations in geriatrics. Z Gerontol Geriatr. 2002;35:54-9.
8. Harenberg J, Huhle G, Piazolo L, Giese C, Heene DL. Long term anticoagulation of outpatients with adverse events to oral anticoagulants using low molecular weight heparin. Semin Thromb Haemost. 1997;23:167-72.
9. Álvarez Nebreda ML, Pérez Tamayo I, Brañas Baztan F, Rada Martínez S, Serra Rexach JA, González Ramallo V, et al. Tratamiento de la trombosis venosa profunda en pacientes mayores de 60 años en una unidad de hospitalización a domicilio. Rev Esp Geriatr Gerontol. 2002;37:254-9.
10. Honorato J, Gomez Outes A, Navarro Quilis A, Martinez Gonzalez J, Rochea E, Planes A. Pharmacoeconomic analysis of bemiparin and enoxaparin as prophylaxis for venous thromboembolism in total knee replacement surgery. Pharmacoeconomics. 2004;22:885-94.
11. Fernández Pavón A. Características fisicoquímicas y farmacológicas, mecanismos de acción y diferencias con la heparina no fraccionada. En: Rocha, Díaz Sánchez, Alegría, editores. Heparinas de Bajo Peso Molecular. Madrid: Pharmacia; 2002.
12. Belmin J, Medjahed S, Trivalle C, Lutzler P. Groupe de Reserche sur l'héparine en Gériatrie (GRENG). Press Med. 2001;30:101-6.
13. Di Minno G, Tufano A, Cerbone AM. Antithrombotic drugs for older subjects. Guidelines formulated jointly by the Italian Societies of Haemostasis and Thrombosis (SISET) and of Gerontology and Geriatrics (SIGG). Nutr Metab Cardiovasc Dis. 2001;11:41-62.
14. McCarthy JE, O'Donell J. Prophylaxis of venous thromboembolism in Irish hospitals. Ir Med J. 1993;86:199-202.
15. Gomes JF, Shaheemn WH, Troung SV, Brown EF, Beaslley SW, Gajewski BJ. Incidence of venous thromboembolism events among nursing home residents. J Gen Intern Med. 2003;18:934-6.
16. Gatt ME, Paltiel O, Bursztyn M. Is prolonged immobilization a risk factor for symptomatic venous thromboembolism in elderly bedridden patients? Results of a historical-cohort study. Thromb Haemost. 2004;91:538-43.
17. Kakkar W, Howes J, Sharma V, Kadziola Z. A comparative double blind randomised trial of a new second generation LMWH (bemiparin) and UFH in the prevention of postoperative venous thromboembolism. The bemiparine assesment group. Thromb Haemost. 2000;83:523-9.
18. Planes A, Vochelle N, Gonzalez de Suso MJ, Claracq JP. Profilaxis antitrombótica poscirugía ortopédica con bemiparina, heparina de bajo peso molecular de segunda generación. Rev Esp Anestesiol Reanim. 2001;48:258-63.
19. Wawrzyska L, Tomkowski WZ, Przedlacki J, Hajduk B, Torbicki A. Changes in bone density during long-term administration of low-molecular-weight heparins or acenocoumarol for secondary prophylaxis of venous thromboembolism. Pathophysiol Haemost Thromb. 2003;33:64-7.
20. Planes A. Review of bemiparin sodium - a new second generation low molecular weight heparin and its applications in venous thromboembolism. Expert Opin Pharmacother. 2003;4:1551-61.
21. Chapman TM, Goa KL. Bemiparin: a review of its use in the prevention of venous thromboembolism and treatment of deep vein thrombosis. Drugs. 2003;63:2357-77.
22. Navarro-Quilis A, Castellet E, Rocha E, Paz Jiménez J, Planes A. Efficacy and safety of bemiparin compared with enoxaparin in the prevention of venous thromboembolism after total knee arthroplasty: a randomized, double blind clinical trial. J Thromb Haemost. 2003;1:425-32.
23. Depasse F, Gonzalez de Suso MJ, Lagoutte I, Fontcuberta J, Borrell M, Samama MM. Comparative study of the pharmacokinetics profile of two LMWHs-bemiparin (3500 IU anti Xa) and tinzaparin (4500 IU anti Xa) - administered subcutaneously to healthy male volunteers. Thromb Res. 2003;3:109-17.
24. Ackermann RJ. Nursing home practice. Strategies to manage most acute and chronic illnesses without hospitalization. Geriatrics. 2001;56:37-44.
25. Prieto Seva AJ. Asistencia sociosanitaria: revisión y reflexiones. Geriatrika. 2002;18:27-39.