Cellulose esters in drug delivery

Cellulose

Volumn 14, Issue 1, 2007, Pages 49-64

  Edgar, Kevin J ^a  

^a EASTMAN CHEMICAL COMPANY   (United States)

Author keywords

Amorphous matrix; Cellulose acetate; Cellulose acetate butyrate; Cellulose acetate phthalate; Cellulose acetate propionate; Cellulose ester; Controlled release; Drug delivery; Enteric coating; Matrix release; Osmotic pump; Zero order release

Indexed keywords

CELLULOSE; DRUG PRODUCTS; ESTERS; MECHANICAL PERMEABILITY; NANOPARTICLES; TOXICITY;

CELLULOSE ACETATE; CELLULOSE ACETATE BUTYRATE; CELLULOSE ACETATE PHTHALATE; CELLULOSE ACETATE PROPIONATE; CELLULOSE ESTERS;

CONTROLLED DRUG DELIVERY;

CELLULOSE ACETATE; DRUG DELIVERY; PERMEABILITY; TOXICITY;

EID: 33947657411     PISSN: 09690239     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10570-006-9087-7     Document Type: Article

References (66)

1. Appel L.E., Curatolo W.J., Herbig S.M., Nightingale J.A.S., Thombre A.G. (2004). Controlled release by extrusion of solid amorphous dispersions of drugs. US Patent 6:706, 283
2. Bauer C.W., Masucci P.E. (1948). The action of intestinal enzymes upon cellulose acetate phthalate and butyl stearate enteric-coated tablets. J. Am. Pharm. Assoc. 37:124-128
3. Beyger J.W., Nairn J.G. (1986). Some factors affecting the microencapsulation of pharmaceuticals with cellulose acetate phthalate. J. Pharm. Sci. 75:573-578
4. Bhardwaj S.B., Shukla A.J., Collins C.C. (1995). Effect of varying drug loading on particle size distribution and drug release kinetics of verapamil hydrochloride microspheres prepared with cellulose esters. J. Microencapsul. 12:71-81
5. Carino G.P., Jacob J.S., Mathiowitz E. (2000). Nanosphere based oral insulin delivery. J. Contr. Rel. 65:261-269
6. Catellani P.L., Colombo P., Peppas N.A., Santi P., Bettini R. (1998). Partial permselective coating adds an osmotic contribution to drug release from swellable matrixes. J. Pharm. Sci. 87:726-731
7. Chang R.-K., Price J. and Whitworth C.W. 1986. Control of drug release rates through the use of mixtures of polycaprolactone and cellulose propionate polymers. Pharm. Tech. October: 24-33
8. Chang R.-K., Price J., Whitworth C.W. (1987). Control of drug release rate by use of mixtures of polycaprolactone and cellulose acetate butyrate polymers. Drug Dev. Ind. Pharm. 13:1119-1135
9. Cohen J. (2005). Gut assumes sinister new role in HIV pathogenesis. Science 307:1395
10. Curatolo W.J., Nightingale J.A.S., Shanker R.M. and Sutton S.C. 2003. Basic drug compositions with enhanced bioavailability. US Patent 6,548,555
11. Davis S.S. (2005). Formulation strategies for absorption windows. Drug Del. Tech. 10:249-257
12. Efentakis M., Koutlis A. and Vlachou M. 2000. Development and evaluation of oral multiple unit and single-unit hydrophilic controlled release systems. AAPS PharmSciTech 1: Article 34
13. El-Gibaly I., Safwat S.M., Ahmed M.O. (1996). Microencapsulation of ketoprofen using w/o/w complex emulsion technique. J. Microencapsul. 13:67-97
14. El-Said Y., Hashem F. (1991). In-vitro evaluation of sustained-release dyphylline tablets. Drug Dev. Ind. Pharm. 17:281-293
15. Evans D.F., Pye G., Bramley R., Clark A.G., Tyson T.J., Hardcastle J.D. (1988). Measurement of gastrointestinal pH profiles in normal ambulant human subjects. Gut 29:1035-1041
16. Follonier N., Doelker E. (1992). Biopharmaceutical comparison of oral multiple-unit and single-unit sustained-release dosage forms. S.T.P. Pharm. Sci. 2:141-158
17. Giunchedi P., Conti B., Maggi L., Conte U. (1994). Cellulose acetate butyrate and polycaprolactone for ketoprofen spray-dried microsphere preparation. J. Microencapsul. 11:381-393
18. Jacobsen O., Højgaard L., Møller E.H., Wielandt T.O., Thale M., Jarnum S., Krag E. (1985). Effect of enterocoated cholestyramine on bowel habit after ileal resection: A double blind crossover study. Brit. Med. J. 290:1315-1318
19. Kashdan D.S. 1989. Polymer blends having reverse phase morphology for controlled delivery of bioactive agents. US Patent 4,795,641
20. Klausner E.A., Lavy E., Friedman M., Hoffman A. (2003). Expandable gastroretentive dosage forms. J. Contr. Rel. 90:143-162
21. Kojima M., Nakagami H. (2002). Development of controlled release matrix pellets by annealing with micronized water-insoluble or enteric polymers. J. Contr. Rel. 82:335-343
22. Kuo C.M., Curtis L.G. and Lucas P.L. 1994. Aqueous dispersion useful in coatings containing hydrolyzed cellulose ester and acrylic resin. US Patent 5,334,638
23. Leuner C., Dressman J. (2000). Improving drug solubility for oral delivery using solid dispersions. Eur. J. Pharm. Biopharm. 50:47-60
24. Levine D.S., Raisys V.A., Ainardi V. (1987). Coating of oral beclomethasone dipropionate capsules with cellulose acetate phthalate enhances delivery of topically active anti-inflammatory drug to the terminal ileum. Gastroenterology 92:1037-1044
25. Liu J., Chan S.Y., Ho P.C. (2002). Polymer-coated microparticles for the sustained release of nitrofurantoin. J. Pharm. Pharmacol. 54:1205-1212
26. Lyu S.-P., Sparer R., Hobot C., Dang K. (2005). Adjusting drug diffusivity using miscible polymer blends. J. Contr. Rel. 102:679-687
27. Makhija S.N., Vavia P.R. (2003). Controlled porosity osmotic pump-based controlled release systems of pseudoephedrine. I. Cellulose acetate as a semipermeable membrane. J. Contr. Rel. 89:5-18
28. Malm C.J., Emerson J., Hiatt G.D. (1951). Cellulose acetate phthalate as an enteric coating material. J. Am. Pharm. Assoc. 40:520-525
29. Malm C.J., Fordyce C.R. (1940). Cellulose esters of dibasic organic acids. Ind. Eng. Chem. 32:405-408
30. Malm C.J., Mench J.W., Fulkerson B., Hiatt G.D. (1957). Preparation of phthalic acid esters of cellulose. Ind. Eng. Chem. 49:84-88
31. Mathiowitz E., Jacob J.S., Jong Y.S., Carino G.P., Chickering D.E., Chaturvedi P., Santos C.A., Vijayaraghavan K., Montgomery S., Bassett M., Morrell C. (1997). Biologically erodable microspheres as potential oral drug delivery systems. Nature 386:410-414
32. Moretti M.D.L., Gavini E., Juliano C., Pirisino G., Giunchedi P. (2001). Spray-dried microspheres containing ketoprofen formulated into capsules and tablets. J. Microencapsul. 18: 111-121
33. Nokhodchi A. and Farid D. 2002. Microencapsulation of paracetamol by various emulsion techniques using cellulose acetate phthalate. Pharm. Tech. 54-60
34. Obeidat W.M., Price J.C. (2003). Viscosity of polymer solution phase and other factors controlling the dissolution of theophylline microspheres prepared by the emulsion solvent evaporation method. J. Microencapsul. 20:57-65
35. Obeidat W.M., Price J.C. (2004). Evaluation of enteric matrix microspheres prepared by emulsion-solvent evaporation using scanning electron microscopy. J. Microencapsul. 21: 47-57
36. Omidian H., Rocca J.G., Park K. (2005). Advances in superporous hydrogels. J. Contr. Rel. 102:3-12
37. Palmieri G.F., Bonacucina G., Di Martino P., Martelli S. (2002). Gastro-resistant microspheres containing ketoprofen. J. Microencapsul. 19:111-119
38. Palmieri G.F., Michelini S., Di Martino P., Martelli S. (2000). Polymers with pH-dependent solubility: Possibility of use in the formulation of gastroresistant and controlled-release matrix tablets. Drug Dev. Ind. Pharm. 26: 837-845
39. Pongpaibul Y., Whitworth C.W. (1986a). Microencapsulation by emulsion non-solvent addition method. Drug Dev. Ind. Pharm. 12: 2387-2402
40. Pongpaibul Y., Whitworth C.W. (1986b). Preparation and in vitro dissolution characteristics of propranolol microcapsules. Int. J. Pharm. 33: 243-248
41. Prapaitrakul W., Whitworth C.W. (1989). Microencapsulation of phenylpropanolamine to achieve sustained release. J. Microencapsul. 6: 213-218
42. Santus G., Baker R.W. (1995). Osmotic drug delivery: A review of the patent literature. J. Contr. Rel. 35: 1-21
43. Sarisuta N., Kumpugdee M., Müller B.W., Puttipipatkhachorn S. (1999). Physico-chemical characterization of interactions between erythromycin and various film polymers. Int. J. Pharm. 186: 109-118
44. Schultz P., Kleinebudde P. (1997). A new multiparticulate delayed release system. Part I: Dissolution properties and release mechanism. J. Contr. Rel. 47:181-189
45. Sertsou G., Butler J., Scott A., Hempenstall J., Rades T. (2002). Factors affecting incorporation of drug into solid solution with HPMCP during solvent change co-precipitation. Int. J. Pharm. 245:99-108
46. Shukla A.J., Price J.C. (1991). Effect of drug loading and molecular weight of cellulose acetate propionate on the release characteristics of theophylline microspheres. Pharm. Res. 8:1396-1400
47. Singhal D., Curatolo W. (2004). Drug polymorphism and dosage form design: A practical perspective. Adv. Drug Del. Rev. 56: 335-347
48. Soppimath K.S., Kulkarni A.R., Aminabhavi T.M. (2001). Development of hollow microspheres as floating controlled-release systems for cardiovascular drugs: Preparation and release characteristics. Drug Devel. Ind. Pharm. 27: 507-515
49. Sprockel O.L., Prapaitrakul W. (1990). A comparison of microencapsulation by various emulsion techniques. Int. J. Pharm. 58: 123-127
50. Sprockel O.L., Prapaitrakul W., Shivanand P. (1990). Permeability of cellulose polymers: Water vapor transmission rates. J. Pharm. Pharmacol. 42: 152-157
51. Sprockel O.L., Price J.C. (1989). Evaluation of sustained release aqueous suspensions containing microencapsulated drug-resin complexes. Drug Dev. Ind. Pharm. 15: 1275-1287
52. Stithit S., Chen W., Price J.C. (1998). Development and characterization of buoyant theophylline microspheres with near zero order release kinetics. J. Microencapsul. 15: 725-737
53. Tanno F., Nishiyama Y., Kokubo H., Obara S. (2004). Evaluation of hypromellose acetate succinate (HPMCAS) as a carrier in solid dispersions. Drug Dev. Ind. Pharm. 30: 9-17
54. Theeuwes F. (1975). Elementary osmotic pump. J. Pharm. Sci. 64:1987-1991
55. Theeuwes F. (1983). Oros® osmotic system development. Drug Dev. Ind. Pharm. 9:1331-1357
56. Thoma K., Bechtold K. (1999). Influence of aqueous coatings on the stability of enteric coated pellets and tablets. Eur. J. Pharm. Biopharm. 47: 39-50
57. Vaithiyalingam S., Reddy I.K., Khan M.A., Guven N. (2001). Aqueous-based cellulose acetate butyrate dispersion: Screening of process and formulation variables to obtain verapamil HCl-controlled release tablets. Part. Sci. Tech. 19: 131-144
58. Vazquez-Torres H., Cruz-Ramos C.A. (1994). Blends of cellulose esters with poly(caprolactone): Characterization by DSC, DMA and WAXS. J. Appl. Poly. Sci. 54: 1141-1159
59. Verma R.K., Mishra B., Garg S. (2000). Osmotically controlled oral drug delivery. Drug Dev. Ind. Pharm. 26:695-708
60. Watts P.J., Illum L. (1997). Colonic drug delivery. Drug Dev. Ind. Pharm. 23: 893-913
61. Wilson A.K., Posey-Dowty J. and Kelley S.S. 1996a. Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends. US Patent 5,536,505
62. Wilson A.K., Posey-Dowty J. and Kelley S.S. 1996b. Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends. US Patent 5,523,095
63. Wu C.Y., Benet L.Z. (2005). Predicting drug disposition via application of BCS: Transport/absorption/elimination interplay and development of a biopharmaceutics drug disposition classification system. Pharm. Res. 22: 11-23
64. Wu S.H.W., Wyatt D.M., Adams M.W. (1997). Chemistry and applications of cellulosic polymers for enteric coatings of solid dosage forms. In: McGinity J.W. (ed) Aqueous Coatings for Pharmaceutical Dosage Forms. Marcel Dekker, New York, pp. 385-418
65. Xu X., Lee P.I. (1993). Programmable drug delivery from an erodible association polymer system. Pharm. Res. 10: 1144-1152
66. Yang M., Cui F., You B., You J., Wang L., Zhang L., Kawashima Y. (2004). A novel pH-dependent gradient release delivery system for nitrendipine I. Manufacturing, evaluation in vitro and bioavailability in healthy dogs. J. Contr. Rel. 98: 219-229