Increased inflammatory markers and endothelial dysfunction are associated with variant angina

Korean Circulation Journal

Volumn 37, Issue 1, 2007, Pages 27-32

  Sook, Hee Cho ^a   In, Hyae Park ^b   Myung, Ho Jeong ^a,b   Seon, Ho Hwang ^a   Nam, Shik Yun ^a   Seo, Na Hong ^a   Sang, Rok Lee ^a   Kye, Hun Kim ^a   Jae, Yun Moon ^a   Young, Joon Hong ^a   Hyung, Wook Park ^a,b   Ju, Han Kim ^a   Young, Keun Ahn ^a,b   Jeong, Gwan Cho ^a,b   Jong, Chun Park ^a,b   Jung, Chaee Kang ^a,b  

^a Chonnam National University Medical School   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Angina pectoris; Endothelium; Inflammation

Indexed keywords

C REACTIVE PROTEIN; HOMOCYSTEINE; NITRATE; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; ENDOTHELIAL DYSFUNCTION; FEMALE; HUMAN; INFLAMMATION; LABORATORY DIAGNOSIS; MALE; VARIANT ANGINA PECTORIS;

EID: 33947651258     PISSN: 17385520     EISSN: 17385555     Source Type: Journal    
DOI: 10.4070/kcj.2007.37.1.27     Document Type: Article

References (30)

1. Zipes DP, Libby P, Bonow RO, Braunwald E. Braunwald's Heart Disease. 7th ed. Philadelphia: WB Saunders; 2005. p.1264-7.
2. Kang JA, Lee YS, Jeong SH, et al. Clinical characteristics of patients with variant angina. Korean J Med 2002;63:195-202.
3. Jeong MH, Park JC, Rhew JY, et al. Successful management of intractable coronary spasm with a coronary stent. Jpn Circ J 2000;64:897-900.
4. Yasue H, Kugiyama K. Coronary spasm: clinical features and pathogenesis. Intern Med 1997;36:760-5.
5. Yamagishi M, Terashima M, Awano K, et al. Morphology of vulnerable coronary plaque: insights from follow-up of patients examined by intravascular ultrasound before an acute coronary syndrome. J Am Coll Cardiol 2000;35:106-11.
6. Saito S, Yamagishi M, Takayama T, et al. Plaque morphology at coronary sites with focal spasm in variant angina: study using intravascular ultrasound. Circ J 2003;67:1041-5.
7. Lee GR, Bithell TC, Foerster J. Wintrobe's Clinical Hematology. 9th ed. Philadelphia: Lea & Febriger; 1993. p.575-7.
8. Roldan V, Marin F, Garcia-Herola A, Lip GY. Correlation of plasma von Willebrand factor levels, an index of endothelial damage/dysfunction, with two point-based stroke risk stratification scores in atrial fibrillation. Thromb Res 2005;116:321-5.
9. Fowkes FG, Lowe GD, Housely E, et al. Cross linked fibrin degradation products, progression of peripheral arterial disease, and risk of coronary heart disease. Lancet 1993;342:84-6.
10. Celermajer DS, Sorensen KE, Gooch VM, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992;340:1111-5.
11. Hung MJ, Cherng WJ, Cheng CW, Li LF. Comparison of serum levels of inflammatory markers in patients with coronary vasospasm without significant fixed coronary artery disease versus patients with stable angina pectoris and acute coronary syndromes with significant fixed coronary artery disease. Am J Cardiol 2006;97:1429-34.
12. Maseri A, Severi S, Nes MD, et al. Variant angina: one aspect of a continuous spectrum of vasospastic myocardial ischemia: pathologenetic mechanisms, estimated incidence and clinical and coronary arteriographic findings in 138 patients. Am J Cardiol 1978;42:1019-35.
13. Chahine RA, Raizner AE, Ishimori T, Luchin RJ, McIntosh HD. The incidence and clinical implications of coronary arterty spasm. Circulation 1975;52:972-8.
14. Yasue H, Omote S, Takizawa A, Nagao M, Miwa K, Tanaka S. Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm. Circulation 1979;59:938-48.
15. Kugiyama K, Yasue H, Okumura K, et al. Nitric oxide activity is deficient in spasm arteries of patients with coronary spastic angina. Circulation 1996;94:266-71.
16. Teragawa H, Kato M, Kurokawa J, Yamagata T, Matsuura H, Chayama K. Endothelial dysfunction is an independent factor responsible for vasospastic angina. Clin Sci 2001;101:707-13.
17. Yamamoto H. Preserved endothelial function in the spastic segment of the human epicardial coronary artery in patients with variant angina: role of substance P in evaluating endothelial function. Eur Heart J 1993;14 (Suppl I): 118-22.
18. Botker HE, Sonne HS, Sorensen KE. Frequency of systemic microvascular dysfunction in syndrome X and in variant angina. Am J Cardiol 1996;78:182-6.
19. Motoyama T, Kawano H, Kugiyama K, et al. Flow-mediated, endothelium-dependent dilation of the brachial arteries is impaired in patients with coronary spastic angina. Am Heart J 1997; 133:263-7.
20. Motoyama T, Kawano H, Kugiyama K, et al. Vitamin E administration improves impairment of endothelium-dependent vasodilation in patients with coronary spastic angina. J Am Coll Cardiol 1998;32:1672-9.
21. Hirashima O, Kawano H, Motoyama T, et al. Improvement of endothelial function and insulin sensitivity with vitamin C in patients with coronary spastic angina: possible role of reactive oxygen species. J Am Coll Cardiol 2000;35:1860-6.
22. Choi MJ, Lee YS, Choi JS, et al. The clinical significance of smoking in Korean patients with variant angina. J Korean Soc Hypertension 2004;10:8-14.
23. Han KI, Han KH, Park SW, et al. The vasomotor tone in vasospastic angina. Korean Circ J 1991;21:889-96.
24. Kim NH, Jeong JW, Park EM, et al. Alterations of autonomic nervous activity associated with spontaneous coronary spasm in patients with variant angina. Korean Circ J 2004;34:362-7.
25. Libby P, Ridker PM. Inflammation and atherosclerosis: role of C-reactive protein in risk assessment. Am J Med 2004;116;9S-16S.
26. Devaraj S, Kumaresan PR, Jialal I. Effect of C-reactive protein on chemokine expression in human aortic endothelial cells. J Mol Cell Cardiol 2004;36:405-10.
27. Hung MJ, Cherng WJ, Yang NI, Cheng CW, Li LF. Relation of high-sensitivity C-reactive protein level with coronary vasospstic angina pectoris in patients without hemodynamically significant coronary artery disease. Am J Cardiol 2005;96:1484-90.
28. Jansson TH, Nilson TK, Johnson O. von Willebrand factor in plasma: a novel risk factor for recurrent myocardial infarction and death. Br Heart J 1991;66:351-5.
29. Meade TW, Cooper JA, Stirling Y, Howarth DJ, Ruddock V, Miller GJ. Factor VIII, ABO blood group and the incidence of ischemic heart disease. Br J Haematol 1994;88:601-7.
30. Synn YC, Bae JH, Kim KY. Correlation between endothelial function and the extent of coronary atherosclerosis. Korean Circ J 2004;34:752-60.