On limits of performance of DNA microarrays

ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings

Volumn 2, Issue , 2006, Pages

  Vikalo, H ^a   Hassibi, B ^a   Hassibi, A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA MICROARRAY; HYBRIDIZATION PROCESS; NON-SPECIFIC TARGETS; RAMIFICATIONS;

BINDING ENERGY; CONCENTRATION (PROCESS); CRAMER-RAO BOUNDS; MICROARRAYS; PROBABILITY; RANDOM PROCESSES; SHOT NOISE;

DNA;

EID: 33947630238     PISSN: 15206149     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (9)

1. M. Schena, Microarray Analysis, John Wiley & Sons, 2003.
2. U. R. Mller and D.V. Nicolau (Eds.), Microarray Technology and Its Applications, Springer, Berlin, Germany, 2005.
3. A. Hassibi, S. Zahedi, R. Navid, R. W. Dutton, and T. H. Lee, "Biological shot-noise and quantum-limited signal-to-noise ratio in affinity-based biosensors," J. Appl. Phys., 97, 084701, 2005.
4. Y. Tu, G. Stolovitzky, and U. Klein, "Quantitative noise analysis for gene expression microarray experiments," in Proceedings of National Academy of Science (PNAS), October 29, 2002, pp. 14031-14036.
5. A. Hassibi and H. Vikalo, "A probabilistic model for inherent noise and systematic errors of microarrays," Digest of IEEE International Workshop on Genomic Signal Processing and Statistics, 2005.
6. L. Kaderali and A. Schliep, "An algorithm to select target specific probes for DNA chips," Bioinformatics, 18(10), pp. 1340-1349, 2002.
7. J. SantaLucia, Jr. and D. Hicks, "The thermodynamics of DNA structural motifs", Annu. Rev. Biophys. Biomol. Struct. 33, 415-40, 2004.
8. H. Vikalo, B. Hassibi, and A. Hassibi, "A statistical model for microarrays, optimal estimation algorithms, and limits of performance," to appear in IEEE Trans. on Signal Processing.
9. H. Cramer, Mathematical Models of Statistics, Princeton University Press, Princeton, NJ 1946.