Characteristics and quality of randomized controlled trials in the treatment of hepatocellular carcinoma

Digestive Diseases and Sciences

Volumn 52, Issue 4, 2007, Pages 1108-1113

  Kaido, Toshimi ^a  

^a OTSU MUNICIPAL HOSPITAL   (Japan)

Author keywords

Evidence based medicine; Hepatocellular carcinoma; Intention to treat analysis; Randomized controlled trial; Sample size

Indexed keywords

ALCOHOL; ANTIANDROGEN; CISPLATIN; DOXORUBICIN; FLUOROURACIL; INTERFERON; TAMOXIFEN;

ARTICLE; ASIA; CANCER CHEMOTHERAPY; CANCER SURGERY; CANCER THERAPY; CHEMOEMBOLIZATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; EUROPE; FOLLOW UP; GEOGRAPHY; HORMONAL THERAPY; HUMAN; LIVER CELL CARCINOMA; MEDLINE; NORTH AMERICA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE;

CARCINOMA, HEPATOCELLULAR; HUMANS; LIVER NEOPLASMS; RANDOMIZED CONTROLLED TRIALS;

EID: 33947606487     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9618-y     Document Type: Article

References (17)

1. Ryder SD (2003) British Society of Gastroenterology. Guidelines for the diagnosis and treatment of hepatocellular carcinoma (HCC) in adults. Gut 52(Suppl 3):iii1-8
2. Van Vlierberghe H, Borbath I, Delwaide J, Henrion J, Michielsen P, Verslype C (2004) BASL HCC working group; BASL steering committee. BASL guidelines for the surveillance, diagnosis and treatment of hepatocellular carcinoma. Acta Gastroenterol Belg 67:14-25
3. Bruix J, Sherman M (2005) Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma. Hepatology 42:1208-1236
4. Evidence-Based Medicine Working Group (1992) Evidence-based medicine: A new approach to teaching the practice of medicine. JAMA 268:2420-2425
5. Moher D, Schulz KF, Altman D (2001) CONSORT Group. The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA 285:1987-1991
6. Shiina S, Teratani T, Obi S, Sato S, Tateishi R, Fujishima T, Ishikawa T, Koike Y, Yoshida H, Kawabe T, Omata M (2005) A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma. Gastroenterology 129:122-130
7. Barbare JC, Bouche O, Bonnetain F, Raoul JL, Rougier P, Abergel A, Boige V, Denis B, Blanchi A, Pariente A, Milan C, Bedenne L (2005) Randomized controlled trial of tamoxifen in advanced hepatocellular carcinoma. J Clin Oncol 23:4338-4346
8. Yeo W, Mok TS, Zee B, Leung TW, Lai PB, Lau WY, Koh J, Mo FK, Yu SC, Chan AT, Hui P, Ma B, Lam KC, Ho WM, Wong HT, Tang A, Johnson PJ (2005) A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/ doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma. J Natl Cancer Inst 97:1532-1538
9. Lin SM, Lin CJ, Lin CC, Hsu CW, Chen YC (2004) Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma < or = 4 cm. Gastroenterology 127:1714-1723
10. Groupe d'Etude et de Traitement duCarcinome Hepatocellulaire (2004) Randomized trial of leuprorelin and flutamide in male patients with hepatocellular carcinoma treated with tamoxifen. Hepatology 40:1361-1369
11. Chow PK, Tai BC, Tan CK, Machin D, Win KM, Johnson PJ, Soo KC Asian-Pacific Hepatocellular Carcinoma Trials Group (2002) High-dose tamoxifen in the treatment of inoperable hepatocellular carcinoma: a multicenter randomized controlled trial. Hepatology 36:1221-1226
12. Farinati F, De Maria N, Fornasiero A, Salvagnini M, Fagiuoli S, Chiaramonte M, Naccarato R (1992) Prospective controlled trial with antiestrogen drug tamoxifen in patients with unresectable hepatocellular carcinoma. Dig Dis Sci 37:659-662
13. Elba S, Giannuzzi V, Misciagna G, Manghisi OG (1994) Randomized controlled trial of tamoxifen versus placebo in inoperable hepatocellular carcinoma. Ital J Gastroenterol 26:66-68
14. Martinez Cerezo FJ, Tomas A, Donoso L, Enriquez J, Guarner C, Balanzo J, Martinez Nogueras A, Vilardell F (1994) Controlled trial of tamoxifen in patients with advanced hepatocellular carcinoma. J Hepatol 20:702-706
15. Castells A, Bruix J, Bru C, Ayuso C, Roca M, Boix L, Vilana R, Rodes J (1995) Treatment of hepatocellular carcinoma with tamoxifen: a double-blind placebo-controlled trial in 120 patients. Gastroenterology 109:917-922
16. CLIP Group (Cancer of the Liver Italian Programme) (1998) Tamoxifen in treatment of hepatocellular carcinoma: a randomised controlled trial. Lancet 352:17-20
17. Liu CL, Fan ST, Ng IO, Lo CM, Poon RT, Wong J (2000) Treatment of advanced hepatocellular carcinoma with tamoxifen and the correlation with expression of hormone receptors: a prospective randomized study. Am J Gastroenterol 95:218-222