Metformin and vitamin B12 deficiency: The role of H2 receptor antagonists and proton pump inhibitors [8]

Age and Ageing

Volumn 36, Issue 1, 2007, Pages 110-111

  Varughese, George I ^a   Scarpello, John H B ^b  

^a UNIVERSITY HOSPITAL OF NORTH STAFFORDSHIRE   (United Kingdom)

^b KEELE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CIMETIDINE; FAMOTIDINE; HISTAMINE H2 RECEPTOR ANTAGONIST; METFORMIN; NON PRESCRIPTION DRUG; PROTON PUMP INHIBITOR; ANTIDIABETIC AGENT; CYANOCOBALAMIN; PROTON PUMP;

CASE REPORT; CYANOCOBALAMIN DEFICIENCY; DIARRHEA; DRUG WITHDRAWAL; GASTRITIS; GASTROINTESTINAL SYMPTOM; HUMAN; INTESTINE ABSORPTION; LETTER; LONG TERM CARE; PRIORITY JOURNAL; TREATMENT DURATION; AGED; CHEMICALLY INDUCED DISORDER; DIABETES MELLITUS; DRUG ANTAGONISM; METABOLISM; NOTE;

AGED; AGED, 80 AND OVER; DIABETES MELLITUS; FAMOTIDINE; GASTRITIS; HISTAMINE H2 ANTAGONISTS; HUMANS; HYPOGLYCEMIC AGENTS; METFORMIN; PROTON PUMPS; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 33947585599     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afl139     Document Type: Letter

References (5)

1. Liu KW, Dai LK, Jean W. Metformin-related vitamin B12 deficiency. Age Ageing 2006; 35: 200-1.
2. Valuck RJ, Ruscin JM. A case-control study on adverse effects: H2 blocker or proton pump inhibitor use and risk of vitamin B12 deficiency in older adults. J Clin Epidemiol 2004; 57: 422-28.
3. Ruscin JM, Page RL II, Valuck RJ. Vitamin B (12) deficiency associated with histamine (2)-receptor antagonists and a proton-pump inhibitor. Ann Pharmacother 2002; 36: 812-16.
4. Salom IL, Silvis SE, Doscherholmen A. Effect of cimetidine on the absorption of vitamin B12. Scand J Gastroenterol 1982; 17: 129-31.
5. Scarpello JH, Hodgson E, Howlett HC. Effect of metformin on bile salt circulation and intestinal motility in type 2 diabetes mellitus. Diabet Med 1998; 15: 651-56.