MR spectroscopy and diffusion tensor imaging of the brain in congenital muscular dystrophy with merosin deficiency: Metabolite level decreases, fractional anisotropy decreases, and apparent diffusion coefficient increases in the white matter

Brain and Development

Volumn 29, Issue 5, 2007, Pages 317-321

  Sijens, P E ^a   Fock, J M ^a   Meiners, L C ^a   Potze, J H ^a   Irwan, R ^a   Oudkerk, M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Brain metabolism; Diffusion tensor imaging; Magnetic resonance imaging; Magnetic resonance spectroscopy; Merosin deficient congenital muscular dystrophy

Indexed keywords

ANTICONVULSIVE AGENT; CHOLINE; CREATINE; N ACETYLASPARTIC ACID; OXCARBAZEPINE; PHENYTOIN;

ADOLESCENT; ANISOTROPY; ARTICLE; BRAIN; CASE REPORT; DIFFUSION COEFFICIENT; DIFFUSION TENSOR IMAGING; DISEASE EXACERBATION; EDEMA; ELECTROMYOGRAPHY; GRAY MATTER; HUMAN; LABORATORY TEST; MALE; MEROSIN DEFICIENCY; MUSCLE BIOPSY; MUSCLE HYPOTONIA; MUSCULAR DYSTROPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITIVE END EXPIRATORY PRESSURE; PROTEIN DEFICIENCY; SEIZURE; WHITE MATTER;

ANISOTROPY; ASPARTIC ACID; BRAIN; BRAIN CHEMISTRY; CHILD; CHOLINE; DIFFUSION MAGNETIC RESONANCE IMAGING; HUMANS; LAMININ; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MUSCULAR DYSTROPHIES; MYELIN SHEATH;

EID: 33947584872     PISSN: 03877604     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.braindev.2006.10.004     Document Type: Article

References (11)

1. Pegoraro E., Marks H., Garcia C.A., Crawford T., Mancias P., Connolly A.M., et al. Laminin alpha2 muscular dystrophy: genotype/phenotype studies of 22 patients. Neurology 51 (1998) 101-110
2. Farina L., Morandi L., Milanesi I., Ciceri E., Mora M., Moroni I., et al. Congenital muscular dystrophy with merosin deficiency: MRI findings in five patients. Neuroradiology 40 (1998) 807-811
3. Gilhuis H.J., ten Donkelaar H.J., Tanke R.B., Vingerhoets D.M., Zwarts M.J., Verrips A., et al. Nonmuscular involvement in merosin-negative congenital muscular dystrophy. Pediatr Neurol 26 (2002) 30-36
4. Leite C.C., Reed U.C., Otaduy M.C.G., Lacerda M.T.C., Costa M.O.R., Ferreira L.G., et al. Congenital muscular dystrophy with merosin deficiency: 1H MR spectroscopy and diffusion-weighted MR imaging. Radiology 235 (2005) 190-196
5. Aslan M., Alkan A., Yakanci C., Sonmezgoz E., Bicak U., and Zorludemir S. Merosin-negative congenital muscular dystrophy: magnetic resonance spectroscopy findings. Brain Dev 27 (2005) 308-310
6. Sijens P.E., van den Bent M.J., Nowak P.J.C.M., van Dijk P., and Oudkerk M. 1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast. Magn Reson Med 37 (1997) 222-225
7. Sijens P.E., Mostert J.P., Oudkerk M., and De Keyser J. 1H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings. Eur Radiol 16 (2006) 489-495
8. Irwan R., Sijens P.E., Potze J.H., and Oudkerk M. Correlation of proton MR spectroscopy and diffusion tensor brain MR imaging. Magn Reson Imaging 23 (2005) 851-858
9. Sijens P.E., Boon M., Meiners L.C., Brouwer O.F., and Oudkerk M. 1H chemical shift imaging, MRI and diffusion-weighted imaging in vanishing white matter disease. Eur Radiol 15 (2005) 2377-2379
10. Ito J., Marmarou A., Barzo P., Fatouros P., and Corwin F. Characterization of edema by diffusion weighted imaging in experimental traumatic brain injury. J Neurosurg 84 (1996) 97-103
11. Lohle P.N., Wurzer H.A., Seelen P.J., Kingma L.M., and Go K.G. Analysis of fluid in cysts accompanying various primary and metastatic brain tumours: proteins, lactate and pH. Acta Neurochir (Wien) 140 (1998) 14-19