Assessing the efficacy of famotidine and rebamipide in the treatment of gastric mucosal lesions in patients receiving long-term NSAID therapy (FORCE - Famotidine or rebamipide in comparison by endoscopy)

Journal of Gastroenterology

Volumn 41, Issue 12, 2006, Pages 1178-1185

  Yamao, Jun Ichi ^a   Kikuchi, Eiryo ^b   Matsumoto, Masami ^c   Nakayama, Masaki ^d   Ann, Tatsuichi ^e   Kojima, Hideyuki ^a   Mitoro, Akira ^a   Yoshida, Motoyuki ^a   Yoshikawa, Masaaki ^a   Yajima, Hiroshi ^a   Miyauchi, Yoshizumi ^b   Ono, Hiroshi ^e   Akiyama, Koichi ^c   Sakurai, Goro ^d   Kinoshita, Yoshikazu ^f   Haruma, Ken ^g   Takakura, Yoshinori ^b   Fukui, Hiroshi ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY HOSPITAL   (Japan)

^c Nara Prefectural Gojo Hospital   (Japan)

^d Department of Urology   (Japan)

^e Kokuho Central Hospital   (Japan)

^f SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^g KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

Famotidine; Mucosal lesion; NSAID; Randomized study; Rebamipide

Indexed keywords

ACEMETACIN; DICLOFENAC; DISEASE MODIFYING ANTIRHEUMATIC DRUG; FAMOTIDINE; LOXOPROFEN; MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT; REBAMIPIDE; STEROID; ZALTOPROFEN; ALANINE; ANTIULCER AGENT; DRUG DERIVATIVE; QUINOLONE DERIVATIVE;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CLINICAL PROTOCOL; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG WITHDRAWAL; FEMALE; GASTROINTESTINAL ENDOSCOPY; HUMAN; LEUKOCYTE COUNT; LONG TERM CARE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SIDE EFFECT; STOMACH EROSION; STOMACH HEMORRHAGE; STOMACH MUCOSA LESION; THIRST; UREA NITROGEN BLOOD LEVEL; COMPARATIVE STUDY; MIDDLE AGED; PATHOLOGY; PEPTIC ULCER BLEEDING; STOMACH MUCOSA; STOMACH ULCER;

ADULT; AGED; ALANINE; ANTI-ULCER AGENTS; ENDOSCOPY, GASTROINTESTINAL; FAMOTIDINE; FEMALE; GASTRIC MUCOSA; HUMANS; MALE; MIDDLE AGED; PEPTIC ULCER HEMORRHAGE; QUINOLONES; STOMACH ULCER;

EID: 33947583318     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-006-1952-5     Document Type: Article

References (29)

1. Research Team for the Development of Guidelines for Evidence-Based Gastric Ulcer Diagnosis, Guideline for Clinical Practice of Gastric Ulcer Based on EBM (in Japanese with English abstract). Jiho 2003;7-14
2. JQ Huang S Sridhar RH Hunt 2002 Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: A meta-analysis Lancet 359 14-22 11809181 10.1016/S0140-6736(02)07273-2 1:CAS:528:DC%2BD38XmsV2msQ%3D%3D
3. M Asaka K Satoh K Sugano T Sugiyama S Takahashi T Shimoyama 2001 Guidelines in the management of Helicobacter pylori infection In Japan Helicobacter 6 177-86 11683920 10.1046/j.1523-5378.2001.00027.x 1:STN:280:DC%2BD3MnjsFalsA%3D%3D
4. H Miwa N Sakaki K Sugano H Sekine K Higucni T Sugiyama 2004 Recurrent peptic ulcers in patients following successful Helicobacter pylori eradication: A multicenter study of 4940 patients Helicobacter 9 9-26 15156899 10.1111/j.1083-4389.2004.00194.x
5. A Robert 1976 Antisecretory anti-ulcer, cytoprotective and diarrheogenic properties of prostaglandins Adv Prostaglandin Thromboxane Res 2 507-20 983858 1:CAS:528:DyaE28XhsVGjtbY%3D
6. M Ligumsky EM Golanska DG Hansen GL Kauffman 1983 Aspirin can inhibit gastric mucosal cyclo-oxygenase without causing lesions in rat Gastroenterology 84 756-61 6402412 1:CAS:528:DyaL2cXhtFCksbw%3D
7. M Frezza N Gorji M Melato 2001 The histopathology of non-steroidal anti-inflammatory drug induced gastroduodenal damage: Correlation with Helicobacter pylori, ulcers, and hemorrhagic events J Clin Pathol 54 521-5 11429423 10.1136/jcp.54.7.521 1:STN:280:DC%2BD3Mznt1Kqtw%3D%3D
8. T Funatsu K Chono T Hirata Y Keto A Kimoto M Sasamata 2004 The possible role of gastric acid against non-steroidal anti-inflammatory drugs-induced gastric microcirculatory disturbance in rats Jpn Pharmacol Ther 32 429-34 1:CAS:528:DC%2BD2cXntlOku7g%3D
9. AS Taha N Hudson CJ Hawkey AJ Swannell PE Trye J Cottrell 1996 Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs N Engl J Med 334 1435-9 8618582 10.1056/NEJM199605303342204 1:CAS:528:DyaK28XktF2kurk%3D
10. N Hudson AS Taha RI Russell P Trye J Cottrell SG Mann 1997 Famotidine for healing and maintenance in nonsteroidal anti-inflammatory drug-associated gastroduodenal ulceration Gastroenterology 112 1817-22 9178671 10.1053/gast.1997.v112.pm9178671 1:CAS:528:DyaK2sXjvFagtbg%3D
11. Y Keto T Funatsu T Hirata T Toyama K Sudoh M Sasamata 2003 Inhibitory effects of famotidine on NSAIDs and bisphosphonate-induced mucosal lesions in rats Jpn Pharmacol Ther 31 485-93 1:CAS:528:DC%2BD3sXmtFamtr4%3D
12. JB Raskin RH White JE Jackson AL Weaver EA Tindall RB Leis 1991 Misoprostol dosage in the prevention of nonsteroidal anti-inflammatory drug-induced gastric and duodenal ulcers: A comparison of three regimens Ann Intern Med 115 195-200
13. NM Agrawal HE Van Kerckhove LJ Erhardt GS Geis 1995 Misoprostol coadministered with diclofenac for prevention of gastroduodenal ulcers. A one-year study Dig Dis Sci 40 1125-31 7729275 10.1007/BF02064210 1:STN:280:ByqB2cnls10%3D
14. TS Bocanegra AL Weaver EA Tindall DH Sikes JA Ball CB Wallemark 1998 Diclofenac/misoprostol compared with diclofenac in the treatment of osteoarthritis of the knee or hip: A randomized, placebo controlled trial. Arthrotec Osteoarthritis Study Group J Rheumatol 25 1602-11 9712107 1:CAS:528:DyaK1cXlsF2gtrs%3D
15. RP Walt 1992 Misoprostol for the treatment of peptic ulcer and antiinflammatory-drug-induced gastroduodenal ulceration N Engl J Med 327 1575-80 1435885 1:STN:280:ByyD28zgs10%3D
16. K Katsuragi A Noda T Tachikawa A Azuma F Mukai K Murakami 1998 Highly sensitive urine-based enzyme-linked immunosorbent assay for detection of antibody to Helicobacter pylori Helicobacter 3 289-95 9844071 10.1046/ j.1523-5378.1998.08045.x 1:STN:280:DyaK1M%2Fmt1Smug%3D%3D
17. M Kato M Asaka M Saito H Sekine S Ohara T Toyota 2000 Clinical usefulness of urine-based enzyme-linked immunosorbent assay for detection of antibody to Helicobacter pylori: A collaborative study in nine medical institutions in Japan Helicobacter 5 109-19 10849061 10.1046/j.1523-5378.2000.00017.x 1:CAS:528:DC%2BD3cXksFSlsrc%3D
18. FL Lanza GL Royer RS Nelson TT Chen CE Seckman MF Rack 1981 A comparative endoscopic evaluation of the damaging effects of nonsteroidal anti-inflammatory agents on the gastric and duodenal mucosa Am J Gastroenterol 75 17-21 7234826 1:STN:280:Bi6B3cvjsVA%3D
19. Y Naito T Yoshikawa S Iinuma N Yagi K Matsuyama Y Boku 1998 Rebamipide protects against indomethacin-induced mucosal lesion in healthy volunteers in a double-blind, placebo-controlled study Dig Dis Sci 43 83-9
20. CJ Hawkey JA Karrasch L Szczepanski DG Walker A Barkun AJ Swannell 1998 Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group N Engl J Med 338 727-34 9494149 10.1056/NEJM199803123381105 1:CAS:528:DyaK1cXitFars7w%3D
21. CS Wu SH Wang PC Chen VCC Wu 1998 Dose famotidine have similar efficacy to misoprostol in the treatment of non-steroidal anti-inflammatory drug-induced gastropathy? Int J Clin Pract 52 472-4 10622088 1:CAS:528:DyaK1cXnslCjurc%3D
22. K Miyake N Ueki K Suzuki Y Shinji M Kusunoki T Hiratsuka 2005 Preventive therapy for non-steroidal anti-inflammatory drug-induced ulcers in Japanese patients with rheumatoid arthritis: The current situation and a prospective controlled-study of the preventive effects of lansoprazole or famotidine Aliment Pharmacol Ther 21 Suppl 2 67-72 15943850 10.1111/ j.1365-2036.2005.02477.x 1:CAS:528:DC%2BD2MXlvFShtbk%3D
23. K Kitagami K Oku N Umemoto Y Mizokami K Shiozama S Yamana 1993 Clinical study of rebamipide for NSAIDs induced gastritis J Adult Dis 23 1477-88
24. T Matsuhisa T Hayama H Nakamura S Yoshino N Yamada 1998 Clinical usefulness of rebamipide against symptoms, gastric lesions and histological gastritis caused by long-term administration of NSAIDs in patients with rheumatoid arthritis Gastroenterology (Tokyo) 27 118-30
25. Y Kinoshita C Kawanami K Kishi H Nakata Y Seino T Chiba 1997 Helicobacter pylori independent chronological change in gastric acid secretion in the Japanese Gut 41 452-8 9391241 1:STN:280:DyaK1c%2Flt1Kgsg%3D%3D
26. EM El-Omar ID Penman JES Ardill RS Chittajallu C Howie KEL Mccoll 1995 Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease Gastroenterology 109 681-91 7657096 10.1016/0016-5085(95)90374-7 1:CAS:528:DyaK2MXos1Grtbk%3D
27. M Feldman CT Richardson SK Lam IM Samloff 1988 Comparison of gastric acid secretion rates and serum pepsinogen I and II concentrations in occidental and oriental duodenal ulcer patients Gastroenterology 95 630-5 3396811 1:STN:280:BieB1cvhvVM%3D
28. H Kawaguchi K Haruma K Komoto M Yoshihara K Sumii G Kajiyama 1996 Helicobacter pylori infection is the major risk factor for atrophic gastritis Am J Gastroenterol 91 959-62 8633588 1:STN:280:BymB3M3nt10%3D
29. K Haruma T Kamada H Kawaguchi S Okamoto M Yoshihara K Sumii 2000 Effect of age and Helicobacter pylori infection on gastric acid secretion J Gastroenterol Hepatol 15 277-83 10764028 10.1046/ j.1440-1746.2000.02131.x 1:STN:280:DC%2BD3c3isFSqug%3D%3D