Germa-γ-lactones as novel inhibitors of bacterial urease activity

Biochemical and Biophysical Research Communications

Volumn 356, Issue 2, 2007, Pages 457-463

  Amtul, Zareen ^a   Follmer, Cristian ^b   Mahboob, Sumera ^c   Atta Ur Rahman, ^a   Mazhar, Muhammad ^c   Khan, Khalid M ^a   Siddiqui, Rafat A ^a,d   Muhammad, Sajjad ^e   Kazmi, Syed A ^a   Choudhary, Mohammad Iqbal ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c QUAID I AZAM UNIVERSITY   (Pakistan)

^d METHODIST RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Enzyme inhibition; Enzyme kinetics; Germa lactones; Noncompetitive inhibitor; Proteus mirabilis; Urease

Indexed keywords

2 METHYL 8 QUINOLINE; BACTERIAL ENZYME; BETA (2 METHOXYPHENYL) GAMMA,GAMMA BIS(8 QUINOLINOXY)GERMA GAMMA LACTONE; BETA (2 METHYLPHENYL) GAMMA,GAMMA BIS(8 QUINOLINOXY)GERMA GAMMA LACTONE; GAMMA LACTONE DERIVATIVE; GERMANIUM DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; UREASE; UREASE INHIBITOR;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL GROWTH; CLOSTRIDIUM PASTEURIANUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; IC 50; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEUS MIRABILIS; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; URINARY TRACT INFECTION;

ANTI-BACTERIAL AGENTS; BACTERIA; ENZYME INHIBITORS; LACTONES; MICROBIAL SENSITIVITY TESTS; PROTEUS MIRABILIS; UREASE;

BACILLI (CLASS); BACTERIA (MICROORGANISMS); NEGIBACTERIA; PROTEUS MIRABILIS;

EID: 33947516863     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.02.158     Document Type: Article

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