Hemoglobin-oxygen-affinity and acid-base properties of blood from the fossorial mole-rat, Cryptomys hottentotus pretoriae

Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology

Volumn 147, Issue 1, 2007, Pages 50-56

  van Aardt, W J ^a   Bronner, G ^b   Buffenstein, Rochelle ^c  

^a NORTH WEST UNIVERSITY   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c CITY COLLEGE OF NEW YORK   (United States)

Author keywords

Acid base balance; Hemoglobin; Hypercapnia; Mole rat; P50; Whole blood

Indexed keywords

2,3 DIPHOSPHOGLYCERIC ACID; BICARBONATE; CARBON DIOXIDE; HEMOGLOBIN; OXYGEN;

ACID BASE BALANCE; ARTICLE; BICARBONATE BLOOD LEVEL; BLOOD PH; BODY TEMPERATURE; CARBON DIOXIDE BLOOD LEVEL; CONTROLLED STUDY; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN BLOOD LEVEL; HEMOLYSATE; MOLE RAT; NONHUMAN; OXYGEN AFFINITY; OXYGEN BLOOD LEVEL; OXYGEN DISSOCIATION CURVE; OXYGEN SUPPLY; TONOMETRY;

ANIMALIA; CRYPTOMYS HOTTENTOTUS; CRYPTOMYS HOTTENTOTUS PRETORIAE; MAMMALIA; RATTUS;

EID: 33947512739     PISSN: 10956433     EISSN: 15314332     Source Type: Journal    
DOI: 10.1016/j.cbpa.2006.11.016     Document Type: Article

References (41)

1. Ar A. Physiological adaptations to underground life in mammals. In: Dejours P. (Ed). 8th ESCP Conference, Strasbourg 1986, Krager, Basel. Comparative Physiology of Environmental Adaptations vol. 2 (1987) 208-211
2. Ar A., Arieli R., and Shkolnik A. Blood-gas properties and functioning of the fossorial mole rat under normal and hypoxic-hypercapnic atmospheric conditions. Respir. Physiol. 30 (1977) 201-218
3. Arieli R. The atmospheric environment of the fossorial mole-rat (Spalax ehrenbergi) effects of season, soil texture, rain, temperature and activity. Comp. Biochem. Physiol. A 63 (1979) 569-575
4. Arieli R. Adaptation of the mammalian gas transport system to subterranean life. Prog. Clin. Biol. Res. 335 (1990) 251-268
5. Arieli R., Heth G., Nevo E., Zamir Y., and Neutra O. Hematocrit and hemoglobin in four chromosomal species and some isolated populations of actively speciating subterranean mole rats in Israel. Experientia 42 (1986) 441-443
6. Bennett N.C., Jarvis J.U.M., and Davies K.C. Daily and seasonal temperatures in the burrows of African rodent moles. S. Afr. J. Zool. 23 (1988) 189-195
7. Bennett N.C., Clark B.C., and Jarvis J.U.M. A comparison of metabolic acclimation in two species of social mole-rats (Rodentia, Bathyergidae) in southern Africa. J. Arid Environ. 22 (1992) 189-198
8. Boggs D.F. Hypoxic ventilatory control and hemoglobin oxygen affinity. In: Sutton J.R., Houston C.S., and Coates Jr. G. (Eds). Hypoxia and The Brain (1995), Queen City Press, Burlington, Vermont 69-88
9. Boggs D.F., Kilgore Jr. D.L., and Birchard G.F. Respiratory physiology of burrowing mammals and birds. Comp. Biochem. Physiol. A 77 (1984) 1-7
10. Boggs D.F., Maginniss L.A., and Kilgore Jr. D.L. In vivo blood oxygen binding in hypoxic lesser spear-nosed bats: relationship to control breathing. Respir. Physiol. 118 (1999) 193-202
11. Broekman M.S., Bennett N.C., Jackson C.R., and Weber R.E. Does altitudinal difference modulate the respiratory properties in subterranean rodent (Cryptomys hottentotus mahali) blood?. Physiol. Behav. 88 (2006) 77-81
12. Buffenstein R. Ecophysiological responses to a subterranean habitat: a bathyergid perspective. Mammalia 60 (1996) 591-605
13. Buffenstein R. Ecophysiological responses to an underground habitat. In: Lacey E., Patton J., and Cameron G. (Eds). The Biology of Subterranean Rodents (2000), Chicago University Press, Chicago 62-110
14. Cameron J.N. Rapid method for determination of total carbon dioxide in small blood samples. J. Appl. Physiol. 31 (1971) 632-634
15. Chapman R.C., and Bennett A.F. Physiological correlates of burrowing in rodents. Comp. Biochem. Physiol. A 51 (1975) 599-603
16. Darden T.R. Respiratory adaptations of the fossorial mammal, the pocket gopher (Thomomys bottae). J. Comp. Physiol. 78 (1972) 121-137
17. Davenport H.W. The ABC of Acid-Base Chemistry (1974), The University of Chicago Press, Chicago
18. Dejours P. Principles of Comparative Respiratory Physiology (1975), North-Holland/ American Elsevier, Amsterdam
19. De Villiers B., and Mangold S. The Biophysical Environment. In: Mangold S. (Ed). State of the Environment Report 2002. North-West Province Department of Agriculture, Conservation and the Environment, Mmabatho, South Africa (2002) 14-23
20. Dolman D., and Gill S.J. Membrane covered thin-layer optical cell for gas-reaction studies of hemoglobin. Anal. Biochem. 87 (1978) 127-134
21. Gill S. Measurements of oxygen binding by means of a thin-layer optical cell. Methods Enzymol. 76 (1981) 427-438
22. Haim A., Heth G., Nevo E., Gruener N., and Goldstein T. Urine analyses of three rodent species with emphasis on calcium and magnesium bicarbonate. Comp. Biochem. Physiol. A 80 (1985) 503-506
23. Hickman G. A live-trap and trapping technique for fossorial mammals. S. Afr. J. Zool. 14 (1979) 9-12
24. Jelkmann W., Oberthur W., Kleinschmidt T., and Braunitzer G. Adaptation of hemoglobin function to subterranean life in the mole Talpa europea. Respir. Physiol. 46 (1981) 7-16
25. Johansen K., Lykkeboe G., Weber R.E., and Maloiy G.M.O. Blood respiratory properties in the naked mole rat Heterocephalus glaber, a mammal of low body temperature. Respir. Physiol. 28 (1976) 303-314
26. Kleinschmidt T., Nevo E., Goodman M., and Braunitzer G. Mole rat hemoglobin: primary structure and evolutionary aspects in a second karyotype of Spalax ehrenbergi, Rodentia (2n = 52). Biol. Chem. Hoppe-Seyler 366 (1985) 679-685
27. Lahiri S. Blood oxygen affinity and alveolar ventilation in relation to body weight in mammals. Am. J. Physiol. 229 (1975) 529-536
28. Lechner A.J. Respiratory adaptations in burrowing pocket gophers from sea level and high altitude. J. Appl. Physiol. 41 (1976) 168-173
29. Morris S. Organic ions as modulators of respiratory pigment function during stress. Physiol. Zool. 63 (1990) 253-287
30. Nikinmaa M. Hemoglobin function in vertebrates: evolutionary changes in cellular regulation in hypoxia. Respir. Physiol. 128 (2001) 317-329
31. Riggs A. The nature and significance of the Bohr effect in mammalian hemoglobins. J. Gen. Physiol. 43 (1960) 737-752
32. Riggs A. Preparation of blood hemoglobins of vertebrates. Methods Enzymol. 76 (1981) 5-29
33. Roper T.J., Bennett N.C., Conradt T., and Molteno A.J. Environmental conditions in burrows of two species of African mole-rat, Georychus capensis and Cryptomys damarensis. J. Zool., Lond. 254 (2001) 101-107
34. Saldívar E., Cabrales P., Tsai A.G., and Intaglietta M. Microcirculatory changes during chronic adaptation to hypoxia. Am. J. Physiol. 285 (2003) H2064-H2071
35. Samanja M. Blood gas transport at high altitude. Respiration 64 (1997) 422-428
36. 2-binding curves of hemoproteins by means of a diffusion chamber. Anal. Biochem. 32 (1969) 362-376
37. Tucker V.A. Method for oxygen content and dissociation curves on microlitre blood samples. J. Appl. Physiol. 23 (1967) 410-414
38. van Aardt W.J. Die meting van die suurstofbindingseienskappe van hemosianien met behulp van 'n dunlaag optiese sel. S. A. Tydskr. Natuurwet. Tegnol. 11 (1992) 62-68
39. Van Aardt W.J., Bronner G.N., and de Necker M.-L. Oxygen dissociation curves of whole blood from the Egyptian free-tailed bat, Tadarida aegyptica E. Geoffroy, using a thin-layer optical cell. Afr. Zool. 37 (2002) 109-113
40. Weber R.E., Heath M.E., and White F.N. Oxygen binding functions of blood and hemoglobin from the Chinese pangolin, Manis pentadactyla: possible implications of burrowing and low body temperature. Respir. Physiol. 64 (1986) 103-112
41. Widmer H.P., Hoppeler H., Nevo E., Taylor C.R., and Weibel E.W. Working underground: respiratory adaptations in the blind mole rat. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 2062-2067