Drug release properties of polymer coated ion-exchange resin complexes: Experimental and theoretical evaluation

Journal of Pharmaceutical Sciences

Volumn 96, Issue 3, 2007, Pages 618-632

  Seong, Hoon Jeong ^a   Berhane, Nahor Haddish ^a   Haghighi, Kamyar ^a   Park, Kinam ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Diffusion; Drug delivery; Fluid bed coating; Ion exchange resin; Mathematical modeling

Indexed keywords

DEXTROMETHORPHAN; DOWEX; ION EXCHANGE RESIN; KOLLICOAT; POLYMER; POLYVINYL ACETATE; UNCLASSIFIED DRUG;

ARTICLE; CONFOCAL LASER MICROSCOPY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; SCANNING ELECTRON MICROSCOPE;

EID: 33947501530     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20677     Document Type: Article

References (29)

1. Lowenthal W. 1972. Mechanism of action of tablet disintegrants: Correlation of tablet mean pore diameter and porosity. J Pharm Sci 61:303-304.
2. Elder DP. 2005. Pharmaceutical applications of ion-exchange resins. J Chem Educ 82:575-587.
3. Agarwal R, Mittal R, Singh A. 2000. Studies of ion-exchange resin complex of chloroquine phosphate. Drug Dev Ind Pharm 26:773-776.
4. Atyabi F, Sharma HL, Mohammad HAH, Fell JT. 1996. Controlled drug release from coated floating ion exchange resin beads. J Control Release 42:25-28.
5. Bhaskar R, Murthy RSR, Miglani BD, Viswanathan K. 1986. Novel Method to evaluate diffusion controlled release of drug from resinate. Int J Pharm 28:59-66.
6. Ichikawa H, Fujioka K, Adeyeye MC, Fukumori Y. 2001. Use of ion-exchange resins to prepare 100 mm-sized microcapsules with prolonged drug-release by the Wurster process. Int J Pharm 216:67-76.
7. Langer DL. 1993. Polymer-controlled drug delivery systems. Acc Chem Res 26:537-542.
8. Motycka S, Nairn JG. 1979. Preparation and evaluation of microencapsulated ion-exchange resin beads. J Pharm Sci 68:211-215.
9. Borgquist P, Zackrisson G, Nilsson B, Axelsson A. 2002. Simulation and parametric study of a film-coated controlled-release pharmaceutical. J Control Release 80:229-245.
10. Farrell S, Sirkar KK. 2001. A mathematical model of a hybrid disperssed network-membrane based controlled release system. J Control Release 70:51-61.
11. Farrell S, Sirkar KK. 1999. A mathematical model of an acqueous-organic partition based controlled release system using microporous membranes. J Control Release 61:345-360.
12. Frenning G, Tunon A, Alderborn G. 2003. Modelling of drug release from coated granular pellets. J Control Release 92:113-123.
13. Koizumi T, Ritthidej GC, Phaechamud T. 2001.Mechanistic modeling of drug release from chitosan coated tablets. J Control Release 70:277-284.
14. Lee DJ, Liao YC. 1995. Slow-release from a coated sphere with slightly deformed coating. J Pharm Sci 84:1366-1373.
15. Liao YC, Lee DJ. 1997. Slow-release from a coated sphere with slight deformations of coating film and drug matrix. J Pharm Sci 86:92-100.
16. Sirotti C, Colombo M, Grassi M. 2002. Modeling of drug release from poly-disperse microencupsulated spherical particles. J Microencupsulation 19:603-614.
17. Du C, Zhou J, Shaviv A, Wang H. 2004. Mathematical model for potassium release from polymer-coated fertiliser. Biosyst Eng 88:395-400.
18. Lu SM, Lee SF. 1992. Slow release of Urea through latex film. J Control Release 18:171-180.
19. Higuchi T. 1961. Rate of release of medicaments from ointment bases containing drugs in suspension. J Pharm Sci 50:874-875.
20. Korsemeyer RW, Gurny R, Doelker EM, Buri P, Peppas NA. 1983. Mechanism of solute release-from porous hydrophilic polymers. Int J Pharm 15:25-30.
21. Peppas NA. 1985. Analysis of Fickian and non-Fickian drug release from polymers. Pharm Acta Helv 60:110-111.
22. Boyd GE, Adamson AW, Myers LS, Jr. 1947. The exchange adsorption of ions from aqueous solutions by organic zeolites. II. Kinetics. J Am Chem Soc 69:2836-2848.
23. Reichenberg D. 1953. Properties of ion-exchange resins in relation to their structure. III. Kinetics of exchange. J Am Chem Soc 75:589-597.
24. Costa P, Sousa Lobo JM. 2001. Modeling and comparison of dissolution profiles. Eur J Pharm Sci 13:123-133.
25. Motycka S, Nairn JG. 1978. Influence of wax coatings on release rate of anions from ion-exchange resin beads. J Pharm Sci 67:500-503.
26. Helfferich F. 1962. Ion Exchnage. editor, New York: McGraww-Hill. p 624.
27. Siepmann J, Peppas NA. 2001. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv Drug Deliv Rev 48:139-157.
28. Pongjanyakul T, Prakongpan S, Rungsardthong U, Chancham P, Priprem A. 2005. Characteristics and in vitro release of dextromethorphan resinates. Powder Technol 152:100-106.
29. Hering B, Bliss H. 1963. Diffusion in ion exchange resins. AIChE J 9:495-503.