A liquid chromatography-mass spectrometry method for the quantification of urinary albumin using a novel 15N-isotopically labeled albumin internal standard [6]

Clinical Chemistry

Volumn 53, Issue 3, 2007, Pages 540-542

  Singh, Ravinder ^a,c   Crow, Frank W ^a   Babic, Nikolina ^a   Lutz, Ward H ^a   Lieske, John C ^a   Larson, Timothy S ^a   Kumar, Rajiv ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN;

CARDIOVASCULAR RISK; HUMAN; ISOTOPE LABELING; LETTER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROALBUMINURIA; PROTEIN URINE LEVEL;

ALBUMINURIA; CHROMATOGRAPHY, LIQUID; HUMANS; ISOTOPE LABELING; MASS SPECTROMETRY; NITROGEN ISOTOPES; REFERENCE STANDARDS; SERUM ALBUMIN;

EID: 33947427090     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2006.078832     Document Type: Letter

References (5)

1. Venkat KK. Proteinuria and microalbuminuria in adults: significance, evaluation, and treatment. South Med J 2004;97:969-79.
2. Karalliedde J, Viberti G. Microalbuminuria and cardiovascular risk. Am J Hypertens 2004;17:986-93.
3. Sviridov D, Meilinger B, Drake SK, Hoehn GT, Hortin GL. Coelution of other proteins with albumin during size-exclusion HPLC: implications for analysis of urinary albumin. Clin Chem 2006;52:389-97.
4. Babic N, Larson TS, Grebe SK, Turner ST, Kumar R, Singh RJ. Application of liquid chromatography-mass spectrometry technology for early detection of microalbuminuria in patients with kidney disease. Clin Chem 2006;52:2155-7.
5. Loo JA, Edmonds CG, Smith RD. Tandem mass spectrometry of very large molecules: serum albumin sequence information from multiply charged ions formed by electrospray ionization. Anal Chem 1991;63:2488-99.