Modelling of amperometric biosensors in the case of substrate inhibition

Sensors

Volumn 6, Issue 11, 2006, Pages 1513-1522

  Kulys, Juozas ^a   Baronas, Romas ^b  

^a VILNIUS GEDIMINAS TECHNICAL UNIVERSITY   (Lithuania)

^b VILNIUS UNIVERSITY   (Lithuania)

Author keywords

Biosensor; Diffusion; Enzyme inhibition; Modelling

Indexed keywords

BIOSENSORS; CARRIER MOBILITY; DIFFUSION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYMES; KINETICS; MODELS;

AMPEROMETRIC BIOSENSORS; DIFFUSION LIMITATIONS; FINITE-DIFFERENCE TECHNIQUES; MICHAELIS-MENTEN CONSTANT; STEADY-STATE CONDITION; SUBSTRATE CONCENTRATIONS; SUBSTRATE DIFFUSION; SUBSTRATE INHIBITION;

ENZYME INHIBITION;

EID: 33947423387     PISSN: 14243210     EISSN: 14248220     Source Type: Journal    
DOI: 10.3390/s6111513     Document Type: Article

References (18)

1. Kulys, J. The development of new analytical systems based on biocatalysts. Anal. Lett. 1981, 14, 377-397.
2. Baronas, R.; Ivanauskas, F.; Kulys J. Modelling of a microreactor on heterogeneous surface and the influence of geometry to microreactor operation. Nonlinear Anal. Model. Control 1998, 3, 19-30.
3. Baronas, R.; Ivanauskas, F.; Kulys J. Modelling a biosensor based on the heterogeneous microreactor. J. Math. Chem. 1999, 25, 245-252.
4. Baronas, R.; Ivanauskas, F.; Kulys, J.; Sapagovas, M.; Survila A. The influence of diffusion space geometry on behavior of some processes in biochemistry and electrochemistry. Nonlinear Anal. Model. Control 2000, 5, 3-38.
5. Baronas, R.; Ivanauskas, F.; Kulys, J. Modelling dynamics of amperometric biosensors in batch and flow injection analysis. J. Math. Chem. 2002, 32, 225-237.
6. Baronas, R.; Christensen, J.; Ivanauskas, F.; Kulys, J. Computer simulation of amperometric biosensor response to mixtures of compounds. Nonlinear Anal. Model. Control 2002, 7, 3-14.
7. Baronas, R.; Ivanauskas, F.; Kulys, J. Computer simulation of the response of amperometric biosensors in stirred and non-stirred solution. Nonlinear Anal. Model. Control 2003, 8, 3-18.
8. Baronas, R.; Ivanauskas, F.; Kulys, J. The Influence of enzyme membrane thickness on the response of amperometric biosensors. Sensors 2003, 3, 248-262.
9. Baronas, R.; Ivanauskas, F.; Kulys, J.; Sapagovas, M. Modelling of amperometric biosensors with rough surface of the enzyme membrane. J. Math. Chem. 2003, 34, 227-242.
10. Ivanauskas, F.; Baronas, R.; Kulys, J.; Sapagovas, M. Modelling of surface roughness of enzyme layer of amperometric biosensors. Lithuan. Math. J. 2003, 43, 625-629.
11. Baronas, R.; Ivanauskas, F.; Kulys, J.; Sapagovas, M. Computational modelling of a sensor based on an array of enzyme microreactors. Nonlinear Anal. Model. Control 2004, 9, 203-218.
12. Baronas, R.; Kulys, J.; Ivanauskas, F. Modelling amperometric enzyme electrode with substrate cyclic conversion. Biosen. Bioelectron. 2004, 19, 915-922.
13. Baronas, R.; Ivanauskas, F.; Kulys, J. The effect of diffusion limitations on the response of amperometric biosensors with substrate cyclic conversion. J. Math. Chem. 2004, 35, 199-213.
14. Baronas, R.; Kulys, J.; Ivanauskas, F. Mathematical model of the biosensors acting in a trigger mode. Sensors 2004, 4, 20-36.
15. Baronas, R.; Kulys, J.; Ivanauskas, F. Computational modelling of biosensors with perforated and selective membranes. J. Math. Chem. 2006, 39, 345-362.
16. Baronas, R.; Ivanauskas, F.; Kulys, J. Mathematical modelling of biosensors based on an array of enzyme microreactors. Sensors 2006, 6, 453-465.
17. Gufreund, H. Kinetics for the life sciences. Cambridge: Cambridge University Press, 1995, p. 346.
18. Kulys, J. Biosensor response at mixed enzyme kinetics and external diffusion limitation in case of substrate inhibition. Nonlinear Anal. Model. Control 2006, 11, 1-8.