The antiplasmodial agents of the stem bark of Entandrophragma angolense (Meliaceae)

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 4, Issue 2, 2007, Pages 135-139

  Bickii, Jean ^a   Tchouya, Guy Raymond Feuya ^b   Tchouankeu, Jean Claude ^b   Tsamo, Etienne ^b  

^a Laboratoire de Recherche sur le Paludisme Yaounde   (Cameroon)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

24 methylenecycloartenol; 7 obacunyl acetate; Anti plasmodial activity; Entandrophragma angolense; Fatty acids; Limonoids; Meliaceae; Plasmodium falciparum; Triterpenoids

Indexed keywords

22 HYDROXYHOPAN 3 ONE; 24 METHYLENE CYCLOARTENOL; 7ALPHA ACETOXYDIHYDRONOMILIN; 7ALPHA OBACUNYLACETATE; ANTIMALARIAL AGENT; CHLOROQUINE; DICHLOROMETHANE; ENTANDROPHRAGMA ANGOLENSE EXTRACT; LIMONOID; METHANOL; METHYLANGOLENSATE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; TRICOSANOIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BARK; CONTROLLED STUDY; DRUG ACTIVITY; ENTANDROPHRAGMA ANGOLENSE; IC 50; ISOLATION PROCEDURE; MELIACEAE; NONHUMAN; PLASMODIUM FALCIPARUM;

EID: 33947409840     PISSN: 01896016     EISSN: 01896016     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Ahmed, F. R. and No, A. S., Fallis A. G. (1978). 7α-acetoxydihydronomilin: isolation, spectra, and crystal structure, Can. J. Chem., 56: 1020-1025.
2. Aubreville, A. (1950). Flore forestière Soudano-guinéeme. Société d'édition géographique, p. 377.
3. Bennett R. D. and Hasegawa S. (1982). 7α-Oxygenated limonoids from the Rutaceae. Phytochemistry, 21(9): 2349-2354.
4. Bickii, J., Njifutie, N., Ayafor, J. F., Basco, L. K., Ringwald, P. (2000). In vitro antimalarial activity of limonoids from Khaya grandifoliola C. D. C. (Meliaceae). J. Ethnopharmacol., 69: 27-33.
5. Bray, D. H., Warhurst, D. C., Connolly, J. D., O'Neill, M. J., Phillipson, J. D. (1990). Plants as sources of antimalarial drugs. Part 7. Activity of some species of Meliaceae and their constituent limonoids. Phytother. Res., 4: 29-35.
6. Connolly, J. D. (1983). The Chemistry and Taxonomy of the Rutales. In: P. G. Waterman and M. F. Grundon (Eds.), Academic Press London, p. 180.
7. Ferreira, J., Floriani, A. E. O., Filho, V. C., Monache, F. D., Yunes, R. A., Calixto, J. B. and Santos, A. R. S. (2000). Antinociceptive properties of the methanolic extract and two triterpenes isolated from Epidendrum mosenii stems (Orchidaceae), Life Sciences, 66(9): 791-802.
8. Francis, F. (1939). The Higher n-Aliphatic Acids and their Methyl and Ethyl Esters. J. Am. Chem. Soc., 61: 577-581.
9. Furuya, T., Oriharia, Y. and Hayashi, C. (1987). Triterpenoids from Eucalyptus perriniana cultured cells*. Phytochemistry, 26: 715-719.
10. Glen, A. T., Lawrie, W., Mclean, J. and Garby Younes, M. (1967). Terpenoid Constituents of Rose-bay Willow-herb. J. Chem. Soc. (C) 510-515.
11. Irvine, F. R. (1961). Woody plants of Ghana. Oxford Univerity Press. Oxford, p 517.
12. Koumaglo, K., Gbeassor, M., Nikabu, O., De Souza, C., Werner, W. (1991). Effects of three compounds extracted from Morinda lucida on Plasmodium falciparum. Planta med., 58: 533-534.
13. Lambros C., Vanderberg J. P. (1979). Synchronization of Plasmodium falciparum erythrocytic stages in culture. J. Parasitol., 65: 418-420
14. e. Institut de la Carte Internationale de la Végétation, Toulouse, France, p. 5.
15. 13C NMR Spectra of pentacyclic Triterpenoids-A Compilation and some salient features. Phytochemistry, 37:1517-1575.
16. Nkunya, M. H. H., Weenen, H., Bray, D. H., Mgani Q. A. (1991). Anti-malarial activity of Tanzanian plants and their active constituents: the genus Uvaria. Planta med., 57: 341-343.
17. Noster, S., Kraus, L. J. (1990). In vitro activity of Coutera latiflora and Exosreme caribaeum extracts on Plasmodium falciparum. Planta med., 56: 63-65.
18. Obih, P. O., Makinde, J. M., Laoje, J. (1986). Investigation of various extracts of Morinda lucida for antimalarial actions on Plasmodium berghei in mice. Afr. J. Med. Sci., 14: 45-49.
19. O'Neill, M. J., Bray, D. H., Boardman, P., Phillipson, J. D., Warhurst, D. C., Peters, W., Suffness, M. (1986). Plants as source of anti-malarial drugs: in vitro antimalarial activities of some quassinoids. Antimicrob. Agents Chemother., 30: 101-104.
20. Phillipson, J. D., Wright, C. W. (1991). Antiprotozoal agents from plants sources. Planta med., 57 (Suppl 1): S53-S59.
21. Sakakibara, J., Kaiya, T., Furuda, H. and Ohki, T. (1983). 6- beta (mathemathiq)-hydroxyursolic acid and other tritepenoids of Enkianthus cernuus. Phytochemistry, 22: 2553-2559.
22. Singh A., Rosenthal P. J. (2001). Comparison of efficacies of cysteine protease inhibitors against five strains of Plasmodium falciparum. Antimicrob. Agents Chemother., 45: 949-951.
23. Weenen, H., Nkunya, M. H. H., Bray, D. H., Mwasumbi, L. B., Kinabo, L. S., Kilimali, V. A. E. B. (1990a). Antimalarial activity of Tanzanian medicinal plants. Planta Med., 56: 368-370.
24. Weenen, H., Nkunya, M. H. H., Bray, D. H., Mwasumbi, L. B., Kinabo, L. S., V. A. E. B. (1990b). Antimalarial compounds containing an α, β-unsaturared carbonyl moiety from Tanzanian medicinal plants. Planta med., 56: 371-373.