Gadolinium-diethylenetriaminepenta-acetic acid conjugated with monoclonal antibody C595 as new magnetic resonance imaging contrast agents for breast cancer (MCF-7) detection

Iranian Biomedical Journal

Volumn 10, Issue 4, 2006, Pages 209-213

  Shahbazi Gahrouei, Daryoush ^a   Roufeh, Mariam ^a   Tavakoli, Mohammad Bagher ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Breast cancer; Gadolinium; Magnetic resonance imaging (MRI); Monoclonal antibody

Indexed keywords

ACID ANHYDRIDE; CONTRAST MEDIUM; GADOLINIUM PENTETATE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY C595; TRASTUZUMAB; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CELL MEMBRANE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; NUCLEAR MAGNETIC RESONANCE IMAGING; RELAXATION TIME; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 33947401420     PISSN: 1028852X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Unger, E.C., Totty, W.G., Otsuka, F.L., Murphy, W.A., Welch, M.S., Connett, J.M. and Philpott, G.W. (1985) Magnetic resonance imaging using gadolinium-labeled monoclonal antibody. Invest. Radiol. 20: 693-700.
2. Andersen-Berg, W.T., Strand, M., Lempert, T.E., Rosenbaum, A.E. and Joseph, P.M. (1986) Nuclear magnetic resonance and gamma camera tumor imaging using gadolinium-labeled monoclonal antibodies. J. Nucl. Medicine 27: 829-833.
3. Curtet, C., Bourgoin, C. and Bohy, J. (1988) Gd-25DTPA-Mab, a potential NMR contrasts agent for MRI in the xenografted nude mouse: preliminary studies. Int. J. Cancer [Suppl 2]: 126-132.
4. Goher-Rosental, S., Schmitt-Willich, H., Ebert, W. and Conard, J. (1993) The determination of human tumors on nude mice using gadolinium-labeled monoclonal antibodies for magnetic resonance imaging. Invest. Radiol. 28 (9): 389-395.
5. Pressman, D. and Korngold, L. (1953) The in vivo localization of anti-Wagner osteogenic sarcoma antibodies. Cancer 6: 619-623.
6. Kohler, G. and Milstein, C. (1975) Continuous cultures of fused cells secreting antibodies of predefined specificity. Nature 256: 495-497.
7. Mach, J.P., Buchegger, R. and Forni, M. (1981) Use of radiolabeled monoclonal anti-CEA antibodies for the detection of human carcinomas by external photo scanning and tomoscintigraphy. Immunol. Today 2: 239-249.
8. Lauffer, R.B. (1987) Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: theory and design. Chem. Rev. 87: 901-927.
9. Cerdan, S., Lotscher, H.R., Kunnecke, B. and Seelig, J. (1989) Monoclonal antibody-coated magnetic particles as contrast agents in magnetic resonance imaging of tumors. Magn. Reson. Med. 12: 151-163.
10. Shahbazi-Gahrouei, D., Williams, M., Rizvi, S.M. and Allen, B.J. (2001) In vivo studies of Gd-DTPA-monoclonal antibody and Gd-porphyrins: potential MR imaging contrast agents for melanoma. J. Magn. Reson. Imaging 14 (2): 169-174.
11. Matsumura, A., Shibata, Y., Nakagawa, K. and Nose, T. (1994) MRI contrast enhancement by Gd-DTPA-monoclonal antibody in 9L glioma rats. Acta Neurochir. [Suppl] 60: 356-358.
12. 1 MRI with Gadomer-17. J. Magn. Reson. Imaging 47 (2): 305-313.
13. Silvio, A., Alessandro, B., Daniela, D.H., Franco, F., Arnando, M., Fleming, U.N. and Enzo, T. (2002) Paramagnetic lanthanide (III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI application. J. Magn. Reson. Imaging 47 (2): 639-648.
14. Shapiro, M.G., Atanasijevic, T., Faas, H., Westmeyer, G.G. and Gasanoff, A. (2006) Dynamic imaging with MRI contrast agents: quantitative considerations. Magn. Reson. Imaging 24: 449-462.
15. Shahbazi-Gahrouei, D., Williams, M., Rizvi, S. and Allen, B.J. (2002) In vitro studies of gadolinium-DTPA conjugated with monoclonal antibodies as cancer-specific magnetic resonance imaging contrast agents. Australas. Phys. Eng. Sci. Med. 25 (1): 31-38.
16. Hnatowich, D.J., Chils, R.L., Lanteigne, D. and Najafi, A. (1983) The preparation of DTPA coupled antibody radiolabled with metallic radionuclides: an improved method. J. Immunol. Methods 65: 147-157.
17. Shahbazi-Gahrouei, D., Williams, M. and Allen, B.J. (2001) Synthesis and application of Gd-porphyrins as MR imaging agent for cancer detection. Iran. Biomed. J. 5 (2 & 3): 87-95.