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Volumn 74, Issue 2, 2007, Pages 111-124

A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides

Author keywords

Dendritic cells; Entry inhibitors; In vitro model; Microbicides; NNRTI; Sexual HIV transmission

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIGEN P24; CELLULOSE SULFATE; COLCHICINE; DAPIVIRINE; DEXTRAN SULFATE; DS 5000; ENFUVIRTIDE; ETRAVIRINE; MICROBICIDE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; PLACEBO; POLYSTYRENESULFONIC ACID; PRO 2000; PYRIMIDINE DERIVATIVE; R 151694; R 152929; R 153430; RILPIVIRINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

EID: 33947401108     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2006.10.010     Document Type: Article
Times cited : (34)

References (61)
  • 1
    • 24344437154 scopus 로고    scopus 로고
    • HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across an epithelial cell monolayer
    • Alfsen A., Yu H., Magérus-Chatinet A., Schmitt A., and Bomsel M. HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across an epithelial cell monolayer. Mol. Biol. Cell. 16 (2005) 4267-4279
    • (2005) Mol. Biol. Cell. , vol.16 , pp. 4267-4279
    • Alfsen, A.1    Yu, H.2    Magérus-Chatinet, A.3    Schmitt, A.4    Bomsel, M.5
  • 3
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J., and Steinman R.M. Dendritic cells and the control of immunity. Nature 392 (1998) 245-252
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 5
    • 0034488451 scopus 로고    scopus 로고
    • Biologic approaches to the prevention of sexual transmission of human immunodeficiency virus
    • Blocker M.E., and Cohen M.S. Biologic approaches to the prevention of sexual transmission of human immunodeficiency virus. Infect. Dis. Clin. North Am. 14 (2000) 983-999
    • (2000) Infect. Dis. Clin. North Am. , vol.14 , pp. 983-999
    • Blocker, M.E.1    Cohen, M.S.2
  • 7
    • 0026200358 scopus 로고
    • Sorting of plasma membrane proteins in epithelial cells
    • Bomsel M., and Mostov K.E. Sorting of plasma membrane proteins in epithelial cells. Curr. Opin. Cell Biol. 3 (1991) 647-653
    • (1991) Curr. Opin. Cell Biol. , vol.3 , pp. 647-653
    • Bomsel, M.1    Mostov, K.E.2
  • 8
    • 0031023496 scopus 로고    scopus 로고
    • Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier
    • Bomsel M. Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier. Nat. Med. 3 (1997) 42-47
    • (1997) Nat. Med. , vol.3 , pp. 42-47
    • Bomsel, M.1
  • 9
    • 22944476766 scopus 로고    scopus 로고
    • Pathophysiology of HIV-1 in semen: current evidence for compartmentalisation and penetration by antiretroviral drugs
    • Chan D.J. Pathophysiology of HIV-1 in semen: current evidence for compartmentalisation and penetration by antiretroviral drugs. Curr. HIV Res. 3 (2005) 207-222
    • (2005) Curr. HIV Res. , vol.3 , pp. 207-222
    • Chan, D.J.1
  • 11
    • 0034033172 scopus 로고    scopus 로고
    • Development of an in vitro organ culture model to study transmission of HIV-1 in the female genital tract
    • Collins K.B., Patterson B.K., Naus G.J., Landers D.V., and Gupta P. Development of an in vitro organ culture model to study transmission of HIV-1 in the female genital tract. Nat. Med. 6 (2000) 475-479
    • (2000) Nat. Med. , vol.6 , pp. 475-479
    • Collins, K.B.1    Patterson, B.K.2    Naus, G.J.3    Landers, D.V.4    Gupta, P.5
  • 12
    • 0346025452 scopus 로고    scopus 로고
    • Clinical development of microbicides for the prevention of HIV infection
    • D'Cruz O.J., and Uckun F.M. Clinical development of microbicides for the prevention of HIV infection. Curr. Pharm. Des. 10 (2004) 315-336
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 315-336
    • D'Cruz, O.J.1    Uckun, F.M.2
  • 13
    • 0035871775 scopus 로고    scopus 로고
    • Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1
    • Dezzutti C.S., Guenthner P.C., Cummins Jr. J.E., Cabrera T., Marshall J.H., Dillberger A., and Lal R.B. Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1. J. Infect. Dis. 183 (2001) 1204-1213
    • (2001) J. Infect. Dis. , vol.183 , pp. 1204-1213
    • Dezzutti, C.S.1    Guenthner, P.C.2    Cummins Jr., J.E.3    Cabrera, T.4    Marshall, J.H.5    Dillberger, A.6    Lal, R.B.7
  • 14
    • 1642463880 scopus 로고    scopus 로고
    • The evaluation of the local tolerance of vaginal formulations, with or without nonoxynol-9, using the slug mucosal irritation test
    • Dhondt M.M., Adriaens E., and Remon J.P. The evaluation of the local tolerance of vaginal formulations, with or without nonoxynol-9, using the slug mucosal irritation test. Sex. Transm. Dis. 31 (2004) 229-235
    • (2004) Sex. Transm. Dis. , vol.31 , pp. 229-235
    • Dhondt, M.M.1    Adriaens, E.2    Remon, J.P.3
  • 16
    • 0029806126 scopus 로고    scopus 로고
    • Female-controlled methods to prevent sexual transmission of HIV
    • Elias C.J., and Coggins C. Female-controlled methods to prevent sexual transmission of HIV. AIDS 10 Suppl. 3 (1996) S43-S51
    • (1996) AIDS , vol.10 , Issue.SUPPL. 3
    • Elias, C.J.1    Coggins, C.2
  • 18
    • 0028913261 scopus 로고
    • Unidirectional budding of HIV-1 at the site of cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein
    • Fais S., Capobianchi M.R., Abbate I., Castilletti C., Gentile M., Cordiali F.P., Ameglio F., and Dianzani F. Unidirectional budding of HIV-1 at the site of cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein. AIDS 9 (1995) 329-335
    • (1995) AIDS , vol.9 , pp. 329-335
    • Fais, S.1    Capobianchi, M.R.2    Abbate, I.3    Castilletti, C.4    Gentile, M.5    Cordiali, F.P.6    Ameglio, F.7    Dianzani, F.8
  • 19
    • 0034034688 scopus 로고    scopus 로고
    • Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides
    • Greenhead P., Hayes P., Watts P.S., Laing K.G., Griffin G.E., and Shattock R.J. Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides. J. Virol. 74 (2000) 5577-5586
    • (2000) J. Virol. , vol.74 , pp. 5577-5586
    • Greenhead, P.1    Hayes, P.2    Watts, P.S.3    Laing, K.G.4    Griffin, G.E.5    Shattock, R.J.6
  • 21
    • 0032920937 scopus 로고    scopus 로고
    • Infectious human immunodeficiency virus can rapidly penetrate a tight human epithelial barrier by transcytosis in a process impaired by mucosal immunoglobulins
    • Hocini H., and Bomsel M. Infectious human immunodeficiency virus can rapidly penetrate a tight human epithelial barrier by transcytosis in a process impaired by mucosal immunoglobulins. J. Infect. Dis. 179 Suppl. 3 (1999) S448-S453
    • (1999) J. Infect. Dis. , vol.179 , Issue.SUPPL. 3
    • Hocini, H.1    Bomsel, M.2
  • 22
    • 0035038397 scopus 로고    scopus 로고
    • Active and selective transcytosis of cell-free human immunodeficiency virus through a tight polarized monolayer of human endometrial cells
    • Hocini H., Becquart P., Bouhlal H., Chomont N., Ancuta P., Kazatchkine M.D., and Belec L. Active and selective transcytosis of cell-free human immunodeficiency virus through a tight polarized monolayer of human endometrial cells. J. Virol. 75 (2001) 5370-5374
    • (2001) J. Virol. , vol.75 , pp. 5370-5374
    • Hocini, H.1    Becquart, P.2    Bouhlal, H.3    Chomont, N.4    Ancuta, P.5    Kazatchkine, M.D.6    Belec, L.7
  • 23
    • 0034051289 scopus 로고    scopus 로고
    • Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells
    • Hu J., Gardner M.B., and Miller C.J. Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells. J. Virol. 74 (2000) 6087-6095
    • (2000) J. Virol. , vol.74 , pp. 6087-6095
    • Hu, J.1    Gardner, M.B.2    Miller, C.J.3
  • 33
    • 31444443371 scopus 로고    scopus 로고
    • The HEC placebo: designed for "no effect"
    • Microbicides Development Program, London Abstract 02609
    • Moench T.R., Doncel G., and Cone R.A. The HEC placebo: designed for "no effect". Microbicides 2004 Conference Abstracts. Microbicides Development Program, London (2004) 115 Abstract 02609
    • (2004) Microbicides 2004 Conference Abstracts , pp. 115
    • Moench, T.R.1    Doncel, G.2    Cone, R.A.3
  • 35
    • 0030609749 scopus 로고    scopus 로고
    • Heterosexual transmission of human immunodeficiency virus (HIV) in northern California: results from a ten-year study
    • Padian N.S., Shiboski S.C., Glass S.O., and Vittinghoff E. Heterosexual transmission of human immunodeficiency virus (HIV) in northern California: results from a ten-year study. Am. J. Epidemiol. 146 (1997) 350-357
    • (1997) Am. J. Epidemiol. , vol.146 , pp. 350-357
    • Padian, N.S.1    Shiboski, S.C.2    Glass, S.O.3    Vittinghoff, E.4
  • 37
    • 0027397502 scopus 로고
    • Studies of adhesion of lymphocytic cells: implications for sexual transmission of human immunodeficiency virus
    • Pearce-Pratt R., and Phillips D.M. Studies of adhesion of lymphocytic cells: implications for sexual transmission of human immunodeficiency virus. Biol. Reprod. 48 (1993) 431-445
    • (1993) Biol. Reprod. , vol.48 , pp. 431-445
    • Pearce-Pratt, R.1    Phillips, D.M.2
  • 38
    • 0028217413 scopus 로고
    • Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus
    • Pearce-Pratt R., Malamud D., and Phillips D.M. Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus. J. Virol. 68 (1994) 2898-2905
    • (1994) J. Virol. , vol.68 , pp. 2898-2905
    • Pearce-Pratt, R.1    Malamud, D.2    Phillips, D.M.3
  • 39
    • 0001814008 scopus 로고
    • Virological and molecular genetic techniques for studies of established HIV isolates
    • Karn J. (Ed), Oxford University Press, New York
    • Peden K., and Martin M. Virological and molecular genetic techniques for studies of established HIV isolates. In: Karn J. (Ed). A Practical Approach to HIV Virology and Immunology (1995), Oxford University Press, New York 21-45
    • (1995) A Practical Approach to HIV Virology and Immunology , pp. 21-45
    • Peden, K.1    Martin, M.2
  • 40
    • 0028233744 scopus 로고
    • The role of cell-to-cell transmission in HIV infection
    • Phillips D.M. The role of cell-to-cell transmission in HIV infection. AIDS 8 (1994) 719-731
    • (1994) AIDS , vol.8 , pp. 719-731
    • Phillips, D.M.1
  • 43
    • 28144449069 scopus 로고    scopus 로고
    • Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone
    • Pudney J., Quayle A.J., and Anderson D.J. Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone. Biol. Reprod. 73 (2005) 1253-1263
    • (2005) Biol. Reprod. , vol.73 , pp. 1253-1263
    • Pudney, J.1    Quayle, A.J.2    Anderson, D.J.3
  • 44
    • 0030863628 scopus 로고    scopus 로고
    • T lymphocytes and macrophages, but not motile spermatozoa, are a significant source of human immunodeficiency virus in semen
    • Quayle A.J., Xu C., Mayer K.H., and Anderson D.J. T lymphocytes and macrophages, but not motile spermatozoa, are a significant source of human immunodeficiency virus in semen. J. Infect. Dis. 176 (1997) 960-968
    • (1997) J. Infect. Dis. , vol.176 , pp. 960-968
    • Quayle, A.J.1    Xu, C.2    Mayer, K.H.3    Anderson, D.J.4
  • 45
    • 33745158157 scopus 로고
    • A simple method of estimating fifty percent endpoints
    • Reed L.J., and Muench H. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27 (1938) 493-497
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 46
    • 0036891798 scopus 로고    scopus 로고
    • Dendritic cells in innate immune responses against HIV
    • Servet C., Zitvogel L., and Hosmalin A. Dendritic cells in innate immune responses against HIV. Curr. Mol. Med. 2 (2002) 739-756
    • (2002) Curr. Mol. Med. , vol.2 , pp. 739-756
    • Servet, C.1    Zitvogel, L.2    Hosmalin, A.3
  • 47
    • 0345569681 scopus 로고    scopus 로고
    • Inhibiting sexual transmission of HIV-1 infection
    • Shattock R.J., and Moore J.P. Inhibiting sexual transmission of HIV-1 infection. Nat. Rev. Microbiol. 1 (2003) 25-34
    • (2003) Nat. Rev. Microbiol. , vol.1 , pp. 25-34
    • Shattock, R.J.1    Moore, J.P.2
  • 48
    • 0030030573 scopus 로고    scopus 로고
    • Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques
    • Spira A.I., Marx P.A., Patterson B.K., Mahoney J., Koup R.A., Wolinsky S.M., and Ho D.D. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J. Exp. Med. 183 (1996) 215-225
    • (1996) J. Exp. Med. , vol.183 , pp. 215-225
    • Spira, A.I.1    Marx, P.A.2    Patterson, B.K.3    Mahoney, J.4    Koup, R.A.5    Wolinsky, S.M.6    Ho, D.D.7
  • 50
    • 0842343442 scopus 로고    scopus 로고
    • HIV-infected Langerhans cells preferentially transmit virus to proliferating autologous CD4+ memory T cells located within Langerhans cell-T cell clusters
    • Sugaya M., Lore K., Koup R.A., Douek D.C., and Blauvelt A. HIV-infected Langerhans cells preferentially transmit virus to proliferating autologous CD4+ memory T cells located within Langerhans cell-T cell clusters. J. Immunol. 172 (2004) 2219-2224
    • (2004) J. Immunol. , vol.172 , pp. 2219-2224
    • Sugaya, M.1    Lore, K.2    Koup, R.A.3    Douek, D.C.4    Blauvelt, A.5
  • 51
    • 0027378568 scopus 로고
    • Productive infection of a cervical epithelial cell line with human immunodeficiency virus: implications for sexual transmission
    • Tan X., Pearce-Pratt R., and Phillips D.M. Productive infection of a cervical epithelial cell line with human immunodeficiency virus: implications for sexual transmission. J. Virol. 67 (1993) 6447-6452
    • (1993) J. Virol. , vol.67 , pp. 6447-6452
    • Tan, X.1    Pearce-Pratt, R.2    Phillips, D.M.3
  • 53
    • 0036051788 scopus 로고    scopus 로고
    • Considerations and development of topical microbicides to inhibit the sexual transmission of HIV
    • Turpin J.A. Considerations and development of topical microbicides to inhibit the sexual transmission of HIV. Expert Opin. Investig. Drugs 11 (2002) 1077-1097
    • (2002) Expert Opin. Investig. Drugs , vol.11 , pp. 1077-1097
    • Turpin, J.A.1
  • 54
    • 33947376459 scopus 로고    scopus 로고
    • UNAIDS, UNAIDS Global Fact Sheet 22-07-2005, http://www.unaids.org
  • 57
    • 0036402243 scopus 로고    scopus 로고
    • Activity of reverse transcriptase inhibitors in monocyte-derived dendritic cells: a possible in vitro model for postexposure prophylaxis of sexual HIV transmission
    • Van Herrewege Y., Penne L., Vereecken C., Fransen K., van der Groen G., Kestens L., Balzarini J., and Vanham G. Activity of reverse transcriptase inhibitors in monocyte-derived dendritic cells: a possible in vitro model for postexposure prophylaxis of sexual HIV transmission. AIDS Res. Hum. Retroviruses 18 (2002) 1091-1102
    • (2002) AIDS Res. Hum. Retroviruses , vol.18 , pp. 1091-1102
    • Van Herrewege, Y.1    Penne, L.2    Vereecken, C.3    Fransen, K.4    van der Groen, G.5    Kestens, L.6    Balzarini, J.7    Vanham, G.8
  • 59
    • 4644252952 scopus 로고    scopus 로고
    • A series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicides
    • Van Herrewege Y., Vanham G., Michiels J., Fransen K., Kestens L., Andries K., Janssen P., and Lewi P. A series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicides. Antimicrob. Agents Chemother. 48 (2004) 3684-3689
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3684-3689
    • Van Herrewege, Y.1    Vanham, G.2    Michiels, J.3    Fransen, K.4    Kestens, L.5    Andries, K.6    Janssen, P.7    Lewi, P.8
  • 61
    • 0030958022 scopus 로고    scopus 로고
    • Quantification of HIV in semen: correlation with antiviral treatment and immune status
    • Vernazza P.L., Gilliam B.L., Dyer J., Fiscus S.A., Eron J.J., Frank A.C., and Cohen M.S. Quantification of HIV in semen: correlation with antiviral treatment and immune status. AIDS 11 (1997) 987-993
    • (1997) AIDS , vol.11 , pp. 987-993
    • Vernazza, P.L.1    Gilliam, B.L.2    Dyer, J.3    Fiscus, S.A.4    Eron, J.J.5    Frank, A.C.6    Cohen, M.S.7


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