A caspase inhibitor, IDN-6556, ameliorated early hepatic injury in an ex vivo rat model of warm and cold ischemia

Liver Transplantation

Volumn 13, Issue 3, 2007, Pages 361-366

  Hoglen, Niel C ^a   Anselmo, Dean M ^b   Katarl, Masamichi ^b   Kaldas, Marian ^b   Shen, Xiu Da ^b   Valentino, Karen L ^a   Lassman, Charles ^b   Busutill, Ronald W ^b   Kupiec Weglinski, Jerzy W ^b   Farmer, Douglas G ^b  

^a PFIZER INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [(2 TERT BUTYLPHENYLAMINOOXALYL)AMINO]PROPIONYLAMINO] 4 OXO 5 (2,3,5,6 TETRAFLUOROPHENOXY)PENTANOIC ACID; ALANINE AMINOTRANSFERASE; BILE ACID; CASPASE; CASPASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COLD ISCHEMIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYOPRESERVATION; DRUG EFFICACY; ENZYME INHIBITION; EX VIVO STUDY; GRAFT PRESERVATION; GRAFT SURVIVAL; LIVER FUNCTION; LIVER INJURY; LIVER ISCHEMIA; LIVER SINUSOID; LIVER TRANSPLANTATION; MALE; NICK END LABELING; NONHUMAN; PORTAL VEIN BLOOD FLOW; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SCORING SYSTEM; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CASPASES; ENZYME INHIBITORS; MALE; MODELS, ANIMAL; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; PENTANOIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TEMPERATURE; TREATMENT OUTCOME;

EID: 33947399867     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.21016     Document Type: Article

References (29)

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