Genetic stability of recombinant potato virus X virus vectors presenting foreign epitopes

Archives of Virology

Volumn 152, Issue 4, 2007, Pages 805-811

  Uhde Holzem, K ^a   Fischer, R ^a,b   Commandeur, U ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; EPITOPE; HYBRID PROTEIN; VIRUS RNA;

AMINO ACID SEQUENCE; ARTICLE; BEET; BIOSYNTHESIS; CHEMISTRY; COMPARATIVE STUDY; DNA SEQUENCE; GENE DELETION; GENE VECTOR; GENETICS; IMMUNOLOGY; ISOELECTRIC POINT; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; POINT MUTATION; POTEXVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOBACCO; VIROLOGY;

AMINO ACID SEQUENCE; BETA VULGARIS; CAPSID PROTEINS; DNA MUTATIONAL ANALYSIS; EPITOPES; GENETIC VECTORS; ISOELECTRIC POINT; MOLECULAR SEQUENCE DATA; POINT MUTATION; POTEXVIRUS; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; TOBACCO;

BEET NECROTIC YELLOW VEIN VIRUS; BETA VULGARIS SUBSP. VULGARIS; NICOTIANA BENTHAMIANA; POTATO VIRUS X; SOLANUM TUBEROSUM;

EID: 33947387092     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-006-0892-y     Document Type: Article

References (18)

1. LA Baratova NI Grebenshchikov AV Shishkov IA Kashirin JL Radavsky L Jarvekulg M Saarma 1992 The topography of the surface of potato virus X: tritium planigraphy and immunological analysis J Gen Virol 73 229 235
2. D Baulcombe S Chapman S Santa Cruz 1995 Jellyfish green fluorescent protein as a reporter for virus infections Plant J 7 1045 1053
3. M Bendahmane M Koo E Karrer RN Beachy 1999 Display of epitopes on the surface of tobacco mosaic virus: impact of charge and isoelectric point of the epitope on virus-host interactions J Mole Biol 290 9 20
4. S Chapman G Hills J Watts D Baulcombe 1992 Mutational analysis of the coat protein gene of potato virus X: effects on virion morphology and viral pathogenicity Virology 191 223 230
5. U Commandeur R Koenig R Manteuffel L Torrance P Luddecke R Frank 1994 Location, size, and complexity of epitopes on the coat protein of beet necrotic yellow vein virus studied by means of synthetic overlapping peptides Virology 198 282 287
6. SS Cruz S Chapman AG Roberts IM Roberts DA Prior KJ Oparka 1996 Assembly and movement of a plant virus carrying a green fluorescent protein overcoat Proc Natl Acad Sci USA 93 6286 6290
7. SS Cruz AG Roberts DA Prior S Chapman KJ Oparka 1998 Cell-to-cell and phloem-mediated transport of potato virus X. The role of virions Plant Cell 10 495 510
8. ON Fedorkin A Merits J Lucchesi AG Solovyev M Saarma SY Morozov K Makinen 2000 Complementation of the movement-deficient mutations in potato virus X: potyvirus coat protein mediates cell-to-cell trafficking of C-terminal truncation but not deletion mutant of potexvirus coat protein Virology 270 31 42
9. S Hendy ZC Chen H Barker S Santa Cruz S Chapman L Torrance W Cockburn GC Whitelam 1999 Rapid production of single-chain Fv fragments in plants using a potato virus X episomal vector J Immunol Methods 231 137 146
10. B Kimalov A Gal-On R Stav E Belausov T Arazi 2004 Maintenance of coat protein N-terminal net charge and not primary sequence is essential for zucchini yellow mosaic virus systemic infectivity J Gen Virol 85 3421 3430
11. R Koenig JH Tremaine JF Shepard 1978 In situ degradation of the protein chain of Potato virus X at the N- and C-termini J Gen Virol 38 329 337
12. R Koenig L Torrance 1986 Antigenic analysis of potato virus X by means of monoclonal antibodies J Gen Virol 67 2145 2151
13. R Koenig DE Lesemann 1989 Potato virus X, potexvirus group AF Murant BD Harrison AAB descriptions of plant viruses No 354 Association of Applied Biologists Warwick 1 5
14. R Koenig P Lüddecke AM Haeberle 1995 Detection of beet necrotic yellow vein virus strains, variants and mixed infections by examining single-strand conformation polymorphisms of immunocapture RT-PCR products J Gen Virol 76 2051 2055
15. C Marusic P Rizza L Lattanzi C Mancini M Spada F Belardelli E Benvenuto I Capone 2001 Chimeric plant virus particles as immunogens for inducing murine and human immune responses against human immunodeficiency virus type 1 J Virol 75 8434 8439
16. C Porta VE Spall KC Findlay RC Gergerich CE Farrance GP Lomonossoff 2003 Cowpea mosaic virus-based chimaeras. Effects of inserted peptides on the phenotype, host range, and transmissibility of the modified viruses Virology 310 50 63
17. A Tamai T Meshi 2001 Cell-to-cell movement of potato virus X: the role of p12 and p8 encoded by the second and third open reading frames of the triple gene block Mol Plant Microbe Interact 14 1158 1167
18. K Uhde R Fischer U Commandeur 2005 Expression of multiple foreign epitopes presented as synthetic antigens on the surface of potato virus X particles Arch Virol 150 327 340