A sensitive assay for simultaneous determination of plasma concentrations of valganciclovir and its active metabolite ganciclovir by LC/MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 848, Issue 2, 2007, Pages 329-334

  Xu, Hong Rong ^a   Li, Xue Ning ^a   Chen, Wei Li ^a   Liu, Gang Yi ^b   Chu, Nan Nan ^a   Yu, Chen ^b  

^a FUDAN UNIVERSITY   (China)

^b Xuhui District Central Hospital   (China)

Author keywords

Aciclovir; Ganciclovir; LC MS MS; Protein precipitation; Valganciclovir

Indexed keywords

FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; METHANOL; PHARMACOKINETICS; PLASMA (HUMAN); PROTEINS;

ACICLOVIR; GANCICLOVIR; QUADRATIC REGRESSION MODEL; VALGANCICLOVIR;

BIOASSAY;

GANCICLOVIR; REAGENT; SOLVENT; VALGANCICLOVIR;

ACCURACY; ARTICLE; CURVE FITTING; DEVICE; DRUG ANALYSIS; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STRUCTURE; HUMAN; LIQUID CHROMATOGRAPHY; POSITIVE ION ELECTROSPRAY; PRECIPITATION; PRIORITY JOURNAL; REGRESSION ANALYSIS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

ANTIVIRAL AGENTS; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; GANCICLOVIR; HUMANS; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 33947373340     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.10.053     Document Type: Article

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