The number of G residues in the Bacillus subtilis pyrG initially transcribed region governs reiterative transcription-mediated regulation

Journal of Bacteriology

Volumn 189, Issue 5, 2007, Pages 2176-2180

  Elsholz, Alexander K W ^a,b   Jørgensen, Casper Møller ^a   Switzer, Robert L ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BETA GALACTOSIDASE; CYTIDINE; CYTIDINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE SYNTHASE; PYRIMIDINE;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL CELL; DNA SEQUENCE; DNA TEMPLATE; ENZYME ACTIVITY; GENE REPRESSION; GENETIC TRANSCRIPTION; GRAM POSITIVE BACTERIUM; LACTOSE OPERON; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PYRG GENE; TRANSCRIPTION REGULATION;

BACILLUS SUBTILIS; BASE SEQUENCE; CARBON-NITROGEN LIGASES; GENE EXPRESSION REGULATION, BACTERIAL; OPERON; TRANSCRIPTION, GENETIC;

BACILLUS SUBTILIS;

EID: 33947370501     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01611-06     Document Type: Article

References (12)

1. Cheng, Y., S. M. Dylla, and C. L. Turnbough, Jr. 2001. A long T-A tract in the upp initially transcribed region is required for regulation of upp expression by UTP-dependent reiterative transcription in Escherichia coli. J. Bacteriol. 183:221-228.
2. Grandoni, J. A., S. B. Fulmer, V. Brizzio, S. A. Zahler, and J. M. Calvo. 1993. Regions of the Bacillus subtilis ilv-leu operon involved in regulation by leucine. J. Bacteriol. 175:7581-7593.
3. Guo, H. C., and J. W. Roberts. 1990. Heterogeneous initiation due to slip-page at the bacteriophage 82 late promoter in vitro. Biochemistry 27:10702-10709.
4. Jacques, J.-P., and D. Kolakofsky. 1991. Pseudo-templated transcription in prokaryotic and eukaryotic organisms. Genes Dev. 5:707-713.
5. Jergensen, C. M., K. Hammer, and J. Martinussen. 2003. CTP limitation increases expression of CTP synthase in Lactococcus lactis. J. Bacteriol. 185:6562-6574.
6. Leonhardt, H., and J. Alonso. 1988. Construction of a shuttle vector for inducible gene expression in E. coli and B. subtilis. J. Gen. Microbiol. 134:605-609.
7. Martin, C. T., D. K. Muller, and J. E. Coleman. 1988. Processivity in early stages of transcription by T7 RNA polymerase. Biochemistry 27:3966-3974.
8. Meng, Q., and R. L. Switzer. 2001. Regulation of transcription of the Bacillus subtilis pyrG gene encoding cytidine triphosphate synthetase. J. Bacteriol. 183:5513-5522.
9. Meng, Q., and R. L. Switzer. 2002. cis-acting sequences of Bacillus subtilis pyrG mRNA essential for regulation by antitermination. J. Bacteriol. 184:6734-6738.
10. Meng, Q., C. L. Turnbough, Jr., and R. L. Switzer. 2004. Attenuation control of pyrG expression in Bacillus subtilis is mediated by CTP-sensitive reiterative transcription. Proc. Natl. Acad. Sci. USA 101:10943-10948.
11. Xiong, X. F., and W. S. Resnikoff. 1993. Transcriptional slippage during the transcription initiation process at a mutant lac promoter in vivo. J. Mol. Biol. 231:569-580.
12. Zuker, M. 2003. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31:3406-3415.