Effect of mercury, cadmium, nickel, chromium and zinc on kinetic properties of NADPH-cytochrome P450 reductase purified from leaping mullet (Liza saliens)

Toxicology in Vitro

Volumn 21, Issue 3, 2007, Pages 408-416

  Bozcaarmutlu, Azra ^a   Arinç, Emel ^b  

^a ABANT IZZET BAYSAL UNIVERSITY   (Turkey)

^b MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Cadmium; Chromium; Leaping mullet (Liza saliens); Mercury; NADPH cytochrome P450 reductase; Nickel; Noncompetitive inhibition; Zinc

Indexed keywords

CADMIUM; CADMIUM CHLORIDE; CHROMIUM; CHROMIUM CHLORIDE; CYTOCHROME P450; MERCUROUS CHLORIDE; MERCURY; METAL ION; NICKEL; NICKEL CHLORIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; ZINC;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME PURIFICATION; FISH; IC 50; IN VITRO STUDY; NONHUMAN;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; LIVER; METALS, HEAVY; NADPH-FERRIHEMOPROTEIN REDUCTASE; SMEGMAMORPHA; WATER POLLUTANTS, CHEMICAL;

LIZA SALIENS;

EID: 33947357707     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2006.10.002     Document Type: Article

References (39)

1. Acan N.L., and Tezcan E.F. Inhibition-kinetics of sheep brain glutathione-reductase by cadmium ion. Biochemical and Molecular Medicine 54 (1995) 33-37
2. 5. In: Arinç E., Schenkman J.B., and Hodgson E. (Eds). Molecular Aspects of Oxidative Drug Metabolizing Enzymes: Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health (1995), Springer, Heidelberg, Germany 21-45
3. Arinç E., and Celik H. Biochemical characterization of purified beef liver NADPH-cytochrome P450 reductase. Journal of Biochemical and Molecular Toxicology 16 (2002) 286-297
4. Arinç E., and Sen A. Characterization of cytochrome P450 dependent mixed-function oxidase system of Gilthead Seabream (Sparus-Aurata, Sparidae) liver. Comparative Biochemistry and Physiology 104B (1993) 133-139
5. Arinç E., Sen A., and Bozcaarmutlu A. Cytochrome P4501A and associated mixed-function oxidase induction in fish as a biomarker for toxic carcinogenic pollutants in the aquatic environment. Pure and Applied Chemistry 72 (2000) 985-994
6. Black S.D., and Coon M.J. Structural features of liver microsomal NADPH-cytochrome P450 reductase. Journal of Biological Chemistry 257 (1982) 5929-5938
7. Bozcaarmutlu A., and Arinç E. Inhibitory effects of divalent metal ions on liver microsomal 7-ethoxyresorufin O-deethylase (EROD) activity of leaping mullet. Marine Environmental Research 58 (2004) 521-524
8. Casalino E., Calzaretti G., Sblano C., and Landriscina C. Cadmium-dependent enzyme activity alteration is not imputable to lipid peroxidation. Archives of Biochemistry and Biophysics 383 (2000) 288-295
9. Cui Y., Zhu Y.G., Zhai R., Huang Y., Qiu Y., and Liang J. Exposure to metal mixtures and human health impacts in a contaminated area in Nanning, China. Environment International 31 (2005) 784-790
10. Doll R., Morgan L.G., and Speizer F.E. Cancers of the lung and nasal sinuses in nickel workers. British Journal of Cancer 24 (1970) 623-632
11. Gayatri R., Rajaram R., and Ramasami T. Inhibition of collagenase by Cr(III): its relevance to stabilization of collagen. Biochimica et Biophysica Acta 1524 (2000) 228-237
12. Guengerich F.P., Wang P., and Mason P.S. Immunological comparison of rat, rabbit, and human liver NADPH-cytochrome P450 reductase. Biochemistry 20 (1981) 2379-2385
13. Guner S., and Colak A. Effect of divalent metal ions on the microsomal aniline hydroxylase system of rainbow trout. Journal of Biochemical Toxicology 11 (1996) 257-262
14. Gutierrez A., Munro A.W., Grunau A., Wolf R., Scrutton N.S., and Roberts G.C.K. Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding-Relaxation kinetic studies with coenzyme analogues. European Journal of Biochemistry 270 (2003) 2612-2621
15. Hanui M., Iyanagi T., Miller P., Lee T.D., and Shively J.E. Complete amino acid sequence of NADPH-cytochrome P450 reductase from porcine hepatic microsomes. Biochemistry 25 (1986) 7906-7911
16. Huang N.W., Pandey A.V., Agrawal V., Reardon W., Lapunzina P.D., Mowat D., Jabs E.W., Van Vliet G., Sack J., Fluck C.E., and Miller W.L. Diversity and function of mutations in P450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis. American Journal of Human Genetics 76 (2005) 729-749
17. Iscan M.Y., and Arinç E. Comparison of highly purified sheep liver and lung NADPH-cytochrome P450 reductase by the analysis of kinetic and catalytic properties. International Journal of Biochemistry 20 (1988) 1189-1196
18. Iyanagi T. Structure and function of NADPH-cytochrome P450 reductase and nitric oxide synthase reductase domain. Biochemical and Biophysical Research Communications 338 (2005) 520-528
19. Kamataki T., Sugiura M., Yamozoe Y., and Kato R. Purification and properties of cytochrome P450 and NADPH-cytochrome c (P450) reductase from human liver microsomes. Biochemical Pharmacology 28 (1979) 1993-2000
20. Kappus H. Overview of enzyme systems involved in bioreduction of drugs and in redox cycling. Biochemical Pharmacology 35 (1986) 1-6
21. Kim J.S., Ahn T., Yim S.K., and Yun C.H. Differential effect of copper (II) on the cytochrome P450 enzymes and NADPH-cytochrome P450 reductase: Inhibition of cytochrome P450 catalyzed reactions by copper (II) ions. Biochemistry 41 (2002) 9438-9447
22. Klotz A.V., Stegeman J.J., and Walsh C. An aryl hydrocarbon hydroxlating hepatic cytochrome P450 from the marine fish Stenotomus chrysops. Archives of Biochemistry and Biophysics 26 (1983) 578-592
23. Kobayashi S., and Rikans L.E. Kinetic properties of guinea pig liver microsomal NADPH-cytochrome P450 reductase. Comparative Biochemistry and Physiology 77B (1984) 313-318
24. Levesque H.M., Moon T.W., Campbell P.G.C., and Hontela A. Seasonal variation in carbohydrate and lipid metabolism of yellow perch (Perca flavescens) chronically exposed to metals in the field. Aquatic Toxicology 60 (2002) 257-267
25. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the folin phenol reagent. Journal of Biological Chemistry 193 (1951) 265-275
26. Lu A.Y.H. NADPH-dependent cytochrome P450 reductase. In: Arinç E., Schenkman J.B., and Hodgson E. (Eds). Molecular Aspects of Monooxgenases and Bioactivation of Toxic Compounds (1991), Plenum Press, New York 135-147
27. Lu A.Y.H., Junk K.W., and Coon M.J. Resolution of the cytochrome P450 containing omega-hydroxylation system of liver microsomes into three components. Journal of Biological Chemistry 244 (1969) 3714-3721
28. Master B.S.S., Williams C.H., and Kamin H. The preparation and properties of microsomal TPNH-cytochrome c reductase from pig liver. In: Colowick S.P., and Kaplan N.O. (Eds). Methods in Enzymology 10 (1967), Academic Press, New York 565-573
29. Miltyk W., and Palka J. Acetylsalicylic acid prevents nickel-induced collagen biosynthesis in human fibroblasts. Environmental Toxicology and Pharmacology 20 (2005) 501-505
30. Munro A., Noble M., Robledo L., Daff S., and Chapman S. Determination of the redox properties of human NADPH-cytochrome P450 reductase. Biochemistry 40 (2001) 1956-1963
31. Nordberg G.F. Current issues in low-dose cadmium toxicology: nephrotoxicity and carcinogenicity. Environmental Science 4 (1996) 133-147
32. Otto D.M., Henderson C.J., Carrie D., Davey M., Gundersen T.E., Blomhoff R., Adams R.H., Tickle C., and Wolf C.R. Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis. Molecular Cell Biology 23 (2003) 6103-6116
33. Risher J.F., Murray E.H., and Prince G.R. Organic mercury compounds: human exposure and its relevance to public health. Toxicology and Industrial Health 18 (2002) 109-160
34. +3: comparison of the effects of metal ions on choliesterases. Comparative Biochemistry and Physiology 122C (1999) 181-190
35. Sen A., and Arinç E. Purification and characterization of cytochrome P450 reductase from feral leaping mullet (Liza saliens) liver microsomes. Journal of Biochemistry and Molecular Toxicology 12 (1998) 103-113
36. Shen A.L., O'Leary C.B., and Kasper C.B. Association of multiple developmental defects and embryonic lethality with loss of microsomal NADPH-cytochrome P450-oxidoreductase. Journal of Biological Chemistry 277 (2002) 6536-6541
37. Williams D.E., Becker R.R., Potter D.W., Guengerich F.P., and Buhler D.R. Purification and comparative properties of NADPH-cytochrome P450 reductase from rat and rainbow trout: differences in temperature optima between reconstituted and microsomal trout enzymes. Archives of Biochemistry and Biophysics 225 (1983) 55-66
38. Yasukochi Y., Okita R.T., and Masters S.S. Comparison of properties of detergent-solubilized NADPH-cytochrome P450 reductase from pig liver and kidney: immunological, kinetic and reconstitutive properties. Archives of Biochemistry and Biophysics 202 (1980) 491-498
39. 2 and ferrocytochrome c and enzymic determination of extinction coefficients of cytochrome c. Journal of Biological Chemistry 210 (1965) 4509-4514