Oral hyaluronan gel reduces post operative tarsocrural effusion in the yearling Thoroughbred

Handbook of Environmental Chemistry, Volume 5: Water Pollution

Volumn 38, Issue 4, 2006, Pages 375-378

  Bergin, B J ^a,c   Pierce, S W ^a   Bramlage, L R ^a   Stromberg, A ^b  

^a ROOD AND RIDDLE EQUINE HOSPITAL   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c OREGON STATE UNIVERSITY   (United States)

Author keywords

Arthroscopic; Horse; Hyaluronan; Joint effusion; Oral hyaluronan; Osteochondritis dissecans; Tarsocrural; Thoroughbred

Indexed keywords

EQUUS CABALLUS;

HYALURONIC ACID; IMMUNOLOGICAL ADJUVANT;

ANIMAL; ANIMAL DISEASE; ARTHROSCOPY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; GEL; HINDLIMB; HORSE; HORSE DISEASE; METABOLISM; METHODOLOGY; ORAL DRUG ADMINISTRATION; OSTEOCHONDRITIS DISSECANS; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL; SYNOVIAL FLUID; SYNOVIUM;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; ARTHROSCOPY; GELS; HORSE DISEASES; HORSES; HYALURONIC ACID; OSTEOCHONDRITIS DISSECANS; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; SYNOVIAL FLUID; SYNOVIAL MEMBRANE; TARSUS, ANIMAL;

EID: 33947328220     PISSN: 14336863     EISSN: 04251644     Source Type: Book Series    
DOI: 10.2746/042516406777749218     Document Type: Article

References (20)

1. Balazs, E.A., Watson, D., Duff, I.F. and Roseman, S. (1967) Hyaluronic acid in synovial fluid: I. Molecular parameters of hyaluronic acid in normal and arthritic human fluids. Arthritis Rheum. 10, 357-376.
2. Beeman, G.M. and McIlwraith, C.W. (1986) Summary of panel findings In: AQHA Developmental Orthopedic Disease Symposium, Ed: C.W. McIlwraith, American Quarter Horse Association, pp 55-63.
3. Brown, T.J., Alcorn, D. and Fraser, J.R. (1999) Absorption of hyaluronan applied to the surface of intact skin. J. Dermatol. 113, 740-746.
4. Dawes, J., Hodson, B.A. and Pepper, D.S. (1989) The absorption, clearance and metabolic fate of dermatan sulfate administered to man-studies using a radioiodinated derivative. Thromb. Haemost. 62, 945-949.
5. Dawes, J., McLaren, M., Forbes, C., Belch, J.J., Lane, D.A., Bray, B., McEwen, J., Houin, G. and Gianese, F. (1991) The pharmacokinetics of dermatan sulfate MF701 in healthy human volunteers. Br. J. Clin. Pharmacol. 32, 361-366.
6. Engstrom-Laurent, A. (1989) Changes in hyaluronan concentration in tissues and body fluids in disease states. Ciba Found. Symp. 143, 233-40: discussion 240-247, 281-285.
7. Fraser, J.R. and Laurent, T.C. (1989) Turnover and metabolism of hyaluronan. Ciba Found. Symp. 143, 41-53.
8. Hilbert, B.J., Rowley, G. and Antonas, K.N. (1984) Hyaluronic acid concentration in synovial fluid in normal and arthritic joints of horses. Aust. vet. J. 61, 22-24.
9. Howard, R.D. and McIlwraith, C.W. (1996) Hyaluronan and its use in the treatment of equine joint disease. In: Joint Disease in the Horse, Eds: C.W. McIlwraith and G.W. Trotter, W.B. Saunders Co., Philadelphia. pp 257-269.
10. Kawcak, C.E., Frisbie, D.D., Trotter, G.W., McIlwraith, C.W., Gillette, S.M., Powers, B.E. and Walton, R.M. (1997) Effects of intravenous administration of sodium hyaluronate on carpal joints in exercising horses after arthroscopic surgery and osteochondral fragmentation. Am. J. vet. Res. 58, 1132-1140.
11. Laurent, T.C. and Fraser, J.R. (1986) The properties and turnover of hyaluronan. Ciba Found. Symp. 124, 9-29.
12. McIlwraith, C.W. (1993) What is developmental orthopedic disease, osteochondrosis, osteochondritis, metabolic bone disease? Proc. Am. Ass. equine Practnrs. 39, 35-44.
13. McIlwraith, C.W. (1996) General pathobiology of the joint and response to injury. In: Joint Disease in the Horse, Eds: C.W. McIlwraith and G.W. Trotter, W.B. Saunders Co., Philadelphia. pp 40-70.
14. McIlwraith, C.W., Foerner, J.J. and Davis, D.M. (1991) Osteochondritis dissecans of the tarsocrural joint: results of treatment with arthroscopic surgery. Equine vet. J. 23, 155-162.
15. Pirnazar, P., Wolinsky, L., Nachnani, S., Haake, S., Pilloni, A. and Bernard, G.W. (1999) Bacteriostatic effects of hyaluronic acid. J. Periodontal. 70, 370-374.
16. Reed, R.K., Townsley, M.I., Laurent, T.C. and Taylor, A.E. (1992) Hyaluronan flux from cat intestine: changes with lymph flow. Am. J. Physiol. 262 H457-62.
17. Rydell, N.W., Butler, J. and Balazs, E.A. (1970) Hyaluronic acid in synovial fluid: VI. Effect of intra-articular injection of hyaluronic acid on the clinical symptoms of arthritis in track horses. Acta. vet. Scand. 11, 139-155.
18. Salartash, K., Gonze, M.D., Leone-Bay, A., Baughman, R., Sternbergh, W.C. (3rd) and Money, S.R. (1999) Oral low-molecular weight heparin and delivery agent prevents jugular venous thrombosis in the rat. J. vasc. Surg. 30, 526-31.
19. Schauss, A.G., Balogh, L., Polyak, A., Mathe, D., Kiraly, R. and Janoki, G. (2004) Absorption, distribution and excretion of 99mtechnetium labeled hyaluronan after single oral doses in rats and beagle dogs. FASEB. Abstract 129, 4.
20. Silvestro, L., Lanzarotti, E., Marchi, E., Gori, M., Pescador, R., Ferro, L., Milani, M.R., Da Col, R. and Coppini, A. (1994) Human pharmacokinetics of glycosaminoglycans using deuterium-labeled and unlabeled substances: evidence for oral absorption. Semin. Thromb. Hemost. 20, 281-292.