Parabens inhibit human skin estrogen sulfotransferase activity: Possible link to paraben estrogenic effects

Toxicology

Volumn 232, Issue 3, 2007, Pages 248-256

  Prusakiewicz, Jeffery J ^a   Harville, Heather M ^a   Zhang, Yanhua ^a   Ackermann, Chrisita ^a   Voorman, Richard L ^a  

^a PFIZER INC   (United States)

Author keywords

Estrogen; Keratinocyte; Paraben; Skin; Sulfotransferase

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; BUTYL PARABEN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN SULFOTRANSFERASE; ESTRONE; PRASTERONE;

ADULT; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; PRIORITY JOURNAL; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; SULFATION;

CHROMATOGRAPHY, LIQUID; CYTOSOL; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; KERATINOCYTES; LIVER; PARABENS; PRESERVATIVES, PHARMACEUTICAL; SKIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SULFOTRANSFERASES; SULFUR; TANDEM MASS SPECTROMETRY;

ANIMALIA;

EID: 33947326124     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.01.010     Document Type: Article

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