-
1
-
-
0036773971
-
FTY720: Targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity
-
Brinkmann V, Lynch KR. FTY720: Targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity. Curr Opin Immunol 2002; 14: 569.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 569
-
-
Brinkmann, V.1
Lynch, K.R.2
-
2
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann V, Davies MD, Heise CE, et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem 2002; 277: 21453.
-
(2002)
J Biol Chem
, vol.277
, pp. 21453
-
-
Brinkmann, V.1
Davies, M.D.2
Heise, C.E.3
-
3
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine 1-phosphate receptor agonists
-
Mandala S, Hajdu R, Bergstrom J, et al. Alteration of lymphocyte trafficking by sphingosine 1-phosphate receptor agonists. Science 2002; 296: 346.
-
(2002)
Science
, vol.296
, pp. 346
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
-
4
-
-
0036205659
-
First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients
-
Budde K, Schmouder RL, Brunkhorst R, et al. First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients. J Am Soc Nephrol 2002; 13: 1073.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1073
-
-
Budde, K.1
Schmouder, R.L.2
Brunkhorst, R.3
-
5
-
-
0142040141
-
Pharmacodynamics, pharmacokinetics and safety of multiple doses of FTY720 in stable renal transplant patients: A multicenter randomized, placebo-controlled, phase I study
-
Kahan BD, Karlix JL, Ferguson RM, et al. Pharmacodynamics, pharmacokinetics and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter randomized, placebo-controlled, phase I study. Transplantation 2003; 76: 1079.
-
(2003)
Transplantation
, vol.76
, pp. 1079
-
-
Kahan, B.D.1
Karlix, J.L.2
Ferguson, R.M.3
-
6
-
-
20544456156
-
FTY720, a novel immunomodulator: Efficacy and safety results from the first phase 2A study in de novo renal transplantation
-
Tedesco-Silva H, Mourad G, Kahan BD, et al. FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation. Transplantation 2005; 79: 1553.
-
(2005)
Transplantation
, vol.79
, pp. 1553
-
-
Tedesco-Silva, H.1
Mourad, G.2
Kahan, B.D.3
-
7
-
-
33745800873
-
FTY720/cyclosporine regimens in de novo renal transplantation: A 1-year dose-finding study
-
Mulgaonkar S, Tedesco H, Oppenheimer F, et al. FTY720/cyclosporine regimens in de novo renal transplantation: a 1-year dose-finding study. Am J Transplant 2006; 6: 1848.
-
(2006)
Am J Transplant
, vol.6
, pp. 1848
-
-
Mulgaonkar, S.1
Tedesco, H.2
Oppenheimer, F.3
-
8
-
-
33745927144
-
FTY720: Placebo-controlled study of the effect of cardiac rate and rhythm in healthy subjects
-
Schmouder R, Serra D, Wang Y, et al. FTY720: placebo-controlled study of the effect of cardiac rate and rhythm in healthy subjects. J Clin Pharmacol 2006; 46: 895.
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 895
-
-
Schmouder, R.1
Serra, D.2
Wang, Y.3
-
9
-
-
33947316304
-
-
Presented at the European Neurological Society, Vienna, Austria, June 18-22
-
Kappos L, Radue EW, Antel J, et al. FTY720 in relapsing MS: results of a double-blind placebo-controlled trial with a novel oral immunomodulator. Presented at the European Neurological Society, Vienna, Austria, June 18-22, 2005.
-
(2005)
FTY720 in relapsing MS: Results of a double-blind placebo-controlled trial with a novel oral immunomodulator
-
-
Kappos, L.1
Radue, E.W.2
Antel, J.3
-
10
-
-
3042743990
-
FTY720: Sphingosine 1-phosphate receptor-1 (S1P1) in the control of lymphocyte egress and endothelial barrier function
-
Brinkmann V, Cyster JG, Hla T. FTY720: sphingosine 1-phosphate receptor-1 (S1P1) in the control of lymphocyte egress and endothelial barrier function. Am J Transplant 2004; 4: 1019.
-
(2004)
Am J Transplant
, vol.4
, pp. 1019
-
-
Brinkmann, V.1
Cyster, J.G.2
Hla, T.3
-
11
-
-
14644408845
-
The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I
-
Koyrakh L, Roman MI, Brinkmann V, Wickman K. The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I. Am J Transplant 2005; 5: 529.
-
(2005)
Am J Transplant
, vol.5
, pp. 529
-
-
Koyrakh, L.1
Roman, M.I.2
Brinkmann, V.3
Wickman, K.4
-
12
-
-
0141567617
-
Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3)
-
Licht T, Tsirulnikov L, Reuveni H, et al. Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3). Blood 2003; 102: 2099.
-
(2003)
Blood
, vol.102
, pp. 2099
-
-
Licht, T.1
Tsirulnikov, L.2
Reuveni, H.3
-
13
-
-
2442679391
-
The immunosuppressant FTY720 downregulates sphingosine 1-phosphate G-protein-coupled receptors
-
Graler MH, Goetzl EJ. The immunosuppressant FTY720 downregulates sphingosine 1-phosphate G-protein-coupled receptors. FASEB J 2004; 18: 551.
-
(2004)
FASEB J
, vol.18
, pp. 551
-
-
Graler, M.H.1
Goetzl, E.J.2
|