Quantification by real-time PCR of the magnitude and duration of leucocyte-associated viraemia in horses infected with neuropathogenic vs. non-neuropathogenic strains of EHV-1

Handbook of Environmental Chemistry, Volume 5: Water Pollution

Volumn 38, Issue 3, 2006, Pages 252-257

  Allen, G P ^a   Breathnach, C C ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Cell associated viraemia; Equine herpesvirus 1; Herpesvirus myeloencephalopathy; Horse; Neurological disease; Quantitative PCR

Indexed keywords

EQUID HERPESVIRUS 1; EQUIDAE; EQUUS CABALLUS; HERPESVIRIDAE; HUMAN HERPESVIRUS 1;

VIRUS DNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; EQUINE HERPES VIRUS; FEMALE; HERPES VIRUS INFECTION; HORSE; HORSE DISEASE; ISOLATION AND PURIFICATION; MALE; METHODOLOGY; MONONUCLEAR CELL; PATHOGENICITY; POLYMERASE CHAIN REACTION; VIREMIA; VIROLOGY;

ANIMALS; DNA, VIRAL; FEMALE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, EQUID; HORSE DISEASES; HORSES; LEUKOCYTES, MONONUCLEAR; MALE; POLYMERASE CHAIN REACTION; VIREMIA;

EID: 33947309055     PISSN: 14336863     EISSN: 04251644     Source Type: Book Series    
DOI: 10.2746/042516406776866453     Document Type: Article

References (24)

1. Allen, G.P. and Bryans, J.T. (1986) Molecular epizootiology, pathogenesis, and prophylaxis of equine herpesvirus-1 infections. P rog. vet. Microbiol. Immunol. 2, 78-144.
2. Allen, G.P., Kydd, J.H., Slater, J.D. and Smith, K.C. (2004) Equid herpesvirus 1 (EHV-1) and equid herpesvirus 4 (EHV-4) infections. In: Infectious Diseases of Livestock, Eds: J.A.W. Coetzer and R.C. Tustin, Oxford Press, Cape Town. pp 829-859.
3. Batra, S.K., Jain, N.C. and Tiwara, S.C. (1982) Isolation and characterization of EHV-1 herpesvirus associated with paralysis in equines. Indian J. anim. Sci. 52, 671-677.
4. Bitsch, V. and Dam, A. (1971) Nervous disturbances in horses in relation to infection with equine rhinopneumonitis virus. Acta vet. Scand. 12, 134-136.
5. Borchers, K. and Slater, J. (1993) A nested PCR for the detection and differentiation of EHV-1 and EHV-4. J. Virol. Meth. 45, 331-336.
6. Breathnach, C.C., Yeargan, M.R., Sheoran, A.S. and Allen, G.P. (2001) The mucosal humoral immune response of the horse to infective challenge and vaccination with equine herpesvirus-1 antigens. Equine vet. J. 33, 651-657.
7. Bryans, J.T. and Allen, G.P. (1989) Herpesviral diseases of the horse. In: Herpesvirus Diseases of Cattle, Horses and Pigs, Ed: G. Wittmann, Kluwer, Boston. pp 176-229.
8. Charlton, K.M., Mitchell, D., Girard, A. and Corner, A.H. (1976) Meningoencephalomyelitis in horses associated with equine herpesvirus 1 infection. Vet. Pathol. 13, 59-68.
9. Crabb, B.S., Drummer, H.E., Ruebel, G.H., Macpherson, C.M., Browning, G.F. and Studdert, M.J. (1995) A type specific, serological test to distinguish antibodies to equine herpesviruses 4 and 1. Arch. Virol. 140, 245-258.
10. Dinter, Z. and Klingeborn, B. (1976) Serological study of an outbreak of paresis due to equine herpesvirus-1. Vet. Rec. 99, 10-12.
11. Donaldson, M.T. and Sweeney, C.R. (1997) Equine herpes myeloencephalopathy. Comp. cont. Educ. pract. Vet. 19, 864-871.
12. Edington, N., Bridges, C.G. and Patel, J.R. (1986) Endothelial cell infection and thrombosis in paralysis caused by equid herpesvirus-1: equine stroke. Arch. Virol. 90, 111-124.
13. Greenwood, R.S. and Simpson, A.B. (1980) Clinical report of a paralytic syndrome affecting stallions, mares and foals on a Thoroughbred studfarm. Equine vet. J. 12, 113-117.
14. Jackson, T.A. and Kendrick, J.W. (1971) Paralysis of horses associated with equine herpesvirus 1 infection. J. Am. vet. med. Ass. 158, 1351-1357.
15. Kohn, C.W. and Fenner, W.R. (1987) Equine herpes myeloencephalopathy. Vet. Clin. N. Am.: Equine Pract. 3, 405-419.
16. Little, P.B. and Thorsen, J. (1976) Disseminated necrotizing myeloencephalitis: a herpes-associated neurological disease of horses. Vet. Pathol. 13, 161-171.
17. T method. Methods 25, 402-408.
18. Mumford, J.A., Hannant, D., Jessett, D.M., O'Neill, T., Smith, K.C. and Ostlund, E.N. (1994) Abortigenic and neurological disease caused by experimental infection with equid herpesvirus-1. In: Equine Infectious Diseases VII, Eds: W. Plowright and H. Nakajima, R&W Publications, Newmarket. pp 261-275.
19. Nugent, J., Birch-Machin, I., Smith, K.C., Mumford, J.A., Swann, Z., Newton, R., Allen, G.P.and Davis-Poynter, N. (2003) DNA polymerase sequence variation is a marker of virulence for equine herpesvirus type 1. In: Proceedings of the 3rd International Veterinary Vaccine and Diagnostics Conference, Guelph, Canada. p 71. [Abstr.]
20. Nugent, J., Birch-Machin, I., Smith, K.C., Mumford, J.A., Swann, Z., Newton, R., Allen, G.P. and Davis-Poynter, N. (2006) Analysis of equine herpesvirus type 1 strain variation reveals a point mutation of the DNA polymerase strongly associated with neuropathogenic versus non-neuropathogenic disease outbreaks. J. Virol. (In Press).
21. Platt, H., Singh, H. and Whitwell, K.E. (1980) Pathological observations on an outbreak of paralysis in broodmares. Equine vet. J. 12, 118-126.
22. Saxegaard, F. (1966) Isolation and identification of equine rhinopneumonitis virus from cases of abortion and paralysis. Nord. vet. Med. 18, 504-516.
23. Whitwell, K.E. and Blunden, A.S. (1992) Pathological findings in horses dying during an outbreak of the paralytic form of Equid herpesvirus type 1 (EHV-1) infection. Equine vet. J. 24, 13-19.
24. Wilson, W.D. (1997) Equine herpesvirus 1 myeloencephalopathy. Vet. Clin. N. Am.: Equine Pract. 13, 53-72.