Two N-linked glycans are required to maintain the transport activity of the bile salt export pump (ABCB11) in MDCK II cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 292, Issue 3, 2007, Pages

  Mochizuki, Kaori ^a   Kagawa, Tatehiro ^a   Numari, Asano ^a   Harris, Matthew J ^b   Itoh, Johbu ^a   Watanabe, Norihito ^a   Mine, Tetsuya ^a   Arias, Irwin M ^b,c  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Bile acid; Bile secretion; Cholestasis

Indexed keywords

ABC TRANSPORTER; ATP BINDING CASSETTE TRANSPORTER B11; BAFILOMYCIN A1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BILE SALT; BILE SALT EXPORT PUMP; GLYCAN DERIVATIVE; TAUROCHOLIC ACID; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GLYCOSYLATION; INTRACELLULAR TRANSPORT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT, ACTIVE; CELL LINE; CYSTEINE PROTEINASE INHIBITORS; DOGS; EPITHELIAL CELLS; GLYCOSYLATION; KINETICS; LEUPEPTINS; LUMINESCENT PROTEINS; MUTATION; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; POLYSACCHARIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECOMBINANT FUSION PROTEINS; SYMPORTERS; TAUROCHOLIC ACID; TRANSFECTION; TUNICAMYCIN;

EID: 33947307145     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00415.2006     Document Type: Article

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