-
1
-
-
0037078985
-
Gene therapy: A tragic setback
-
Check, E. Gene therapy: a tragic setback. Nature 2002, 420, 116-118.
-
(2002)
Nature
, vol.420
, pp. 116-118
-
-
Check, E.1
-
2
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina, S.; Von Kalle, C.; Schmidt, M. et al.. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 2003, 302, 415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
3
-
-
0003008343
-
Synthetic DNA delivery system
-
Luo, D.; Saltzman, W. M. Synthetic DNA delivery system. Nat. Biotechnol 2000, 18, 33-37.
-
(2000)
Nat. Biotechnol
, vol.18
, pp. 33-37
-
-
Luo, D.1
Saltzman, W.M.2
-
4
-
-
0031159393
-
Nonviral strategies for gene therapy
-
Felgner, P. L. Nonviral strategies for gene therapy. Sci. Am. 1997, 276, 102-106.
-
(1997)
Sci. Am
, vol.276
, pp. 102-106
-
-
Felgner, P.L.1
-
5
-
-
0032473410
-
Polylysine-based transfection systems utilizing receptor-mediated delivery
-
Zauner, W.; Ogris, M.; Wagner, E. Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv. Drug Delivery Rev. 1998, 30, 98-113.
-
(1998)
Adv. Drug Delivery Rev
, vol.30
, pp. 98-113
-
-
Zauner, W.1
Ogris, M.2
Wagner, E.3
-
6
-
-
0035980982
-
Design and gene delivery activity of modified polyethylenimines
-
Kircheis, R.; Wightman, L.; Wagner, E. Design and gene delivery activity of modified polyethylenimines. Adv. Drug Delivery Rev. 2001, 53, 341-358.
-
(2001)
Adv. Drug Delivery Rev
, vol.53
, pp. 341-358
-
-
Kircheis, R.1
Wightman, L.2
Wagner, E.3
-
7
-
-
0032479769
-
Cationic Liposomes for Gene Therapy
-
Miller, A. D. Cationic Liposomes for Gene Therapy. Angew. Chem., Int. Ed. Engl. 1998, 37, 1768-1785.
-
(1998)
Angew. Chem., Int. Ed. Engl
, vol.37
, pp. 1768-1785
-
-
Miller, A.D.1
-
8
-
-
0033609001
-
Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery
-
Godbey, W. T.; Wu, K. K.; Mikos, A. G. Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery. Proc. Natl. Acad. Sci. USA 1999, 96, 5177-5181.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5177-5181
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
9
-
-
0343307124
-
Cationic lipids used in gene transfer
-
Zabner, J. Cationic lipids used in gene transfer. Adv. Drug Delivery Rev. 1997, 27, 17-28.
-
(1997)
Adv. Drug Delivery Rev
, vol.27
, pp. 17-28
-
-
Zabner, J.1
-
10
-
-
0042311016
-
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery
-
Anderson, D. G.; Lynn, D. M.; Langer, R. Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. Angew. Chem., Int. Ed. Engl. 2003, 42, 3153-3158.
-
(2003)
Angew. Chem., Int. Ed. Engl
, vol.42
, pp. 3153-3158
-
-
Anderson, D.G.1
Lynn, D.M.2
Langer, R.3
-
11
-
-
0038293017
-
Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery
-
Akinc, A.; Lynn, D. M.; Anderson, D. G. et al. Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. J. Am. Chem. Soc. 2003, 125, 5316-5323.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 5316-5323
-
-
Akinc, A.1
Lynn, D.M.2
Anderson, D.G.3
-
12
-
-
17644401347
-
Cross-linked small polyethylenimines: While still nontoxic, deliver DNA efficiently to mammalian cells in vitri and in vivo
-
Thomas, M.; Ge, Q.; Lu, J. J. et al. Cross-linked small polyethylenimines: while still nontoxic, deliver DNA efficiently to mammalian cells in vitri and in vivo. Pharmaceutical Research 2005, 22, 373-380.
-
(2005)
Pharmaceutical Research
, vol.22
, pp. 373-380
-
-
Thomas, M.1
Ge, Q.2
Lu, J.J.3
-
13
-
-
0037161323
-
Biodegradable poly(ethylenimine) for plasmid DNA delivery
-
Ahn, C. H.; Chae, S. Y.; Bae, Y. H. et al. Biodegradable poly(ethylenimine) for plasmid DNA delivery. J. Controlled Release 2002, 80, 273-282.
-
(2002)
J. Controlled Release
, vol.80
, pp. 273-282
-
-
Ahn, C.H.1
Chae, S.Y.2
Bae, Y.H.3
-
14
-
-
0345688743
-
Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity
-
Jon, S.; Anderson, D. G.; Langer, R. Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity. Biomacromolecules 2003, 4, 1759-1762.
-
(2003)
Biomacromolecules
, vol.4
, pp. 1759-1762
-
-
Jon, S.1
Anderson, D.G.2
Langer, R.3
-
15
-
-
8644275490
-
A polymer library approach to suicide gene therapy for cancer
-
Anderson, D. G.; Peng, W.; Akinc, A. et al. A polymer library approach to suicide gene therapy for cancer. Proc. Natl. Acad.Sci. USA. 2004, 101, 16028-16033.
-
(2004)
Proc. Natl. Acad.Sci. USA
, vol.101
, pp. 16028-16033
-
-
Anderson, D.G.1
Peng, W.2
Akinc, A.3
-
16
-
-
0036740007
-
Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and non-toxic gene delivery carrier
-
Lim, Y.-B.; Kim, S.-M.; Suh, H. et al. Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and non-toxic gene delivery carrier. Bioconjug. Chem. 2002, 13, 952-957.
-
(2002)
Bioconjug. Chem
, vol.13
, pp. 952-957
-
-
Lim, Y.-B.1
Kim, S.-M.2
Suh, H.3
-
17
-
-
0141569730
-
A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery
-
Forrest, M. L.; Koerber, J. T.; Pack, D. W. A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery. Bioconjugate Chem. 2003, 14, 934-940.
-
(2003)
Bioconjugate Chem
, vol.14
, pp. 934-940
-
-
Forrest, M.L.1
Koerber, J.T.2
Pack, D.W.3
-
18
-
-
0032811354
-
Poly-(ethylenimine) and its role in gene delivery
-
Godbey, W. T.; Wu, K. K.; Mikos, A. G. Poly-(ethylenimine) and its role in gene delivery. J. Controlled Release 1999, 60, 149-160.
-
(1999)
J. Controlled Release
, vol.60
, pp. 149-160
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
19
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
Boussif, O.; Lezoualc'h, F.; Zanta, M. A. et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc. Natl. Acad. Sci. USA. 1995, 92, 7297-7301.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
-
20
-
-
0033166095
-
In Vivo Delivery to Tumors of DNA Complexed with Linear Polyethylenimine
-
Coll, J. L.; Chollet, P.; Brambilla, E. et al. In Vivo Delivery to Tumors of DNA Complexed with Linear Polyethylenimine. Hum. Gene Ther. 1999, 10, 1659-1666.
-
(1999)
Hum. Gene Ther
, vol.10
, pp. 1659-1666
-
-
Coll, J.L.1
Chollet, P.2
Brambilla, E.3
-
21
-
-
3242807724
-
Gene transfer with modified polyethylenimines
-
Antoine, Kichler. Gene transfer with modified polyethylenimines. J Gene Med. 2004, 6, S3-S10.
-
(2004)
J Gene Med
, vol.6
-
-
Antoine, K.1
-
22
-
-
0029799791
-
A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: Polyethylenimine
-
Abdallah, B.; Hassan, A.; Benoist, C. et al. A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine. Hum. Gene Ther 1996, 7, 1947-1954.
-
(1996)
Hum. Gene Ther
, vol.7
, pp. 1947-1954
-
-
Abdallah, B.1
Hassan, A.2
Benoist, C.3
-
23
-
-
0032625105
-
Poly(4-hydroxy-L-proline ester): Low-Temperature Polycondensation and Plasmid DNA Complexation
-
Putnam, D.; Langer, R. Poly(4-hydroxy-L-proline ester): Low-Temperature Polycondensation and Plasmid DNA Complexation. Macromolecules 1999, 32, 3658-3662.
-
(1999)
Macromolecules
, vol.32
, pp. 3658-3662
-
-
Putnam, D.1
Langer, R.2
-
24
-
-
0030462391
-
Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold
-
Boussif, O.; Zanta, M. A.; Behr, J.-P. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther. 1996, 3, 1074-1080.
-
(1996)
Gene Ther
, vol.3
, pp. 1074-1080
-
-
Boussif, O.1
Zanta, M.A.2
Behr, J.-P.3
-
25
-
-
0034609633
-
Poly(ethylenimine)-mediated transfection: A new paradigm for gene delivery
-
Godbey, W. T.; Barry, M. A.; Saggau, P. et al. Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery. J. Biomed. Mater. Res. 2000, 51, 321-328.
-
(2000)
J. Biomed. Mater. Res
, vol.51
, pp. 321-328
-
-
Godbey, W.T.1
Barry, M.A.2
Saggau, P.3
-
26
-
-
0031860769
-
Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system
-
Goula, D.; Remy, JS; Erbacher, P. et al. Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system. Gene Ther. 1998, 5, 712-717.
-
(1998)
Gene Ther
, vol.5
, pp. 712-717
-
-
Goula, D.1
Remy, J.S.2
Erbacher, P.3
-
27
-
-
0031788165
-
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
-
Ogris, M.; Steinlein, P.; Kursa, M. et al. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther. 1998, 5, 1425-1433.
-
(1998)
Gene Ther
, vol.5
, pp. 1425-1433
-
-
Ogris, M.1
Steinlein, P.2
Kursa, M.3
-
28
-
-
0037069319
-
Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells
-
Thomas, M.; Klibanov, A. M. Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proc. Natl. Acad. Sci. USA 2002, 99, 14640-14645.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14640-14645
-
-
Thomas, M.1
Klibanov, A.M.2
-
29
-
-
0032892476
-
Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
-
Godbey, W. T.; Wu, K. K.; Mikos, A. G. Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J. Biomed. Mater. Res. 1999, 45, 268-275.
-
(1999)
J. Biomed. Mater. Res
, vol.45
, pp. 268-275
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
30
-
-
14044272234
-
Structure/property studies of polymeric gene delivery using a library of poly(β-amino esters)
-
Daniel, G.; Anderson, A. A.; Naushad, H. Structure/property studies of polymeric gene delivery using a library of poly(β-amino esters). Mol. Ther. 2005, 11, 426-434.
-
(2005)
Mol. Ther
, vol.11
, pp. 426-434
-
-
Daniel, G.1
Anderson, A.A.2
Naushad, H.3
-
31
-
-
28444471561
-
-
Zhong, Zhiyuan ; Yan, Song ; Johan, F. J. et al. A versatile family of degradable non-viral gene carriers based on hyperbranched poly(ester amine)s. J. Control. Release 2005, 109, 317-329.
-
Zhong, Zhiyuan ; Yan, Song ; Johan, F. J. et al. A versatile family of degradable non-viral gene carriers based on hyperbranched poly(ester amine)s. J. Control. Release 2005, 109, 317-329.
-
-
-
-
32
-
-
0344926354
-
Functional in vivo gene transfer into the myofibers of adult skeletal muscle
-
Massimo, Don; Marco, Sandri; Katia, Rossini et al. Functional in vivo gene transfer into the myofibers of adult skeletal muscle. Biochem Bioph Res Co 2003, 312, 1132-1138.
-
(2003)
Biochem Bioph Res Co
, vol.312
, pp. 1132-1138
-
-
Massimo, D.1
Marco, S.2
Katia, R.3
-
33
-
-
33847211797
-
Polyethylenimine- complexed Plasmid Particles Targeting Focal Adhesion Kinase Function as Melanoma Tumor Therapeutics
-
in press
-
Li, Shufeng; Dong, Wei; Zong, Yiwei et al. Polyethylenimine- complexed Plasmid Particles Targeting Focal Adhesion Kinase Function as Melanoma Tumor Therapeutics. Mol. Ther. 2007, in press
-
(2007)
Mol. Ther
-
-
Li, S.1
Dong, W.2
Zong, Y.3
-
34
-
-
0037437033
-
Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: Comparision of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
-
Kunath, K.; Harpe, A. V; Fisher, D. et al. Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparision of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. J. Control. Release 2003, 89, 113-125.
-
(2003)
J. Control. Release
, vol.89
, pp. 113-125
-
-
Kunath, K.1
Harpe, A.V.2
Fisher, D.3
-
35
-
-
19544362720
-
Mechanistic studies on aggregation of polyethylenimine-DNA complexes and its prevention
-
Sharma, V. K.; Thomas, M.; Klibanov, A. M. Mechanistic studies on aggregation of polyethylenimine-DNA complexes and its prevention. Biotechnology and Bioengineering 2005, 90, 614-620.
-
(2005)
Biotechnology and Bioengineering
, vol.90
, pp. 614-620
-
-
Sharma, V.K.1
Thomas, M.2
Klibanov, A.M.3
-
36
-
-
0034821014
-
Accelerated discovery of synthetic transfection vectors: Parallel synthesis and screening of a degradable polymer library
-
Lynn, D. M.; Anderson, D. G.; Putnam, D. et al. Accelerated discovery of synthetic transfection vectors: Parallel synthesis and screening of a degradable polymer library. J. Am. Chem. Soc. 2001, 123, 8155-8156.
-
(2001)
J. Am. Chem. Soc
, vol.123
, pp. 8155-8156
-
-
Lynn, D.M.1
Anderson, D.G.2
Putnam, D.3
-
37
-
-
0034623567
-
Degradable poly(β-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA
-
Lynn, D. M.; Langer, R. Degradable poly(β-amino esters): synthesis, characterization, and self-assembly with plasmid DNA. J. Am. Chem. Soc. 2000, 122, 10761-10768.
-
(2000)
J. Am. Chem. Soc
, vol.122
, pp. 10761-10768
-
-
Lynn, D.M.1
Langer, R.2
|