Superporous pellicular agarose-glass composite particle for protein adsorption

Biochemical Engineering Journal

Volumn 34, Issue 2, 2007, Pages 99-106

  Zhou, Xin ^a,c   Sun, Yan ^b   Liu, Zheng ^a  

^a TSINGHUA UNIVERSITY   (China)

^b TIANJIN UNIVERSITY   (China)

^c BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

Adsorption; Composite particle; Diffusion; Mass transfer; Protein; Superporous pellicular

Indexed keywords

ADSORPTION; DIFFUSION; GLASS; MASS TRANSFER; POROUS MATERIALS; PROTEINS;

COMPOSITE PARTICLES; POROGENIC AGENT; PROTEIN ADSORPTION; SUPERPOROUS PELLICULAR STRUCTURE;

COMPOSITE MATERIALS;

2 DIETHYLAMINOETHANOL; AGAROSE; BOVINE SERUM ALBUMIN; GLASS; WATER OIL CREAM;

ADSORPTION CHROMATOGRAPHY; ARTICLE; COMPOSITE MATERIAL; CROSS LINKING; DENSITY; DISSOLUTION; MICROSCOPY; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; STRUCTURE ANALYSIS;

BOVINAE;

EID: 33947304464     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2006.09.018     Document Type: Article

References (20)

1. Lucy C.A. Recent advances in ion chromatography: A perspective. J. Chromatogr. A 739 (1996) 3-13
2. Jungbauer A. Chromatographic media for bioseparation. J. Chromatogr. A 1065 (2005) 3-12
3. Hjorth R. Expanded-bed adsorption in industrial bioprocessing: recent developments. Trends Biotechnol. 15 (1997) 230-235
4. Chang Y.K., and Chase H.A. Development of operating conditions for protein purification using expanded-bed techniques: the effect of the degree of bed expansion on adsorption performance. Biotechnol. Bioeng. 49 (1996) 512-526
5. Ferreira G.N.M., Cabral J.M.S., and Prazeres D.M.F. Anion exchange purification of plasmid DNA using expanded-bed adsorption. Bioseparation 9 (2000) 1-6
6. Bruce L.J., and Chase H.A. Hydrodynamics and adsorption behavior within an expanded-bed adsorption column studied using in-bed sampling. Chem. Eng. Sci. 56 (2001) 3149-3162
7. Pai A., Gondkar S., and Lali A. Enhanced performance of expended bed chromatography on rigid superporous adsorbent matrix. J. Chromatogr. A 867 (2000) 113-130
8. Willoughby N.A., Hjorth R., and Hooker N.T. Experimental measurement of particle size distribution and voidage in an expanded-bed adsorption system. Biotechnol. Bioeng. 69 (2000) 648-653
9. Zhou X., Shi Q.H., Bai S., and Sun Y. Dense pellicular agarose-glass beads for expanded bed application: fabrication and characterization for effective protein adsorption. Biochem. Eng. J. 18 (2004) 81-88
10. Palsson E., Gustavsson P.-E., and Larsson P.-O. Pellicular expanded bed matrix suitable for high flow rates. J. Chromatogr. A 878 (2000) 17-25
11. Gustavsson P.-E., and Larsson P.-O. Superporous agarose, a new material for chromatography. J. Chromatogr. A 734 (1996) 231-240
12. Shi Q.H., Zhou X., and Sun Y. A novel superporous agarose medium for high-speed protein chromatography. Biotechnol. Bioeng. 92 (2005) 643-651
13. Jamila T., and Denis L. Relationship between reduction of complement activation by polysaccharide surfaces bearing diethylaminoethyl groups and their degree of substitution. Biomaterials 16 (1995) 1081-1088
14. Yu Y.H., and Sun Y. Macroporous poly(glycidyl methacrylate-triallyl isocyanurate-divinylbenzene) matrix as an anion-exchange resin for protein adsorption. J. Chromatogr. A 855 (1999) 129-136
15. Xue B., and Sun Y. Protein adsorption equilibria and kinetics to a poly(vinyl alcohol)-based magnetic affinity support. J. Chromatogr. A 921 (2001) 109-119
16. Horstmann B.J., and Chase H.A. Modeling the affinity adsorption of mmunoglobulin G to protein an immobilised to agarose matrices. Chem. Eng. Res. Des. 67 (1989) 243-254
17. Kirkland J.J., Truszkowski F.A., Dilks Jr. C.H., and Engel G.S. Superficially porous silica microspheres for fast high-performance liquid chromatography of macromolecules. J. Chromatogr. A 890 (2000) 3-13
18. Tong X.D., and Sun Y. Particle size and density distributions of two dense matrices in an expanded system. J. Chromatogr. A 977 (2002) 173-183
19. Sun Y., Pacek A.W., Nienow A.W., and Lyddiatt A. Fabrication and characterisation of a novel pellicular adsorbent customized for the effective fluidised bed adsorption of protein products. Biotechnol. Bioprocess. Eng. 6 (2001) 419-425
20. Gustavsson P.-E., and Larsson P.-O. Continuous superporous agarose beds in radial flow column. J. Chromatogr. A 925 (2001) 69-78