Bystander effects induced by serum from survivors of the Chernobyl accident

Experimental Hematology

Volumn 35, Issue 4 SUPPL., 2007, Pages 55-63

  Marozik, Pavel ^a   Mothersill, Carmel ^b   Seymour, Colin B ^b   Mosse, Irma ^b   Melnov, Sergeyi ^b  

^a Sakarov University   (Belarus)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MELANIN; MELATONIN; RADIOPROTECTIVE AGENT;

ARTICLE; BLOOD SAMPLING; BYSTANDER EFFECT; CELL CULTURE; CELL IMMORTALIZATION; CELL VIABILITY; CHERNOBYL ACCIDENT; CONTROL GROUP; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LABORATORY; MALE; MICRONUCLEUS; POPULATION; PRIORITY JOURNAL; RADIATION EXPOSURE; REACTOR; SERUM; SURVIVOR; TOXICITY; WORKER;

BYSTANDER EFFECT; CELL LINE, TRANSFORMED; CELL SURVIVAL; CHERNOBYL NUCLEAR ACCIDENT; FREE RADICAL SCAVENGERS; HUMANS; MELANINS; MELATONIN; MICRONUCLEUS TESTS; RADIATION INJURIES; RADIATION-PROTECTIVE AGENTS; SERUM; SURVIVORS; TIME FACTORS;

EID: 33947288617     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.01.029     Document Type: Article

References (24)

1. Morgan W.F. Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro. [review]. Radiat Res 159 (2003) 567-580
2. Little J.B., and Morgan W.F. Genetic instability. Special issue. Oncogene (2003) 13
3. Lorimore S.A., and Wright E.G. Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury? A review. Int J Radiat Biol 79 (2003) 15-25
4. Mothersill C., and Seymour C.B. Radiation-induced bystander effects-implications for cancer. [review]. Nat Rev Cancer 4 (2004) 158-164
5. Goh K., and Sumner H. Breaks in normal human chromosomes: are they induced by a transferable substance in the plasma of persons exposed to total-body irradiation?. Radiat Res 35 (1968) 171-181
6. Hollowell Jr. J.G., and Littlefield L.G. Chromosome damage induced by plasma of x-rayed patients: an indirect effect of x-ray. Proc Soc Exp Biol Med 129 (1968) 240-244
7. Pant G.S., and Kamada N. Chromosome aberrations in normal leukocytes induced by the plasma of exposed individuals. Hiroshima J Med Sci 26 (1977) 149-154
8. Murphy J.B., and Morton J. Action of serum from x-rayed animals on lymphoid cells in vitro. J Exp Med XX11 (1915) 800
9. Faguet G.B., Reichard S.M., and Welter D.A. Radiation-induced clastogenic plasma factors. Cancer Genet Cytogenet 12 (1984) 73-83
10. Emerit I. Reactive oxygen species, chromosome mutation, and cancer: possible role of clastogenic factors in carcinogenesis. [review]. Free Radic Biol Med 16 (1994) 99-109
11. Mothersill C., and Seymour C. Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells. Int J Radiat Biol 71 (1997) 421-427
12. Mothersill C., and Seymour C. Radiation-induced bystander effects: past history and future directions. [review]. Radiat Res 155 (2001) 759-767
13. Mothersill C., Lyng F., Seymour C., Maguire P., Lorimore S., and Wright E. Genetic factors influencing bystander signaling in murine bladder epithelium after low-dose irradiation in vivo. Radiat Res 163 (2005) 391-399
14. Mothersill C., Bucking C., Smith R.W., et al. Communication of radiation-induced bystander signals between fish in vivo. Environ Sci Technol 40 (2006) 6859-6864
15. Watson G.E., Lorimore S.A., Macdonald D.A., and Wright E.G. Chromosomal instability in unirradiated cells induced in vivo by a bystander effect of ionizing radiation. Cancer Res 60 (2000) 5608-5611
16. Shao C., Folkard M., Michael B.D., and Prise K.M. Bystander signaling between glioma cells and fibroblasts targeted with counted particles. Int J Cancer 116 (2005) 45-51
17. Seymour C.B., Mothersill C., Mooney R., Moriarty M., and Tipton K.F. Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity. Br J Cancer 89 (2003) 1979-1986
18. Mosse I., Marozik P., Seymour C., and Mothersill C. The effect of melanin on the bystander effect in human keratinocytes. Mutat Res 597 (2006) 133-137
19. Emerit I., Oganesian N., Arutyunian R., et al. Oxidative stress-related clastogenic factors in plasma from Chernobyl liquidators: protective effects of antioxidant plant phenols, vitamins and oligoelements. Mutat Res 377 (1997) 239-246
20. Emerit I., Oganesian N., Sarkisian T., et al. Clastogenic factors in the plasma of Chernobyl accident recovery workers: anticlastogenic effect of Ginkgo biloba extract. Radiat Res 144 (1995) 198-205
21. Environmental Consequences of the Chernobyl Accident and Their Remediation: Twenty Years of Experience: Report of the UN Chernobyl Forum. Expert Group "Environment" (EGE), August 2005.
22. Pirisi L., Creek K.E., Doniger J., and DiPaolo J.A. Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA. Carcinogenesis 9 (1988) 1573-1579
23. Melnov S.B. Biological dosimetry: theoretical and practical aspects. Minsk 191 (2002)
24. Sevan'kaev A.V., Lloyd D.C., Edwards A.A., et al. A cytogenetic follow-up of some highly irradiated victims of the Chernobyl accident. Radiat Prot Dosimetry 113 (2005) 152-161