-
1
-
-
0036840510
-
The renin-angiotensin system as a risk factor and therapeutic target for cardiovascular and renal disease
-
Volpe M, Savoia C, De Paolis P, et at. The renin-angiotensin system as a risk factor and therapeutic target for cardiovascular and renal disease. J Am Soc Nephrol. 2002;13(suppl 3):S173-S178.
-
(2002)
J Am Soc Nephrol
, vol.13
, Issue.SUPPL. 3
-
-
Volpe, M.1
Savoia, C.2
De Paolis, P.3
et at4
-
2
-
-
0033398149
-
The renin-angiotensin-aldosterone system: A specific target for hypertension management
-
Weir MR, Dzau VJ. The renin-angiotensin-aldosterone system: a specific target for hypertension management. Am J Hypertens. 1999; 12(12 pt 3):205S-213S.
-
(1999)
Am J Hypertens
, vol.12
, Issue.12 PART 3
-
-
Weir, M.R.1
Dzau, V.J.2
-
3
-
-
4644249249
-
The tissue renin-angiotensin-aldosterone system in diabetes mellitus
-
Hanes DS, Nahar A, Weir MR. The tissue renin-angiotensin-aldosterone system in diabetes mellitus. Curr Hypertens Rep. 2004;6:98-105.
-
(2004)
Curr Hypertens Rep
, vol.6
, pp. 98-105
-
-
Hanes, D.S.1
Nahar, A.2
Weir, M.R.3
-
4
-
-
0037409237
-
The adipose-tissue renin-angiotensin-aldosterone system: Role in the metabolic syndrome?
-
Engeli S, Schling P, Gorzelniak K, et al. The adipose-tissue renin-angiotensin-aldosterone system: role in the metabolic syndrome? Int J Biochem Cell Biol. 2003;35:807-825.
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 807-825
-
-
Engeli, S.1
Schling, P.2
Gorzelniak, K.3
-
5
-
-
22144477948
-
Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus: Results of prospectively designed overviews of randomized trials. The Blood Pressure Lowering Treatment Trialists' Collaboration
-
Turnbull F, Neal B, Algert C, et al. Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus: results of prospectively designed overviews of randomized trials. The Blood Pressure Lowering Treatment Trialists' Collaboration. Arch Intern Med. 2005;165:1410-1419.
-
(2005)
Arch Intern Med
, vol.165
, pp. 1410-1419
-
-
Turnbull, F.1
Neal, B.2
Algert, C.3
-
6
-
-
0242654867
-
Effects of different blood-pressure-lowering regimens on major cardiovascular events: Results of prospectively-designed overviews of randomised trials
-
Blood Pressure Lowering Treatment Trialists' Collaboration
-
Blood Pressure Lowering Treatment Trialists' Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet. 2003; 362:1527-1535.
-
(2003)
Lancet
, vol.362
, pp. 1527-1535
-
-
-
7
-
-
0034688194
-
-
Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting- enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342:145-1S3.
-
Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting- enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342:145-1S3.
-
-
-
-
8
-
-
0042330455
-
Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: Randomised, double-blind, placebo-controlled, multicentre trial. The EUROPA Study
-
Fox KM. Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial. The EUROPA Study. Lancet. 2003;362: 782-788.
-
(2003)
Lancet
, vol.362
, pp. 782-788
-
-
Fox, K.M.1
-
9
-
-
19644400972
-
Angiotensin-converting-enzyme Inhibition in stable coronary artery disease
-
Braunwald E, Domanski MJ, Fowler SE, et al. Angiotensin-converting-enzyme Inhibition in stable coronary artery disease. N Engl J Med. 2004;351:2058-2068.
-
(2004)
N Engl J Med
, vol.351
, pp. 2058-2068
-
-
Braunwald, E.1
Domanski, M.J.2
Fowler, S.E.3
-
10
-
-
7744231805
-
Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure. The CAMELOT study: A randomized controlled trial
-
Nissen SE, Tuzcu EM, Libby P, et al. Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure. The CAMELOT study: a randomized controlled trial. JAMA. 2004;292: 2217-2225.
-
(2004)
JAMA
, vol.292
, pp. 2217-2225
-
-
Nissen, S.E.1
Tuzcu, E.M.2
Libby, P.3
-
11
-
-
33746797303
-
Effects of normal, pre-hypertensive and hypertensive blood pressure levels on progression of coronary atherosclerosis
-
Sipahi I, Tuzcu EM, Schoenhagen P, et al. Effects of normal, pre-hypertensive and hypertensive blood pressure levels on progression of coronary atherosclerosis. J Am Coll Cardiol. 2006; 48:833-838.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 833-838
-
-
Sipahi, I.1
Tuzcu, E.M.2
Schoenhagen, P.3
-
12
-
-
0023266532
-
Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
-
The CONSENSUS Trial Study Group
-
The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med. 1987;316:1429-1435.
-
(1987)
N Engl J Med
, vol.316
, pp. 1429-1435
-
-
-
13
-
-
0035818884
-
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
-
Cohn JN, Tognoni G. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med. 2001;345:1667-1675.
-
(2001)
N Engl J Med
, vol.345
, pp. 1667-1675
-
-
Cohn, J.N.1
Tognoni, G.2
-
14
-
-
0042410539
-
Effects of candesartan on mortality and morbidity in patients with chronic heart failure. The CHARM-Overall Programme
-
Pfeffer MA, Swedberg K, Granger CB, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure. The CHARM-Overall Programme. Lancet. 2003;362: 759-766.
-
(2003)
Lancet
, vol.362
, pp. 759-766
-
-
Pfeffer, M.A.1
Swedberg, K.2
Granger, C.B.3
-
15
-
-
0026786643
-
Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: Results of the Survival and Ventricular Enlargement trial. The SAVE Investigators
-
Pfeffer MA, Braunwald E, Moye LA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement trial. The SAVE Investigators. N Engl J Med. 1992;327:669-677.
-
(1992)
N Engl J Med
, vol.327
, pp. 669-677
-
-
Pfeffer, M.A.1
Braunwald, E.2
Moye, L.A.3
-
16
-
-
0242490542
-
Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
-
Pfeffer MA, McMurray JJ, Velazquez EJ, et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med. 2003;349:1893-1906.
-
(2003)
N Engl J Med
, vol.349
, pp. 1893-1906
-
-
Pfeffer, M.A.1
McMurray, J.J.2
Velazquez, E.J.3
-
17
-
-
0027517659
-
The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group
-
Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med. 1993;329:1456-1462.
-
(1993)
N Engl J Med
, vol.329
, pp. 1456-1462
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Bain, R.P.3
Rohde, R.D.4
-
18
-
-
0035922447
-
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
-
Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001;345:851-860.
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
-
19
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345:861-869.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
de Zeeuw, D.3
-
20
-
-
0036176161
-
K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification and stratification
-
National Kidney Foundation
-
National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis. 2002;39:S1-S266.
-
(2002)
Am J Kidney Dis
, vol.39
-
-
-
21
-
-
28844504752
-
Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: Systematic review and meta-analysis
-
Casas JP, Chua W, Loukogeorgakis S, et al. Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis. Lancet. 2005;366:2026-2033.
-
(2005)
Lancet
, vol.366
, pp. 2026-2033
-
-
Casas, J.P.1
Chua, W.2
Loukogeorgakis, S.3
-
22
-
-
0028306578
-
Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease
-
Collins R, MacMahon S. Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease. Br Med Bull. 1994;50:272-298.
-
(1994)
Br Med Bull
, vol.50
, pp. 272-298
-
-
Collins, R.1
MacMahon, S.2
-
23
-
-
0035968623
-
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemlc attack
-
PROGRESS Investigators
-
PROGRESS Investigators. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemlc attack. Lancet. 2001;358:1033-1041.
-
(2001)
Lancet
, vol.358
, pp. 1033-1041
-
-
-
24
-
-
20444427156
-
Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: Principal results of a prospective randomized controlled study (MOSES)
-
Schrader J, Luders S, Kulschewski A, et al. Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES). Stroke. 2005;36:1218-1226.
-
(2005)
Stroke
, vol.36
, pp. 1218-1226
-
-
Schrader, J.1
Luders, S.2
Kulschewski, A.3
-
25
-
-
0037160968
-
Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint Reduction in Hypertension study (LIFE): A randomised trial against atenolol
-
Dahlof B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint Reduction in Hypertension study (LIFE): a randomised trial against atenolol. Lancet. 2002;359:995-1003.
-
(2002)
Lancet
, vol.359
, pp. 995-1003
-
-
Dahlof, B.1
Devereux, R.B.2
Kjeldsen, S.E.3
-
26
-
-
0030872646
-
The Losartan Intervention For Endpoint Reduction (LIFE) in Hypertension study, rationale, design, and methods. The LIFE Study Group
-
Dahlof B, Devereux R, de Faire U, et al. The Losartan Intervention For Endpoint Reduction (LIFE) in Hypertension study, rationale, design, and methods. The LIFE Study Group. Am J Hypertens. 1997;10(7 pt 1):705-713.
-
(1997)
Am J Hypertens
, vol.10
, Issue.7 PART 1
, pp. 705-713
-
-
Dahlof, B.1
Devereux, R.2
de Faire, U.3
-
27
-
-
0037434556
-
A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly
-
Wing LM, Reid CM, Ryan P, et al. A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly. N Engl J Med. 2003;348:583-592.
-
(2003)
N Engl J Med
, vol.348
, pp. 583-592
-
-
Wing, L.M.1
Reid, C.M.2
Ryan, P.3
-
28
-
-
24644443331
-
Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial
-
Dahlof B, Sever PS, Poulter NR, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet. 2005;366:895-906.
-
(2005)
Lancet
, vol.366
, pp. 895-906
-
-
Dahlof, B.1
Sever, P.S.2
Poulter, N.R.3
-
29
-
-
33645518432
-
Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: Principal results of the Conduit Artery Function Evaluation (CAFÉ) study. CAFÉ Investigators, Anglo-Scandinavian Cardiac Outcomes Trial Investigators, CAFÉ Steering Committee and Writing Committee
-
Williams B, Lacy PS, Thom SM, et al. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFÉ) study. CAFÉ Investigators, Anglo-Scandinavian Cardiac Outcomes Trial Investigators, CAFÉ Steering Committee and Writing Committee. Circulation. 2006;113: 1213-1225.
-
(2006)
Circulation
, vol.113
, pp. 1213-1225
-
-
Williams, B.1
Lacy, P.S.2
Thom, S.M.3
-
30
-
-
2942635317
-
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: The VALUE randomised trial
-
Julius S, Kjeldsen SE, Weber M, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet. 2004;363:2022-2031.
-
(2004)
Lancet
, vol.363
, pp. 2022-2031
-
-
Julius, S.1
Kjeldsen, S.E.2
Weber, M.3
-
31
-
-
0028278186
-
Pharmacology of renin inhibitors and their application to the treatment of hypertension
-
Wood JM, Cumin F, Maibaum J. Pharmacology of renin inhibitors and their application to the treatment of hypertension. Pharmacol Ther. 1994;61:325-344.
-
(1994)
Pharmacol Ther
, vol.61
, pp. 325-344
-
-
Wood, J.M.1
Cumin, F.2
Maibaum, J.3
-
32
-
-
0042661157
-
Structure-based design of aliskiren, a novel orally effective renin inhibitor
-
Wood JM, Maibaum J, Rahuel J, et al. Structure-based design of aliskiren, a novel orally effective renin inhibitor. Biochem Biophys Res Commun. 2003;308:698-705.
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 698-705
-
-
Wood, J.M.1
Maibaum, J.2
Rahuel, J.3
-
33
-
-
0036372173
-
Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): Comparison with enalapril
-
Nussberger J, Wuerzner G, Jensen C, Brunner HR. Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril. Hypertension. 2002; 39:E1-E8.
-
(2002)
Hypertension
, vol.39
-
-
Nussberger, J.1
Wuerzner, G.2
Jensen, C.3
Brunner, H.R.4
-
34
-
-
0347479295
-
Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren
-
Stanton A, Jensen C, Nussberger J, O'Brien E. Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren. Hypertension. 2003;42:1137-1143.
-
(2003)
Hypertension
, vol.42
, pp. 1137-1143
-
-
Stanton, A.1
Jensen, C.2
Nussberger, J.3
O'Brien, E.4
-
35
-
-
14844363404
-
Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients
-
Gradman AH, Schmieder RE, Lins RL, et al. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation. 2005;111: 1012-1018.
-
(2005)
Circulation
, vol.111
, pp. 1012-1018
-
-
Gradman, A.H.1
Schmieder, R.E.2
Lins, R.L.3
-
36
-
-
9644287897
-
-
1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol. 2004;15:3126-3133.
-
1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol. 2004;15:3126-3133.
-
-
-
-
37
-
-
33644806751
-
Expanding the definition and classification of hypertension
-
Giles TD, Berk BC, Black HR, et al. Expanding the definition and classification of hypertension. J Clin Hypertens. 2005;7:505-512.
-
(2005)
J Clin Hypertens
, vol.7
, pp. 505-512
-
-
Giles, T.D.1
Berk, B.C.2
Black, H.R.3
-
38
-
-
3543038818
-
Trial of Preventing Hypertension: Design and 2-year progress report
-
Julius S, Nesbitt S, Egan B, et al. Trial of Preventing Hypertension: design and 2-year progress report. Hypertension. 2004;44:146-151.
-
(2004)
Hypertension
, vol.44
, pp. 146-151
-
-
Julius, S.1
Nesbitt, S.2
Egan, B.3
-
39
-
-
22844441621
-
Is low-risk hypertension fact or fiction? Cardiovascular risk profile in the TROPHY study
-
Nesbitt SD, Julius S, Leonard D, et al. Is low-risk hypertension fact or fiction? Cardiovascular risk profile in the TROPHY study. Am J Hypertens. 2005;18:980-985.
-
(2005)
Am J Hypertens
, vol.18
, pp. 980-985
-
-
Nesbitt, S.D.1
Julius, S.2
Leonard, D.3
-
40
-
-
33645860811
-
The Trial of Preventing Hypertension (TROPHY) Study Investigators. Feasibility of treating prehypertension with an angiotensin-receptor blocker
-
Julius S, Nesbitt SD, Egan BM, et al. The Trial of Preventing Hypertension (TROPHY) Study Investigators. Feasibility of treating prehypertension with an angiotensin-receptor blocker. N Engl J Med. 2006;354:1685-1697.
-
(2006)
N Engl J Med
, vol.354
, pp. 1685-1697
-
-
Julius, S.1
Nesbitt, S.D.2
Egan, B.M.3
|