메뉴 건너뛰기




Volumn 66, Issue 4, 2007, Pages 466-474

Metabolic effects of growth hormone (GH) replacement in children and adolescents with severe isolated GH deficiency due to a GHRH receptor mutation

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; GROWTH HORMONE RELEASING FACTOR RECEPTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HUMAN GROWTH HORMONE; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 33947266119     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2007.02753.x     Document Type: Article
Times cited : (27)

References (45)
  • 1
    • 0028944463 scopus 로고
    • Clinical aspects of growth hormone deficiency in adults
    • De Boer, H., Blok, G.J. & Van Der Veen, E.A. (1995) Clinical aspects of growth hormone deficiency in adults. Endocrine Reviews, 16, 63-86.
    • (1995) Endocrine Reviews , vol.16 , pp. 63-86
    • De Boer, H.1    Blok, G.J.2    Van Der Veen, E.A.3
  • 2
    • 0036315757 scopus 로고    scopus 로고
    • Body composition, IGF-I and IGFBP-3 concentrations as outcome measures in severely GH-deficient (GHD) patients after childhood GH treatment: A comparison with adult onset GHD patients
    • Attanasio, A.F., Howell, S., Bates, P.C., Frewer, P., Chipman, J., Blum, W.F. & Shalet, S.M. (2002) Body composition, IGF-I and IGFBP-3 concentrations as outcome measures in severely GH-deficient (GHD) patients after childhood GH treatment: a comparison with adult onset GHD patients. Journal of Clinical Endocrinology and Metabolism, 87, 3368-3372.
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , pp. 3368-3372
    • Attanasio, A.F.1    Howell, S.2    Bates, P.C.3    Frewer, P.4    Chipman, J.5    Blum, W.F.6    Shalet, S.M.7
  • 4
    • 0033305652 scopus 로고    scopus 로고
    • Discontinuation of growth hormone (GH) treatment: Metabolic effects in GH-deficient and GH-sufficient adolescent patients compared with control subjects. Swedish Study Group for Growth Hormone Treatment in Children
    • Johannsson, G., Albertsson-Wikland, K. & Bengtsson, B.A. (1999) Discontinuation of growth hormone (GH) treatment: metabolic effects in GH-deficient and GH-sufficient adolescent patients compared with control subjects. Swedish Study Group for Growth Hormone Treatment in Children. Journal of Clinical Endocrinology and Metabolism, 84, 4516-4524.
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , pp. 4516-4524
    • Johannsson, G.1    Albertsson-Wikland, K.2    Bengtsson, B.A.3
  • 5
    • 0034458045 scopus 로고    scopus 로고
    • Continuation of growth hormone (GH) replacement in GH-deficient patients during transition from childhood to adulthood: A two-year placebo-controlled study
    • Vahl, N., Juul, A., Jorgensen, J.O., Orskov, H., Skakkebaek, N.E. & Christiansen, J.S. (2000) Continuation of growth hormone (GH) replacement in GH-deficient patients during transition from childhood to adulthood: a two-year placebo-controlled study. Journal of Clinical Endocrinology and Metabolism, 85, 1874-1881.
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , pp. 1874-1881
    • Vahl, N.1    Juul, A.2    Jorgensen, J.O.3    Orskov, H.4    Skakkebaek, N.E.5    Christiansen, J.S.6
  • 8
    • 23044447026 scopus 로고    scopus 로고
    • Limited efficacy of growth hormone (GH) during transition of GH-deficient patients from adolescence to adulthood: A phase III multicenter, double-blind, randomized two-year trial
    • Mauras, N., Pescovitz, O.H., Allada, V., Messig, M., Wajnrajch, M.P. & Lippe, B. (2005) Limited efficacy of growth hormone (GH) during transition of GH-deficient patients from adolescence to adulthood: a phase III multicenter, double-blind, randomized two-year trial. Journal of Clinical Endocrinology and Metabolism, 90, 3946-3955.
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , pp. 3946-3955
    • Mauras, N.1    Pescovitz, O.H.2    Allada, V.3    Messig, M.4    Wajnrajch, M.P.5    Lippe, B.6
  • 10
    • 0030788016 scopus 로고    scopus 로고
    • Boot, A.M., Engels, M.A., Boerma, G.J., Krenning, E.P. & De Muinck Keizer-Schrama, S.M. (1997) Changes in bone mineral density, body composition, and lipid metabolism during growth hormone (GH) treatment in children with GH deficiency. Journal of Clinical Endocrinology and Metabolism, 82, 2423-2428.
    • Boot, A.M., Engels, M.A., Boerma, G.J., Krenning, E.P. & De Muinck Keizer-Schrama, S.M. (1997) Changes in bone mineral density, body composition, and lipid metabolism during growth hormone (GH) treatment in children with GH deficiency. Journal of Clinical Endocrinology and Metabolism, 82, 2423-2428.
  • 11
    • 9144249636 scopus 로고    scopus 로고
    • Serum homocysteine concentrations in children with growth hormone (GH) deficiency before and after 12 months GH replacement
    • Esposito, V., Di Biase, S., Lettiero, T., Labella, D., Simeone, R. & Salerno, M. (2004) Serum homocysteine concentrations in children with growth hormone (GH) deficiency before and after 12 months GH replacement. Clinical Endocrinology, 61, 607-611.
    • (2004) Clinical Endocrinology , vol.61 , pp. 607-611
    • Esposito, V.1    Di Biase, S.2    Lettiero, T.3    Labella, D.4    Simeone, R.5    Salerno, M.6
  • 12
    • 0023232583 scopus 로고
    • Effect of growth hormone on serum lipoproteins in growth hormone deficiency
    • Gacs, G. & Romics, L. (1987) Effect of growth hormone on serum lipoproteins in growth hormone deficiency. Experimental Clinical Endocrinology, 90, 227-231.
    • (1987) Experimental Clinical Endocrinology , vol.90 , pp. 227-231
    • Gacs, G.1    Romics, L.2
  • 14
    • 0031763971 scopus 로고    scopus 로고
    • Long-term prospective study of body composition and lipid profiles during and after growth hormone (GH) treatment in children with GH deficiency: Gender-specific metabolic effects
    • Kuromaru, R., Kohno, H., Ueyama, N., Hassan, H.M., Honda, S. & Hara, T. (1998) Long-term prospective study of body composition and lipid profiles during and after growth hormone (GH) treatment in children with GH deficiency: gender-specific metabolic effects. Journal of Clinical Endocrinology and Metabolism, 83, 3890-3896.
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , pp. 3890-3896
    • Kuromaru, R.1    Kohno, H.2    Ueyama, N.3    Hassan, H.M.4    Honda, S.5    Hara, T.6
  • 15
    • 0029006928 scopus 로고
    • Beneficial effect of growth hormone on atherogenic risk in children with growth hormone deficiency
    • Kohno, H., Ueyama, N., Yanai, S., Ukaji, K. & Honda, S. (1995) Beneficial effect of growth hormone on atherogenic risk in children with growth hormone deficiency. Journal of Pediatrics, 126, 953-955.
    • (1995) Journal of Pediatrics , vol.126 , pp. 953-955
    • Kohno, H.1    Ueyama, N.2    Yanai, S.3    Ukaji, K.4    Honda, S.5
  • 16
    • 0018574486 scopus 로고
    • Serum cholesterol and triglycerides in children with growth hormone deficiency
    • Winter, R.J., Thompson, R.G. & Green, O.C. (1979) Serum cholesterol and triglycerides in children with growth hormone deficiency. Metabolism, 28, 1244-1249.
    • (1979) Metabolism , vol.28 , pp. 1244-1249
    • Winter, R.J.1    Thompson, R.G.2    Green, O.C.3
  • 18
    • 0030410827 scopus 로고    scopus 로고
    • Body composition, atherogenic risk factors and apolipoproteins following growth hormone treatment
    • Hassan, H.M., Kohno, H., Kuromaru, R., Honda, S. & Ueda, K. (1996) Body composition, atherogenic risk factors and apolipoproteins following growth hormone treatment. Acta Paediatrica, 85, 899-901.
    • (1996) Acta Paediatrica , vol.85 , pp. 899-901
    • Hassan, H.M.1    Kohno, H.2    Kuromaru, R.3    Honda, S.4    Ueda, K.5
  • 19
    • 0033381321 scopus 로고    scopus 로고
    • Growth hormone treatment down-regulates serum leptin levels in children independent of changes in body mass index
    • Elimam, A., Lindgren, A.C., Norgren, S., Kamel, A., Skwirut, C., Bang, P. & Marcus, C. (1999) Growth hormone treatment down-regulates serum leptin levels in children independent of changes in body mass index. Hormone Research, 52, 66-72.
    • (1999) Hormone Research , vol.52 , pp. 66-72
    • Elimam, A.1    Lindgren, A.C.2    Norgren, S.3    Kamel, A.4    Skwirut, C.5    Bang, P.6    Marcus, C.7
  • 20
    • 26944466258 scopus 로고    scopus 로고
    • Effect of growth hormone therapy and puberty on bone and body composition in children with idiopathic short stature and growth hormone deficiency
    • Hogler, W., Briody, J., Moore, B., Lu, P.W. & Cowell, C.T. (2005) Effect of growth hormone therapy and puberty on bone and body composition in children with idiopathic short stature and growth hormone deficiency. Bone, 37, 642-650.
    • (2005) Bone , vol.37 , pp. 642-650
    • Hogler, W.1    Briody, J.2    Moore, B.3    Lu, P.W.4    Cowell, C.T.5
  • 21
    • 0026748796 scopus 로고
    • Changes in body composition of patients with subnormal spontaneous secretion of growth hormone, during the first year of treatment with growth hormone
    • Vaisman, N., Zadik, Z., Shamai, Y., Franklin, L. & Dukhan, R. (1992) Changes in body composition of patients with subnormal spontaneous secretion of growth hormone, during the first year of treatment with growth hormone. Metabolism, 41, 483-486.
    • (1992) Metabolism , vol.41 , pp. 483-486
    • Vaisman, N.1    Zadik, Z.2    Shamai, Y.3    Franklin, L.4    Dukhan, R.5
  • 24
    • 0032748444 scopus 로고    scopus 로고
    • Serum leptin and body composition in children with familial GH deficiency (GHD) due to a mutation in the growth hormone-releasing hormone (GHRH) receptor
    • De, A.B.E.S., Gill, M.S., De Freitas, M.E., Magalhaes, M.M., Souza, A.H., Aguiar-Oliveira, M.H. & Clayton, P.E. (1999) Serum leptin and body composition in children with familial GH deficiency (GHD) due to a mutation in the growth hormone-releasing hormone (GHRH) receptor. Clinical Endocrinology, 51, 559-564.
    • (1999) Clinical Endocrinology , vol.51 , pp. 559-564
    • De, A.B.E.S.1    Gill, M.S.2    De Freitas, M.E.3    Magalhaes, M.M.4    Souza, A.H.5    Aguiar-Oliveira, M.H.6    Clayton, P.E.7
  • 27
    • 0029756177 scopus 로고    scopus 로고
    • Lipids, risk factors and ischaemic heart disease
    • Castelli, W.P. (1996) Lipids, risk factors and ischaemic heart disease. Atherosclerosis, 124, S1-S9.
    • (1996) Atherosclerosis , vol.124
    • Castelli, W.P.1
  • 29
    • 0026740186 scopus 로고
    • Body fat estimations by electrical impedance and infra-red interactance
    • Brodie, D.A. & Eston, R.G. (1992) Body fat estimations by electrical impedance and infra-red interactance. International Journal of Sports Medicine, 13, 319-325.
    • (1992) International Journal of Sports Medicine , vol.13 , pp. 319-325
    • Brodie, D.A.1    Eston, R.G.2
  • 30
    • 0034754984 scopus 로고    scopus 로고
    • The potential of near infrared interactance for predicting body composition in children
    • Fuller, N.J., Dewit, O. & Wells, J.C. (2001) The potential of near infrared interactance for predicting body composition in children. European Journal of Clinical Nutrition, 55, 967-972.
    • (2001) European Journal of Clinical Nutrition , vol.55 , pp. 967-972
    • Fuller, N.J.1    Dewit, O.2    Wells, J.C.3
  • 31
    • 33947262825 scopus 로고
    • Hainline, A, Karon, J. & Lippel, K, eds , 2nd edn. US Department of Health and Human Resources, Bethesda
    • Hainline, A., Karon, J. & Lippel, K., eds (1982) Lipid Research Clinics Program: Lipid and Lipoprotein Analysis, 2nd edn. US Department of Health and Human Resources, Bethesda.
    • (1982) Lipid Research Clinics Program: Lipid and Lipoprotein Analysis
  • 32
    • 0031732361 scopus 로고    scopus 로고
    • Phenotype and genetic analysis of a syndrome caused by an inactivating mutation in the growth hormone-releasing hormone receptor: Dwarfism of Sindh
    • Maheshwari, H.G., Silverman, B.L., Dupuis, J. & Baumann, G. (1998) Phenotype and genetic analysis of a syndrome caused by an inactivating mutation in the growth hormone-releasing hormone receptor: dwarfism of Sindh. Journal of Clinical Endocrinology and Metabolism, 83, 4065-4074.
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , pp. 4065-4074
    • Maheshwari, H.G.1    Silverman, B.L.2    Dupuis, J.3    Baumann, G.4
  • 34
    • 0034974980 scopus 로고    scopus 로고
    • Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: Evidence for a role for non-GHRH inputs into the generation of GH pulses
    • Roelfsema, F., Biermasz, N.R., Veldman, R.G., Veldhuis, J.D., Frolich, M., Stokvis-Brantsma, W.H. & Wit, J.M. (2001) Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses. Journal of Clinical Endocrinology and Metabolism, 86, 2459-2464.
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , pp. 2459-2464
    • Roelfsema, F.1    Biermasz, N.R.2    Veldman, R.G.3    Veldhuis, J.D.4    Frolich, M.5    Stokvis-Brantsma, W.H.6    Wit, J.M.7
  • 35
    • 0036081099 scopus 로고    scopus 로고
    • Maheshwari, H.G., Pezzoli, S.S., Rahim, A., Shalet, S.M., Thorner, M.O. & Baumann, G. (2002) Pulsatile growth hormone secretion persists in genetic growth hormone-releasing hormone resistance. American Journal of Physiology. Endocrinology and Metabolism, 282, 4, E943-4, E951.
    • Maheshwari, H.G., Pezzoli, S.S., Rahim, A., Shalet, S.M., Thorner, M.O. & Baumann, G. (2002) Pulsatile growth hormone secretion persists in genetic growth hormone-releasing hormone resistance. American Journal of Physiology. Endocrinology and Metabolism, 282, 4, E943-4, E951.
  • 36
    • 0036979609 scopus 로고    scopus 로고
    • Van Der Sluis, I.M., Boot, A.M., Hop, W.C., De Rijke, Y.B., Krenning, E.P. & De Muinck Keizer-Schrama, S.M. (2002) Long-term effects of growth hormone therapy on bone mineral density, body composition, and serum lipid levels in growth hormone deficient children: a 6-year follow-up study. Hormone Research, 58, 207-214.
    • Van Der Sluis, I.M., Boot, A.M., Hop, W.C., De Rijke, Y.B., Krenning, E.P. & De Muinck Keizer-Schrama, S.M. (2002) Long-term effects of growth hormone therapy on bone mineral density, body composition, and serum lipid levels in growth hormone deficient children: a 6-year follow-up study. Hormone Research, 58, 207-214.
  • 37
    • 0028274615 scopus 로고
    • Magnetic resonance imaging evaluation of adipose tissue and muscle tissue mass in children with growth hormone (GH) deficiency, Turner's syndrome, and intrauterine growth retardation during the first year of treatment with GH
    • Leger, J., Carel, C., Legrand, I., Paulsen, A., Hassan, M. & Czernichow, P. (1994) Magnetic resonance imaging evaluation of adipose tissue and muscle tissue mass in children with growth hormone (GH) deficiency, Turner's syndrome, and intrauterine growth retardation during the first year of treatment with GH. Journal of Clinical Endocrinology and Metabolism, 78, 904-909.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.78 , pp. 904-909
    • Leger, J.1    Carel, C.2    Legrand, I.3    Paulsen, A.4    Hassan, M.5    Czernichow, P.6
  • 38
    • 0036065154 scopus 로고    scopus 로고
    • Changes in adiposity and excess body weight correlate with growth responses but not with decreases in low-density lipoprotein cholesterol levels during GH treatment in GH-deficient children
    • Kuromaru, R., Kohno, H. & Hara, T. (2002) Changes in adiposity and excess body weight correlate with growth responses but not with decreases in low-density lipoprotein cholesterol levels during GH treatment in GH-deficient children. Clinical Endocrinology, 56, 799-803.
    • (2002) Clinical Endocrinology , vol.56 , pp. 799-803
    • Kuromaru, R.1    Kohno, H.2    Hara, T.3
  • 39
    • 0033756754 scopus 로고    scopus 로고
    • Body composition, blood pressure, and lipid metabolism before and during longterm growth hormone (GH) treatment in children with short stature born small for gestational age either with or without GH deficiency
    • Sas, T., Mulder, P. & Hokken-Koelega, A. (2000) Body composition, blood pressure, and lipid metabolism before and during longterm growth hormone (GH) treatment in children with short stature born small for gestational age either with or without GH deficiency. Journal of Clinical Endocrinology and Metabolism, 85, 3786-3792.
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , pp. 3786-3792
    • Sas, T.1    Mulder, P.2    Hokken-Koelega, A.3
  • 40
    • 0035339669 scopus 로고    scopus 로고
    • Alterations in body composition and fat distribution in growth hormone-deficient prepubertal children during growth hormone therapy
    • Roemmich, J.N., Huerta, M.G., Sundaresan, S.M. & Rogol, A.D. (2001) Alterations in body composition and fat distribution in growth hormone-deficient prepubertal children during growth hormone therapy. Metabolism, 50, 537-547.
    • (2001) Metabolism , vol.50 , pp. 537-547
    • Roemmich, J.N.1    Huerta, M.G.2    Sundaresan, S.M.3    Rogol, A.D.4
  • 42
    • 0034685191 scopus 로고    scopus 로고
    • Incidence of diabetes mellitus and impaired glucose tolerance in children and adolescents receiving growth-hormone treatment
    • Cutfield, W.S., Wilton, P., Bennmarker, H., Albertsson-Wikland, K., Chatelain, P., Ranke, M.B. & Price, D.A. (2000) Incidence of diabetes mellitus and impaired glucose tolerance in children and adolescents receiving growth-hormone treatment. Lancet, 355, 610-613.
    • (2000) Lancet , vol.355 , pp. 610-613
    • Cutfield, W.S.1    Wilton, P.2    Bennmarker, H.3    Albertsson-Wikland, K.4    Chatelain, P.5    Ranke, M.B.6    Price, D.A.7
  • 43
    • 0034492173 scopus 로고    scopus 로고
    • Safety issues in children and adolescents during growth hormone therapy - a review
    • Clayton, P.E. & Cowell, C.T. (2000) Safety issues in children and adolescents during growth hormone therapy - a review. Growth Hormone and IGF Research, 10, 306-317.
    • (2000) Growth Hormone and IGF Research , vol.10 , pp. 306-317
    • Clayton, P.E.1    Cowell, C.T.2
  • 44
    • 0029994322 scopus 로고    scopus 로고
    • Carbohydrate metabolism in children receiving growth hormone for 5 years. Chronic renal insufficiency compared with growth hormone deficiency, Turner syndrome, and idiopathic short stature. Genentech Collaborative Group
    • Saenger, P., Attie, K.M., Dimartino-Nardi, J. & Fine, R.N. (1996) Carbohydrate metabolism in children receiving growth hormone for 5 years. Chronic renal insufficiency compared with growth hormone deficiency, Turner syndrome, and idiopathic short stature. Genentech Collaborative Group. Pediatric Nephrology, 10, 261-263.
    • (1996) Pediatric Nephrology , vol.10 , pp. 261-263
    • Saenger, P.1    Attie, K.M.2    Dimartino-Nardi, J.3    Fine, R.N.4
  • 45


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.