Simultaneous evaluation of myocardial blood flow, cardiac function and lung water content using [15O]H2O and positron emission tomography

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 34, Issue 4, 2007, Pages 563-572

  Naum, Alexandru ^a   Tuunanen, Helena ^a   Engblom, Erik ^a   Oikonen, Vesa ^a   Sipilä, Hannu ^a   Iozzo, Patricia ^a,b   Nuutila, Pirjo ^a   Knuuti, Juhani ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

Author keywords

Cardiac output; Lung water content; MBF; PET; Principal component analysis

Indexed keywords

WATER O 15;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL INDICATOR; COMPARATIVE STUDY; CONGESTIVE CARDIOMYOPATHY; CONTROL GROUP; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; DILUTION; ECHOCARDIOGRAPHY; FEMALE; HEART FUNCTION; HEART MUSCLE BLOOD FLOW; HEART MUSCLE PERFUSION; HEART OUTPUT; HEART RIGHT VENTRICLE; HEART STROKE VOLUME; HEART VENTRICLE SEPTUM; HEART VENTRICLE WALL; HUMAN; INTERMETHOD COMPARISON; LUNG EDEMA; LUNG FLUID; MALE; MEDICAL ASSESSMENT; POSITRON EMISSION TOMOGRAPHY; REGRESSION ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; VOLUNTEER;

BODY WATER; CARDIOMYOPATHY, DILATED; CORONARY CIRCULATION; FEASIBILITY STUDIES; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LUNG; MALE; MIDDLE AGED; OXYGEN RADIOISOTOPES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; WATER;

EID: 33947236058     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-006-0259-3     Document Type: Article

References (20)

1. Kaufmann PA, Camici PG. Myocardial blood flow measurement by PET: technical aspects and clinical applications. J Nucl Med 2005;46(1):75-88.
2. Rimoldi OE, Camici PG. Positron emission tomography for quantitation of myocardial perfusion. J Nucl Cardiol 2004;11(4):482-90.
3. Stolen KQ, Kemppainen J, Kalliokoski KK, Hallsten K, Luotolahti M, Karanko H, et al. Myocardial perfusion reserve and peripheral endothelial function in patients with idiopathic dilated cardiomyopathy. Am J Cardiol 2004;93(1):64-8. Jan.
4. Kalliokoski KK, Nuutila P, Laine H, Luotolahti M, Janatuinen T, Raitakari OT, et al. Myocardial perfusion and perfusion reserve in endurance-trained men. Med Sci Sports Exerc 2002;34(6):948-53.
5. Ahn JY, Lee DS, Lee JS, Kim SK, Cheon GJ, Yeo JS, et al. Quantification of regional myocardial blood flow using dynamic H2(15)O PET and factor analysis. J Nucl Med 2001;42(5):782-7.
6. Lee JS, Lee DS, Ahn JY, Cheon GJ, Kim SK, Yeo JS, et al. Blind separation of cardiac components and extraction of input function from H(2)(15)O dynamic myocardial PET using independent component analysis. J Nucl Med 2001;42(6):938-43.
7. Hermansen F, Ashburner J, Spinks TJ, Kooner JS, Camici PG, Lammertsma AA. Generation of myocardial factor images directly from the dynamic oxygen-15-water scan without use of an oxygen-15-carbon monoxide blood-pool scan. J Nucl Med 1998;39:1696-702.
8. Lange NR, Schuster DP. The measurement of lung water. Crit Care 1999;3(2):R19-24.
9. Loening AM, Gambhir SS. AMIDE: a free software tool for multimodality medical image analysis. Mol Imaging 2003;2(3):131-7.
10. Schuster DP, Mintun MA, Green MA, Ter-Pogossian MM. Regional lung water and hematocrit determined by positron emission tomography. J Appl Physiol 1985;59:860-8.
11. Velazquez M, Haller J, Amundsen T, Schuster DP. Regional lung water measurements with PET: accuracy, reproducibility, and linearity. J Nucl Med 1991;32:719-25.
12. Iida H, Rhodes C, de Silva R, Araujo LI, Bloomfield PM, Lammertsma AA, et al. Use of the left ventricular time-activity curve as a noninvasive input function in dynamic oxygen-15-water positron emission tomography. J Nucl Med 1992;33:1669-77.
13. 15O and dynamic positron-emission tomography: strategy for quantification in relation to the partial-volume effect. Circulation 1988;78:104-15.
14. Chen EQ, MacIntyre WJ, Fouad FM, Brunken RC, Go RT, Wong CO, et al. Measurement of cardiac output with first-pass determination during rubidium-82 PET myocardial perfusion imaging. Eur J Nucl Med 1996;23:993-6.
15. Hove JD, Kofoed KF, Wu HM, Holm S, Friberg L, Meyer C, et al. Simultaneous cardiac output and regional myocardial perfusion determination with PET and nitrogen 13 ammonia. J Nucl Cardiol 2003;10(1):28-33.
16. Sorensen J, Stahle E, Langstrom B, Frostfeldt G, Wikstrom G, Hedenstierna G. Simple and accurate assessment of forward cardiac output by use of 1-(11)C-acetate PET verified in a pig model. J Nucl Med 2003;44(7):1176-83.
17. Frostfeldt G, Sorensen J, Lindahl B, Valind S, Wallentin L. Development of myocardial microcirculation and metabolism in acute ST-elevation myocardial infarction evaluated with positron emission tomography. J Nucl Cardiol 2005;12(1):43-54.
18. Passing H, Bablok W. A new biometrical procedure for testing the equality of measurements from two different analytical methods. Application of linear regression procedures for method comparison studies in clinical chemistry, part i. J Clin Chem Clin Biochem 1983;21:709-20.
19. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1(8476):307-10.
20. Chareonthaitawee P, Kaufmann PA, Rimoldi O, Camici PG. Heterogeneity of resting and hyperemic myocardial blood flow in healthy humans. Cardiovasc Res 2001;50(1):151-61.