Brine shrimp toxicity evaluation of some Tanzanian plants used traditionally for the treatment of fungal infections

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 4, Issue 2, 2007, Pages 219-225

  Moshi, Mainen J ^a   van den Beukel, Carolien J P ^b   Hamza, Omar J M ^a   Mbwambo, Zakaria H ^a   Nondo, Ramadhani O S ^a   Masimba, Pax J ^a   Matee, Mecky I N ^a   Kapingu, Modest C ^a   Mikx, Frans ^b   Verweij, Paul E ^b   van der Ven, André J A M ^b  

^a MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Brine shrimp test; Toxicity evaluation; Traditional antifungal plants

Indexed keywords

ACACIA NILOTICA EXTRACT; ACACIA ROBUSTA EXTRACT; ACALYPHA FRUTICOSA EXTRACT; AGAURIA SALICIFOLIA EXTRACT; ALOE LATERITIA EXTRACT; ANNONA SENEGALENSIS EXTRACT; BALANITES AEGYPTIACA EXTRACT; CASSIA ABBREVIATA EXTRACT; CASSIA SINGUENA EXTRACT; CHYRSOPHYLLUM BANGWEOLENSE EXTRACT; CISSUS PETIOLATA EXTRACT; CLAUSENA ANISATA EXTRACT; COMMIPHORA PTELEIFOLIA EXTRACT; CORDIA AFRICANA EXTRACT; CORONOPUS DIDYMUS EXTRACT; CROTON SCHEFFLERI EXTRACT; CUCUMIS ACULEATUS EXTRACT; CYPHOSTEMMA HILDEBRANDTII EXTRACT; DIOSPYROS USAMBARENSIS EXTRACT; DRYMARIA CORDATA EXTRACT; ELAEODENDRON BUNCHANANII EXTRACT; ELAEODENDRON SCHLECHTERANUM EXTRACT; ERYTHRINA ABYSSINICA EXTRACT; EUPHORBIA HETERPHYLLA EXTRACT; HERBACEOUS AGENT; HYMENODACTYON PARVIFOLIUM EXTRACT; KIGELIA AFRICANA EXTRACT; OCIMUM SUAVE EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACACIA; ACACIA NILOTICA; ACACIA ROBUSTA; ACALYPHA FRUTICOSA; AGAURIA SALICIFOLIA; ALOE; ALOE LATERITIA; ANNONA SENEGALENSIS; ANNONACEAE; ARTEMIA; ARTICLE; BALANITES; BALANITES AEGYPTIACA; BASIL; BIGNONIACEAE; BORAGINACEAE; CAESALPINIA; CARYOPHYLLACEAE; CASSIA ABBREVIATA; CASSIA SINGUENA; CELASTRACEAE; CHYRSOPHYLLUM BANGWEOLENSE; CISSUS PETIOLATA; CLAUSENA ANISATA; COMMIPHORA PTELEIFOLIA; CONTROLLED STUDY; CORDIA AFRICANA; CORONOPUS DIDYMUS; CROTON SCHEFFLERI; CRUCIFERA; CUCUMBER; CUCUMIS ACULEATUS; CYPHOSTEMMA HILDEBRANDTII; DIOSPYROS USAMBARENSIS; DRYMARIA CORDATA; EBENACEAE; ELAEODENDRON BUNCHANANII; ELAEODENDRON SCHLECHTERANUM; ERICACEAE; ERYTHRINA ABYSSINICA; EUPHORBIA; EUPHORBIA HETERPHYLLA; HYMENODACTYON PARVIFOLIUM; KIGELIA AFRICANA; LC 50; LEGUME; LETHALITY; MYCOSIS; NONHUMAN; RUBIACEAE; RUTACEAE; SAPOTACEAE; SPECIES DIFFERENCE; TANZANIA; TOXICITY TESTING; TRADITIONAL MEDICINE; VITACEAE;

EID: 33947235734     PISSN: 01896016     EISSN: 01896016     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. AIDS Analysis Africa, February 1996, pp 12-13.
2. Bastert J, Schaller M, Korting HC, Evans EG (2001). Current and future approaches to antimycotic treatment in the era of resistant fungi and immunocompromised hosts. Intl J Antimicr Agents 17: 81-91.
3. Debruyne D (1997). Clinical pharmacokinetics of fluconazole in superficial and systemic mycoses. Clin Pharmacok 33:52-77.
4. Hamza OJM, van den Beukel CJP, Mecky I.N. Matee MIN, Moshi MJ, Mikx F, Haji O. Selemani HO, Mbwambo ZH, Van der Ven AJAM, Verweij PE (2006). Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections. J Ethnopharmacol. May 22; [Epub ahead of print] PMID: 16829001.
5. Kilima PM, Ostermayer I, Shija M, Wolff M.M, Evans PJ (1993). Drug utilization, prescribing habits and patients in City Council Health Facilities, Dar es Salaam, Tanzania. DUHP, Swiss Tropical Institute, Basel, p. 19.
6. Levin Y, Sherer Y, Bibi H, Schlesinger M, Hay E (2000). Rare Jatropha multifida intoxication in two children. J Emerg Med 19:173-175.
7. Litchfield Jr JR, Wilcoxon F (1949). A simplified method of evaluating dose-effect experiments. J Pharmacol Exper Therap 96: 99-13.
8. Meyer BN, Ferrigini RN, Jacobsen LB, Nicholas DE, Mc Laughlin JL (1982). Brine shrimp: a convenient general bioassay for active plant constituents. Planta Med 45:31-35.
9. Powerly WG (1992). Mucosal candidiasis caused by non-albicans species of Candida in HIV-positive patients. AIDS 6:604-605.
10. Redding S, Smith J, Farinacci G., Rinaldi M, Fothergill A, Rhine-Chalberg J, Pfaller M (1994). Resistance of Candida albicans to fluconazole during treatment of oropharyngeal candidiasis in a patient with AIDS: documentation by in vitro susceptibility testing and DNA subtype analysis. Clin Infect Dis 18:240-242.
11. Rocha e Silva M (1943). Studies on poisonous plants in the state of Sao Paulo: toxicological expts. on 27 plants which have been suspected of toxicity. Arq Instit Biol (Sao Paulo) 14:15.
12. Ruhnke M, Eigler A, Tennagen I, Geiseler B, Engelmann E, Trautmann M (1994). Emergence of fluconazole-resistant strains of Candida albicans in patients with reccurent oro-pharyngeal candidosis and human immunodefficiency virus infection. J Clin Microbiol 32:2092-2098.
13. Sangeorzan JA, Bradley SF, He X, Zarins LT, Ridenour GL, Tiballi RN, Kauffman CA (1994). Epidemiology of oral candidiasis in HIV infected patients: Colonization, infection, treatment, and emergence of fluconazole resistance. Am J Med 97:339-346.
14. UNAIDS (2004). Report on the global AIDS epidemic. 2004