Not yet time to use mortality as an outcome in trials of intravenous fluid therapy in severe malaria

Trends in Parasitology

Volumn 23, Issue 4, 2007, Pages 138-139

  Planche, Tim ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GELATIN SUCCINATE; GLUCOSE; INFUSION FLUID; PHENOBARBITAL; SODIUM CHLORIDE;

ADJUVANT THERAPY; BACTERIAL INFECTION; DEPLETION; DISEASE SEVERITY; FLUID THERAPY; HUMAN; LACTIC ACIDOSIS; LETTER; MALARIA; MEDICAL LITERATURE; MORTALITY; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; RANDOMIZATION; RISK ASSESSMENT;

CHILD; FLUID THERAPY; HUMANS; INFUSIONS, INTRAVENOUS; MALARIA; TREATMENT OUTCOME;

EID: 33947222042     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2007.01.010     Document Type: Letter

References (15)

1. Maitland K. Severe malaria: lessons learned from the management of critical illness in children. Trends Parasitol. 22 (2006) 457-462
2. Maitland K., and Newton C.R. Acidosis of severe falciparum malaria: heading for a shock?. Trends Parasitol. 21 (2005) 11-16
3. Planche T. Malaria and fluids - balancing acts. Trends Parasitol. 21 (2005) 562-567
4. Planche T., et al. Assessment of volume depletion in children with malaria. PLoS Med. 1 (2004) e18
5. Akech S., et al. Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial. PLoS Clin. Trials 1 (2006) e21
6. Maitland K., et al. Response to volume resuscitation in children with severe malaria. Pediatr. Crit. Care Med. 4 (2003) 426-431
7. Crawley J., et al. Effect of phenobarbital on seizure frequency and mortality in childhood cerebral malaria: a randomised, controlled intervention study. Lancet 355 (2000) 701-706
8. Woodrow C., and Planche T. Inadequate evidence to support phase III studies of albumin in severe malaria. PLoS Clin. Trials 1 (2006) e21. http://clinicaltrials.plosjournals.org/perlserv/%3Frequest=read-response%26doi=10.1371/journal.pctr.0010021%23r0011317 http://clinicaltrials.plosjournals.org/perlserv/?request=read-response&doi=10.1371/journal.pctr.0010021#r0011317
9. Clark I.A., et al. Human malarial disease: a consequence of inflammatory cytokine release. Malar. J. 5 (2006) 85
10. Awandare G.A., et al. Increased levels of inflammatory mediators in children with severe Plasmodium falciparum malaria with respiratory distress. J. Infect. Dis. 194 (2006) 1438-1446
11. Planche T., and Krishna S. Severe malaria: metabolic complications. Curr. Mol. Med. 6 (2006) 141-153
12. Maitland K., et al. Randomized trial of volume expansion with albumin or saline in children with severe malaria: preliminary evidence of albumin benefit. Clin. Infect. Dis. 40 (2005) 538-545
13. Maitland K., et al. Pre-transfusion management of children with severe malarial anaemia: a randomised controlled trial of intravascular volume expansion. Br. J. Haematol. 128 (2005) 393-400
14. Rivers E., et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N. Engl. J. Med. 345 (2001) 1368-1377
15. Day N. Fluid resuscitation in malaria: the need for new randomised clinical trials. PLoS Clin. Trials 1 (2006) e24