Differentiation of human keratinocytes requires the vitamin D receptor and its coactivators

Journal of Investigative Dermatology

Volumn 127, Issue 4, 2007, Pages 748-750

  Bollag, Wendy B ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CALCITRIOL; HISTONE ACETYLTRANSFERASE; MESSENGER RNA; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; SHORT HAIRPIN RNA; VITAMIN D RECEPTOR;

CALCIUM METABOLISM; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CLINICAL RESEARCH; DIMERIZATION; DISEASE MARKER; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; EPIDERMIS; GENE OVEREXPRESSION; GENETIC MANIPULATION; HORMONAL REGULATION; HYPERCALCEMIA; KERATINOCYTE; KNOCKOUT MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; REVIEW; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

CELL DIFFERENTIATION; HUMANS; KERATINOCYTES; RECEPTORS, CALCITRIOL;

EID: 33947220467     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700692     Document Type: Note

References (10)

1. Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Choi EH et al. (2004) 25-Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis. J Invest Dermatol 122:984-92
2. Bikle DD, Oda Y, Xie Z (2005) Vitamin D and skin cancer: a problem in gene regulation. J Steroid Biochem Mol Biol 97:83-91
3. Eelen G, Verlinden L, De Clercq P, Vandewalle M, Bouillon R, Verstuyf A (2006) Vitamin D analogs and coactivators. Anticancer Res 26:2717-21
4. Fogh K, Kragballe K (2004) New vitamin D analogs in psoriasis. Curr Drug Targets Inflamm Allergy 3:199-204
5. Hanley K, Komuves LG, Ng DC, Schoonjans K, He SS, Lau P et al. (2000) Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. J Biol Chem 275:11484-91
6. Hawker NP, Pennypacker SD, Chang SM, Bikle DD (2007) Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3. J Invest Dermatol 127:874-880
7. Lonard DM, O'Malley BW (2006) The expanding cosmos of nuclear receptor coactivators. Cell 125:411-4
8. Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang C-PB et al. (2004) Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in VDR transactivation during keratinocyte differentiation. J Steroid Biochem Mol Biol 89-90:273-6
9. Saitou M, Sugai S, Tanaka T, Shimouchi K, Fuchs E, Narumiya S et al. (1995) Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor. Nature 374:118-9
10. Tang Q-Q, Otto TC, Lane MD (2003) Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc Natl Acad Sci USA 100:44-9