Composite splenic marginal zone lymphoma and mantle cell lymphoma arising from 2 independent B-cell clones

Human Pathology

Volumn 38, Issue 4, 2007, Pages 660-667

  Lefebvre, Christine ^a,b,c   Fabre, Blandine ^a,b,d   Vettier, Claire ^a,b,c   Rabin, Laetitia ^a,b   Florin, Anne ^a,b   Wang, Jin ^d   Gressin, Rémy ^a,b,d   Jacob, Marie Christine ^a,b,e   Callanan, Mary ^a,b,c   Leroux, Dominique ^a,b,c  

^a INSERM   (France)

^b UNIV GRENOBLE ALPES   (France)

^c HÔPITAL MICHALLON   (France)

^d GRENOBLE UNIVERSITY HOSPITAL   (France)

^e ETABLISSEMENT FRANÇAIS DU SANG   (France)

Author keywords

Composite lymphoma; Cyclin D1; FISH; Mantle cell lymphoma; NFKB2; Splenic marginal zone lymphoma; t(10; 14)(q24; q32); t(11; 14)(q13; q32)

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN;

AGED; ARTICLE; B LYMPHOCYTE; CASE REPORT; FLUORESCENCE IN SITU HYBRIDIZATION; GENE REARRANGEMENT; GENE SEQUENCE; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LYMPHOCYTE SUBPOPULATION; MALE; MALIGNANT TRANSFORMATION; MANTLE CELL LYMPHOMA; MOLECULAR CLONING; SPLEEN TUMOR; SPLENIC MARGINAL ZONE LYMPHOMA;

AGED; CYCLINS; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOMA, B-CELL; LYMPHOMA, LOW-GRADE; LYMPHOMA, MANTLE-CELL; MALE; NEOPLASMS, MULTIPLE PRIMARY; NF-KAPPA B P52 SUBUNIT; SPLENIC NEOPLASMS;

EID: 33947216027     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.08.023     Document Type: Article

References (27)

1. Kim H. Composite lymphoma and related disorders. Am J Clin Pathol 99 (1993) 445-451
2. Brauninger A., Hansmann M.L., Strickler J.G., et al. Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's lymphoma. N Engl J Med 340 (1999) 1239-1247
3. Volk A.L., Vannucci S.A., Cook W., Thompson K.A., and Listinsky C.M. Composite mycosis fungoides and B-cell chronic lymphocytic leukemia. Ann Diagn Pathol 6 (2002) 172-182
4. Fend F., Quintanilla-Martinez L., Kumar S., et al. Composite low grade B-cell lymphomas with two immunophenotypically distinct cell populations are true biclonal lymphomas. A molecular analysis using laser capture microdissection. Am J Pathol 154 (1999) 1857-1866
5. Tsang P., Pan L., Cesarman E., Tepler J., and Knowles D.M. A distinctive composite lymphoma consisting of clonally related mantle cell lymphoma and follicle center cell lymphoma. Hum Pathol 30 (1999) 988-992
6. Zamo A., Zanotti R., Lestani M., et al. Molecular characterization of composite mantle cell and follicular lymphoma. Virchows Arch 448 (2006) 639-644
7. Tinguely M., Rosenquist R., Sundstrom C., et al. Analysis of a clonally related mantle cell and Hodgkin lymphoma indicates Epstein-Barr virus infection of a Hodgkin/Reed-Sternberg cell precursor in a germinal center. Am J Surg Pathol 27 (2003) 1483-1488
8. Caleo A., Sanchez-Aguilera A., Rodriguez S., et al. Composite Hodgkin lymphoma and mantle cell lymphoma: two clonally unrelated tumors. Am J Surg Pathol 27 (2003) 1577-1580
9. Hayes S.J., Banerjee S.S., Cook Y., Houghton J.B., and Menasce L.P. Composite mantle-cell lymphoma and classical Hodgkin lymphoma. Histopathology 48 (2006) 621-623
10. Cachia A.R., Diss T.C., and Isaacson P.G. Composite mantle-cell lymphoma and plasmacytoma. Hum Pathol 28 (1997) 1291-1295
11. Rosenquist R., Roos G., Erlanson M., Kuppers R., Brauninger A., and Hansmann M.L. Clonally related splenic marginal zone lymphoma and Hodgkin lymphoma with unmutated V gene rearrangements and a 15-yr time gap between diagnoses. Eur J Haematol 73 (2004) 210-214
12. Wang S.A., Olson N., Zukerberg L., and Harris N.L. Splenic marginal zone lymphoma with micronodular T-cell rich B-cell lymphoma. Am J Surg Pathol 30 (2006) 128-132
13. Heintel D., Streubel B., Welzel N., et al. Burkitt lymphoma following splenic marginal zone lymphoma. Evidence for two independent B-cell clones. Cancer Genet Cytogenet 141 (2003) 86-88
14. Baseggio L., Gazzo S., Callet-Bauchu E., et al. An unusual case of indolent B-cell lymphoma with distinct chronic lymphocytic leukemia and marginal zone differentiation according to the site of involvement. Leuk Lymphoma 46 (2005) 1369-1374
15. Lima M., Goncalves C., Marques L., et al. Association of CD4+/CD56+/CD57+/CD8+(dim) large granular lymphocytic leukemia, splenic B-cell lymphoma with circulating villous lymphocytes, and idiopathic erythrocytosis. Ann Hematol 80 (2001) 685-690
16. Papadaki T., Stamatopoulos K., Kosmas C., Kapsimali V., and Economopoulos T. A unique case of splenic marginal zone-cell lymphoma with synchronous clonal T-cell large granular lymphocyte proliferation: an immunologic, immunohistochemical and genotypic study. Leuk Res 27 (2003) 85-87
17. van Dongen J.J., Langerak A.W., Bruggemann M., et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 17 (2003) 2257-2317
18. Angelopoulou M.K., Siakantariz M.P., Vassilakopoulos T.P., et al. The splenic form of mantle cell lymphoma. Eur J Haematol 68 (2002) 12-21
19. Sole F., Salido M., Espinet B., et al. Splenic marginal zone B-cell lymphomas: two cytogenetic subtypes, one with gain of 3q and the other with loss of 7q. Haematologica 86 (2001) 71-77
20. Beinke S., and Ley S.C. Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology. Biochem J 382 (2004) 393-409
21. Ruiz-Ballesteros E., Mollejo M., Rodriguez A., et al. Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis. Blood 106 (2005) 1831-1838
22. Algara P., Mateo M.S., Sanchez-Beato M., et al. Analysis of the IgV(H) somatic mutations in splenic marginal zone lymphoma defines a group of unmutated cases with frequent 7q deletion and adverse clinical course. Blood 99 (2002) 1299-1304
23. Traverse-Glehen A., Davi F., Ben Simon E., et al. Analysis of VH genes in marginal zone lymphoma reveals marked heterogeneity between splenic and nodal tumors and suggests the existence of clonal selection. Haematologica 90 (2005) 470-478
24. Camacho F.I., Algara P., Rodriguez A., et al. Molecular heterogeneity in MCL defined by the use of specific VH genes and the frequency of somatic mutations. Blood 101 (2003) 4042-4046
25. Orchard J., Garand R., Davis Z., et al. A subset of t(11;14) lymphoma with mantle cell features displays mutated IgVH genes and includes patients with good prognosis, nonnodal disease. Blood 101 (2003) 4975-4981
26. de Jong D. Molecular pathogenesis of follicular lymphoma: a cross talk of genetic and immunologic factors. J Clin Oncol 23 (2005) 6358-6363
27. Rodig S., Healey B., Pinkus G., Kuo F., Dal Cin P., and Kutok J. Mantle cell lymphoma arising within primary nodal marginal zone lymphoma; a unique presentation of two uncommon B-cell lymphoproliferative disorders. Cancer Genet Cytogenet 171 (2006) 44-51