Protection or reconstruction: Neuroprotective effects on transforming growth factor-β1 at the cost of reduced neurogenesis;Schutz oder Neuaufbau: Neuroprotektive Effekte des Transforming Growth Faktors-β1, auf Kosten einer reduzierten Neurogenese?

Neuroforum

Volumn 13, Issue 1, 2007, Pages 4-12

  Aigner, Ludwig ^a   Winkler, Jürgen ^a   Bogdahn, Ulrich ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

CNS repair; Cytokines; Neural stem cells; Neurodegenerative diseases; Neurogenesis

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1;

AGING; ALZHEIMER DISEASE; ARTICLE; CELL MIGRATION; CELL MOTION; CELL REGENERATION; CYTOSTASIS; DEGENERATIVE DISEASE; DOWN REGULATION; HUMAN; IMMUNE RESPONSE; IMMUNOREGULATION; MITOSIS INHIBITION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PLEIOTROPY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 33947204209     PISSN: 09470875     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Bottner, M., Krieglstein, K. and Unsicker, K. (2000): The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions. J Neurochem 75: 2227-2240.
2. Krieglstein, K., Strelau, J., Schober, A., Sullivan, A. und Unsicker, K. (2002): TGF-beta and the regulation of neuron survival and death, J Physiol Paris 96: 25-30.
3. Unsicker, K. und Krieglstein, K. (2002): TGF-betas and their roles in the regulation of neuron survival. Adv Exp Med Biol 513: 353-374.
4. Wachs, F.P., Winner, B., Couillard-Despres, S., Schiller, T., Aigner, R., Winkler, J., Bogdahn, U. und Aigner, L. (2006): Transforming growth factor-betal is a negative modulator of adult neurogenesis. J Neuropathol Exp Neurol 65:358-370.
5. Wyss-Coray, T. und Mucke, L. (2002): Inflammation in neurodegenerative disease - a double-edged sword. Neuron 35: 419-432.