Mitigation of radiation-induced optic neuropathy in rats by ACE inhibitor ramipril: Importance of ramipril dose and treatment time

Journal of Neuro-Oncology

Volumn 82, Issue 2, 2007, Pages 119-124

  Ryu, Samuel ^a   Kolozsvary, Andrew ^a   Jenrow, Kenneth A ^a   Brown, Stephen L ^a   Kim, Jae Ho ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

ACE inhibitor; Radiation induced optic neuropathy; Radioprotection; Radiosurgery; Ramipril

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DRINKING WATER; LOSARTAN; RAMIPRIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONOTHERAPY; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; EVOKED VISUAL RESPONSE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OPTIC NERVE DISEASE; PATHOLOGICAL ANATOMY; RADIATION INJURY; RADIATION PROTECTION; RADIOSURGERY; RAT; TREATMENT OUTCOME;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, RADIATION; EVOKED POTENTIALS, VISUAL; INJECTIONS, INTRAPERITONEAL; MALE; OPTIC NERVE; OPTIC NERVE DISEASES; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RAMIPRIL; RATS; RATS, INBRED F344; SURVIVAL RATE; TIME FACTORS;

EID: 33947194301     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-006-9256-4     Document Type: Article

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