Cyclooxygenase-2 expression in advanced nasopharyngeal carcinoma-a prognostic evaluation and correlation with hypoxia inducible factor 1α and vascular endothelial growth factor

Oral Oncology

Volumn 43, Issue 4, 2007, Pages 373-378

  Chan, Charles M L ^a   Ma, Brigette B Y ^a   Hui, Edwin P ^a   Wong, Sze C C ^a   Mo, Frankie K F ^a   Leung, Sing F ^a   Kam, Michael K M ^a   Chan, Anthony T C ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Cyclooxygenase 2; Hypoxia inducible factor 1 ; Nasopharyngeal carcinoma; Vascular endothelial growth factor

Indexed keywords

CISPLATIN; CYCLOOXYGENASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LATENT MEMBRANE PROTEIN 1; VASCULOTROPIN;

ADVANCED CANCER; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; EPSTEIN BARR VIRUS; FEMALE; HUMAN; HUMAN TISSUE; LOW DRUG DOSE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; TUMOR BIOPSY;

ADULT; AGED; BIOPSY; COHORT STUDIES; CYCLOOXYGENASE 2; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; PROGNOSIS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33947194211     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2006.04.004     Document Type: Article

References (28)

1. Schmedtje J.F., Liu W.L., DuBois R.N., and Runge M.S. Hypoxia induces cyclooxygenase-2 via the NF-B p65 transcription factor in human vascular endothelial cells. J Biol Chem 272 (1997) 601-608
2. Zha S., Yegnasubramanian V., Nelson W.G., Isaacs W.B., and De Marzo A.M. Cyclooxygenases in cancer: progress and perspective. Cancer Lett 215 (2004) 1-20
3. Liu X.H., Kirschenbaum A., Lu M., Yao S., Dosoretz A., Holland J.F., et al. Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. J Biol Chem 277 (2002) 500081-500086
4. Wang W., Bergh A., and Damber J.E. Cyclooxygenase-2 expression correlates with local chronic inflammation and tumor neovascularization in human prostate cancer. Clin Cancer Res 11 (2005) 350-356
5. O'Byrne K.J., and Dalgleish A. Chronic immune activation and inflammation as the cause of malignancy. Br J Cancer 85 (2001) 473-483
6. Huang S.P., Shun C.T., Wang H.P., Hsieh C.Y., Kuo M.L., and Lin J.T. Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma. J Biomed Sci 12 (2005) 229-241
7. Tan K.B., and Putti T. Cyclooxygenase 2 expression in nasopharyngeal carcinoma: immunohistochemical findings and potential implications. J Clin Pathol 58 (2005) 535-538
8. Murono S., Inoue H., Tanabe T., Joab I., Yoshizaki T., Furukawa M., et al. Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells. Proc Natl Acad Sci USA 98 (2001) 6905-6910
9. Yoshizaki T., Murono S., Furukawa M., Pagano J., Wakisaka N., Kondo S., et al. Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha. Mol Cell Biol 24 (2004) 5223-5234
10. Wakisaka N., and Pagano J. Epstein-Barr virus induces invasion and metastasis factors. Anticancer Res 23 (2003) 2133-2138
11. Jones A., Fujiyama C., Blanche C., Moore J.W., Fuggle S., Cranston D., et al. Relation of vascular endothelial growth factor production to expression and regulation of hypoxia-inducible factor-1 and hypoxia-inducible factor-2 in human bladder tumors and cell lines. Clin Cancer Res 7 (2001) 1263-1272
12. Hui E.P., Pezzella F., Turley H., To K.F., Poon T.C., Zee B., et al. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res 8 (2002) 2595-2604
13. Chan A.T., Ngan R.K., Teo P.M., Lau W.H., Kwan W.H., Hui E.P., et al. Overall survival after concurrent cisplatin-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma. J Natl Cancer Inst 97 (2005) 536-539
14. Richardson M.C., Richardson D., Swinson D.E., Swain W.A., Cox G., and O'Byrne K.J. Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer. Lung Cancer 48 (2005) 47-57
15. Kelly L.M., Hill A.D., Kennedy S., Connolly E.M., Ramanath R., and Teh S. Lack of prognostic effect of Cox-2 expression in primary breast cancer on short-term follow-up. Eur J Surg Oncol 29 (2003) 707-710
16. Fux R., Schwab M., Thon K.P., Gleiter C.H., and Fritz P. Cyclooxygenase-2 expression in human colorectal cancer is unrelated to overall patient survival. Clin Cancer Res 11 (2005) 4754-4760
17. Jeon Y.T., Kang S., Kang D.H., Yoo K.Y., Park I.A., and Bang Y.J. Cyclooxygenase-2 and p53 expressions in endometrial cancer. Cancer Epidemiol Biomarkers Prev 13 (2004) 1538-1542
18. Seo S.S., Song Y.S., Kang D.H., Park I.A., Bang Y.J., Kang S.B., et al. Expression of cyclooxygenase-2 in association with clinicopathological prognostic factors and molecular markers in epithelial ovarian cancer. Gynecol Oncol 92 (2004) 927-935
19. Kim H.J., Wu H.G., Park I.A., and Ha S.W. High cyclooxygenase-2 expression is related with distant metastasis in cervical cancer treated with radiotherapy. Int J Radiat Oncol Biol Phys 55 (2003) 16-20
20. Sheehan K.M., O'Donoghue D.P., MacSweeney F., Conroy R.M., Fitzgerald D.J., and Murray F.E. The relationship between cyclooxygenase-2 expression and colorectal cancer. JAMA 282 (1999) 1254-1257
21. Ferrandina G., Distefano M., Zannoni G., Gessi M., Legge F., Maggiano N., et al. Increased cyclooxygenase-2 expression is associated with chemotherapy resistance and poor survival in cervical cancer patients. J Clin Oncol 20 (2002) 973-981
22. Ferrandina G., Zannoni G., Fagotti A., Fanfani F., Legge F., Maggiano N., et al. Increased cyclooxygenase-2 (COX-2) expression is associated with chemotherapy resistance and outcome in ovarian cancer patients. Annal Onc 13 (2002) 1205-1211
23. Nix P., Lind M., Greenman J., Stafford N., and Cawkwell L. Expression of Cox-2 protein in radioresistant laryngeal cancer. Ann Oncol 15 (2004) 797-801
24. Peng J.P., Chang H., Hwang C.F., and Hung W.C. Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with lymph node metastasis. Oral Oncol 41 (2005) 903-908
25. Chen W.C., Chen S.M., Lee K.F., Hwang T.Z., Jung S.M., Shau H., et al. Prediction of poor survival by cyclooxygenase-2 in patients with T4 nasopharyngeal cancer treated by radiation therapy: clinical and in vitro studies. Head Neck 27 Jun (2005) 503-512
26. Huang S.P., Wu M.S., Shun C.T., Wang H.P., Hsieh C.Y., and Kuo M.L. Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma. J Biomed Sci 12 (2005) 229-241
27. Palayoor S.T., Tofilon P.J., and Coleman C.N. Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells. Clin Cancer Res 9 (2003) 3150-3157
28. Zhong H., Willard M., and Simons J. NS398 reduces hypoxia-inducible factor (HIF)-1alpha and HIF-1 activity: multiple-level effects involving cyclooxygenase-2 dependent and independent mechanisms. Int J Cancer 112 (2004) 585-595