Effects of pharmacologic agents on bone in childhood: An editorial overview

Pediatrics

Volumn 119, Issue SUPPL. 2, 2007, Pages

  Klein, Gordon L ^a   Bachrach, Laura K ^b   Holm, Ingrid A ^c  

^a University of Texas Medical Branch School of Medicine   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Anabolic steroids; Antiepileptic drugs; Areal bone mineral density; Bisphosphonate; Glucocorticoids

Indexed keywords

ALENDRONIC ACID; ANDROGEN; ANTICONVULSIVE AGENT; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; DEXAMETHASONE; ESTROGEN; HUMAN GROWTH HORMONE; LACTOSE; OLPADRONIC ACID; PAMIDRONIC ACID; PHOSPHATE; PHOSPHORUS; PLACEBO; VITAMIN D; ZOLEDRONIC ACID;

ALBERS SCHOENBERG DISEASE; BONE; BONE DENSITOMETRY; BONE DENSITY; BONE FRAGILITY; BONE GROWTH; BONE MASS; BONE METASTASIS; BONE MINERALIZATION; BONE NECROSIS; BONE REMODELING; CHILD GROWTH; CLINICAL TRIAL; CONFERENCE PAPER; DRUG EFFECT; DUAL ENERGY X RAY ABSORPTIOMETRY; HEALTH CARE ORGANIZATION; HUMAN; MEDICAL RESEARCH; MEDICAL SOCIETY; NONHUMAN; OSSIFICATION; OSTEOGENESIS IMPERFECTA; OSTEOLYSIS; OSTEOPOROSIS; PRIORITY JOURNAL; UNSPECIFIED SIDE EFFECT;

ADOLESCENT; ANIMALS; ANTICONVULSANTS; BONE AND BONES; BONE DENSITY; BONE DEVELOPMENT; BONE DISEASES; CHILD; DENSITOMETRY; DIPHOSPHONATES; HORMONES; HUMANS; VITAMIN D DEFICIENCY;

EID: 33947185193     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2006-2023C     Document Type: Conference Paper

References (23)

1. Klein GL, Fitzpatrick LA, Langman CB, et al. The state of pediatric bone: summary of the ASBMR Pediatric Bone Initiative. J Bone Miner Res. 2005;20:2075-2081
2. Gafni RI, McCarthy EF, Hatcher T, et al. Recovery from osteoporosis through skeletal growth: early bone mass acquisition has little effect on adult bone density. FASEB J. 2002;16:736-738
3. Gafni RI, Weise M, Robrecht DT, et al. Catch-up growth is associated with delayed senescence of the growth plate in rabbits. Pediatr Res. 2001;50:618-623
4. Rauch F. Bone growth in length and width: the yin and yang of bone stability. J Musculoskelet Neuronal Interact. 2005;5:194-201
5. Sabbagh Y, Carpenter TO, Demay M. Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes. Proc Natl Acad Sci U S A. 2005;102:9637-9642
6. Sullivan J. Subject recruitment and retention: barriers to success. Appl Clin Trials. 2004. Available at: www.actmagazine.com/ appliedclinicaltrials/article/articleDetail.jsp?id=89608&searchString= Subject%20recruitment%20and%20retention. Accessed December 11, 2006
7. Oddone EZ, Olsen MK, Lindquist JH, et al. Enrollment in clinical trials according to patients' race: experience from the VA Cooperative Studies Program (1975-2000). Control Clin Trials. 2004;25:378-387
8. Bailey DA, McKay HA, Mirwald RL, Crocker PRE, Faulkner RA. A six-year longitudinal study of the relationship of physical activity to bone mineral accrual in growing children: the University of Saskatchewan Bone Mineral Accrual Study. J Bone Miner Res. 1999;14:1672-1679
9. Obesity and cardiovascular disease risk factors in black and white girls: the NHLBI Growth and Health Study. Am J Public Health. 1992;82:1613-1620
10. Wren TA, Liu X, Pitukcheewanont P, Gilsanz V. Bone acquisition in healthy children and adolescents: comparisons of dualenergy x-ray absorptiometry and computed tomography measures. J Clin Endocrinol Metab. 2005;90:1925-1928
11. Wren TAL, Liu X, Pitukcheewanont P, Gilsanz V. Bone densitometry in pediatric populations: discrepancies in the diagnosis of osteoporosis by DXA and CT. J Pediatr. 2005;146:776-779
12. Luckman SP, Hughes DE, Coxon FP, Russell RGG, Rogers MJ. JBMR Anniversary Classic: nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent posttranslational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res. 2005;20:1265-1274
13. Glorieux FH, Bishop NJ, Plotkin H, Chabot G, Lanoue G, Travers R. Cyclic administration of pamidronate in children with severe osteogenesis imperfecta. N Engl J Med. 1998;339:947-952
14. Munns CF, Rauch F, Zeitlin L, Fassier F, Glorieux FH. Delayed osteotomy but not fracture healing in pediatric osteogenesis imperfecta patients receiving pamidronate. J Bone Miner Res. 2004;19:1779-1786
15. Whyte MP, Wenkert D, Clements KL, McAlister WH, Mumm S. Bisphosphonate-induced osteopetrosis. N Engl J Med. 2003;349:457-463
16. Marini JC. Do bisphosphonates make children's bones better or brittle? N Engl J Med. 2003;349:423-426
17. Marini JC, Chernoff EJ, Letocha AD. Osteogenesis imperfecta. In: Cassidy SB, Allanson JE, eds. Management of Genetic Syndromes. New York, NY: Wiley and Sons, Inc; 2004:407-420
18. Burnham JM, Shults J, Semeao E, et al. Whole body BMC in pediatric Crohn's disease: independent effects of altered growth, maturation, and body composition. J Bone Miner Res. 2004;19:1961-1968
19. Leonard MB, Feldman HI, Shults J, Zemel BS, Foster BJ, Stallings VA. Long-term high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephritic syndrome. N Engl J Med. 2004;351:868-875
20. Misra M, Aggarwal A, Miller KK, et al. Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls. Pediatrics. 2004;114:1574-1583
21. Petty SJ, Paton LM, O'Brien TJ, et al. Effect of antiepileptic medication on bone mineral measures. Neurology. 2005;65:1358-1365
22. Hart DW, Herndon DN, Klein GL, et al. Attenuation of posttraumatic muscle catabolism and osteopenia by long-term growth hormone therapy. Ann Surg. 2001;233:827-834
23. Murphy KD, Thomas S, Mlcak RP, Chinkes DL, Klein GL, Herndon DN. Effects of long-term oxandrolone administration in severely burned children. Surgery. 2004;136:219-224