Effects of prostaglandin E1α cyclodestrin treatment on endothelial dysfunction in patients with systemic sclerosis

Journal of Hypertension

Volumn 25, Issue 4, 2007, Pages 793-797

  Giannattasio, Cristina ^a   Pozzi, MariaRosa ^a   Gradinali, Marco ^a   Montemerlo, Elisabetta ^a   Citterio, Francesca ^a   Maestroni, Silvia ^a   Fantini, Elena ^a   Failla, Monica ^a   Robuschi, Maria ^a   Bianco, Salvatore ^a   Mancia, Giuseppe ^a,b  

^a SAN GERARDO HOSPITAL   (Italy)

^b ISTITUTO AUXOLOGICO ITALIANO   (Italy)

Author keywords

Alfa 1 cycodestrin; Arterial vessel; Endothelium; Raynaud disease; Systemic sclerosis

Indexed keywords

GLYCERYL TRINITRATE; NITRIC OXIDE; PROSTAVASIN; ALPHA CYCLODEXTRIN DERIVATIVE; DRUG DERIVATIVE; PROSTAGLANDIN E1; PROSTAGLANDIN E1 ALPHA CYCLODEXTRIN; PROSTAGLANDIN E1-ALPHA-CYCLODEXTRIN; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ADULT; ARTERY DILATATION; ARTICLE; BLOOD FLOW; BLOOD VESSEL DIAMETER; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENDOTHELIUM; FEMALE; HEART RATE; HUMAN; PRIORITY JOURNAL; RADIAL ARTERY; SYSTEMIC SCLEROSIS; SYSTOLIC BLOOD PRESSURE; VASODILATATION; ANALYSIS OF VARIANCE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; DRUG EFFECT; EXHALATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; TREATMENT OUTCOME; VASCULAR ENDOTHELIUM;

ALPHA-CYCLODEXTRINS; ALPROSTADIL; ANALYSIS OF VARIANCE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; ENDOTHELIUM, VASCULAR; EXHALATION; FEMALE; HEART RATE; HUMANS; INFUSIONS, INTRAVENOUS; MIDDLE AGED; NITRIC OXIDE; RADIAL ARTERY; REGIONAL BLOOD FLOW; SCLERODERMA, SYSTEMIC; TREATMENT OUTCOME; VASODILATION; VASODILATOR AGENTS;

EID: 33947184833     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e328032784f     Document Type: Article

References (23)

1. Kawut SM, Taichman DB, Archer-Chicko CL, Palevsky HI, Kimmel SE. Hemodynamics and survival in patients with pulmonary arterial hypertension related to systemic sclerosis. Chest 2003; 123:344-350.
2. Diadzio M, Giovagnoni A, Pomponio G, Recanatini A, Della Costanza OP, Manzin A, Gabrielli A. Acute myocarditis associated with adenoviral infection in a patient with scleroderma. Clin Rheumatol 2003; 22:487-490.
3. Stacher G, Merio R, Budka C, Hneider C, Smolen J, Tappeiner G. Cardiovascular autonomic function antibodies and esophageal motor activity in patients with systemic sclerosis and mixed connettive tissue. J Rheumatol 2000; 27:692-697.
4. Steen VD, Follansbee WP, Conte CG, Medsger TA Jr. Thallium perfusion defects predict subsequent cardiac dysfunction in patients with systemic sclerosis. Arthritis Rheum 1996; 39:677-681.
5. Kottinen YT, Ruuttila P, Ceponis A, Sukura A, Hukka, Virtanen I. Vascular damage and lack of angiogenesis in systemic sclerosis. Clin Rheumatol 2003; 22:196-202.
6. Andersen GN, Mincheva-Nilsson L, Kazzam E, Klintland N, Petersson AS, Waldenstrom A, Caidahl K. Assessment of vascular function in systemic sclerosis: indications of the decrease of nitrate tolerance as a result of enhanced endothelial nitric oxide production. Arthritis Rheum 2002; 46:1324-1332.
7. Kharitonov SA, Cailes JB, Black CM, du Bois RM, Barnes PJ. Decreased nitric oxide in exhaled air of patients with systemic sclerosis and pulmonary hypertension. Thorax 1997; 52:1051-1055.
8. Subcommittee for Scleroderma Criteria of the American Rheumatism Association: Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980; 23:581-590.
9. Hoecks APG, Brands PJ, Reneman S. Assessment of the arterial distension waveform using Doppler signal processing. J Hypertens 1991; 10:979-984.
10. Hoecks A, Brands PJ, Smeets FA, Reneman RS. Assessment of the distensibility of superficial arteries. Ultrasound Med Biol 1990; 16:121-128.
11. Hoecks AP, Willekes C, Boutouierye P, Brands PJ, Willigers JM, Reneman RS. Automated detection of local artery wall thicknes based on M-line signal processing. Ultrasound Med Biol 1997; 23:1017-1023.
12. Joannides R, Haefeli WE, Linder L. Nitric oxide is responsible for flow dependent dilation of human pheripheral conduit arteries in vivo. Circulation 1995; 91:1314-1319.
13. Deanfield J, Donald A, Ferri C, Giannattasio C, Halcox J, Halligan S, et al. Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. J Hypertens 2005; 23:7-17
14. Martin MFR, Dowd PM, Ring EFJ, Cooke ED, Dieppe PA, Kirby JTD. Prostaglandin E1 infusions for vascular insufficiency in progressive systemic sclerosis. Ann Rheum Dis 1981; 40:350-354.
15. Morhland JS, Porter JM, Smith EA, Belch J, Simms MH. A multi-centric placebo-controlled double blind study of prostaglandin E1 in Raynaud's syndrome. Ann Rheum Dis 1985; 44:754-760.
16. Mazzone A, Faggioli P, Cusa C, Stefanin C, Rondena M, Morelli B. Effects of iloprost on adhesion molecules F1 +2 in pheripheral ischaemia. Eur J Clin Invest 2002; 32:882-888.
17. Freedman RR, Girgis R, Mayes MD. Abnormal responses to endothelial agonists in Raynaud's phenomenon and scleroderma. J Rheumatol 2001; 28:119-121.
18. Cheng KS, Tiwari A, Boutin A, Denton CP, Morris R, Hamilton G, Seifalian AM. Carotid and femoral arterial wall mechanics in scleroderma. Rheumatology (Oxford) 2003; 11:1299-1305.
19. Gardinali M, Pozzi MR, Bernareggi M, Montani N, Allevi E, Catena L, et al. Treatment of Raynaud's phenomenon with intravenous prostaglandin E1 α-cyclodestrin improves endothelial cell injury in systemic sclerosis. J Rheumatol 2001; 28:786-794.
20. Mavrikakis ME, Lekakis JP, Papamichael CM, Kostopoulos CH, Stamatelopoulos SF. Ascorbic acid does not improve endothelium-dependent flow-mediated dilatation of the brachial artery in patients with Raynaud's phenomenon secondary to systemic sclerosis. Int J Vitamin Nutr Res 2003; 73:3-7.
21. Giannattasio C, Failla M, Emanuelli G, Grappiolo A, Boffi L, Corsi D, et al. Local effects of atherosclerotic plaque on arterial distensibility. Hypertension 2001; 38:1177-1180.
22. Andersen GN, Mincheva-Nilsson L, Kazzam E, Nyberg G, Klintland N, Petersson AS, et al. Assessment of vascular function in systemic sclerosis: indications of the development of nitrate tolerance as a result of enhanced endothelial nitric oxide production. Arthritis Rheum 2002; 46:1324-1332.
23. Lekakis J, Mavrikakis M, Papamichael C, Papazoglou S, Economou O, Scotiniotis I, et al. Short-term estrogen administration improves abnormal endothelial function in women with systemic sclerosis and Raynaud's phenomenon. Am Heart J 1998; 136:905-912.