Renal albumin handling: A look at the dark side of the filter

Kidney International

Volumn 71, Issue 6, 2007, Pages 479-481

  Gekle, M ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN;

GLOMERULUS FILTRATION; HUMAN; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE CELL; KIDNEY TUBULE EXCRETION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RENAL ALBUMIN HANDLING; REVIEW; TECHNIQUE;

EID: 33947183451     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002123     Document Type: Note

References (9)

1. Gekle M. Renal tubule albumin transport. Annu Rev Physiol 2005; 67: 573-594.
2. Lambers Heerspink HJ, Brinkman JW, Bakker SJ et al. Update on microalbuminuria as a biomarker in renal and cardiovascular disease. Curr Opin Nephrol Hypertens 2006; 15: 631-636.
3. Nagase M, Shibata S, Yoshida S et al. Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker. Hypertension 2006; 47: 1-10.
4. Birn H, Christensen EI. Renal albumin absorption in physiology and pathology. Kidney Int 2006; 69: 440-449.
5. Peters T. Serum albumin. Adv Protein Chem 1985; 37: 161-245.
6. Tojo A, Endou H. Intrarenal handling of proteins in rats using fractional micropuncture technique. Am J Physiol 1992; 263: F601-F606.
7. Eppel GA, Osicka TM, Pratt LM et al. The return of glomerular-filtered albumin to the rat renal vein. Kidney Int 1999; 55: 1861-1870.
8. Russo LM, Sandoval RM, McKee M et al. The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int 71: 504-513.
9. Christensen EI, Birn H. Megalin and cubilin: multifunctional endocytic receptors. Nat Rev Mol Cell Biol 2002; 3: 256-266.