Differences in the chemical composition of the particulate phase of inhaled and exhaled cigarette mainstream smoke

Beitrage zur Tabakforschung International/ Contributions to Tobacco Research

Volumn 22, Issue 4, 2007, Pages 290-302

  Moldoveanu, Serban C ^a   St Charles, F Kelley ^b  

^a R J REYNOLDS TOBACCO COMPANY   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33947181972     PISSN: 0173783X     EISSN: 16129237     Source Type: Journal    
DOI: 10.2478/cttr-2013-0834     Document Type: Article

References (38)

1. Lehmann, K.B. : Untersuchungen im Rauche des Tabaks [Investigation of the smoke from tobacco]; München med. Wochenschrift LV (1908) 723-725.
2. Isaac, R.F. and MJ. Rand: Cigarette smoking and plasma levels of nicotine; Nature 236 (1972) 308-310.
3. McAughey, J.J., O.K. Knight, A. Black, and C.J. Dickens: Environmental tobacco smoke retention in humans from measurements of exhaled smoke composition; Inhal. Toxicol. 6 (1994) 615-631.
4. Armitage, A.K., C.T. Dollery, C.F. George, T.H. Houseman, PJ. Lewis, and D.M. Turner: Absorbtion and metabolism of nicotine from cigarettes; Brit. Med. J. 4(1975)313-316.
5. Gori, G.B. and N.L. Benowitz, and C.J. Lynch: Mouth versus deep airways absorption of nicotine in cigarette smokers; Pharmacol. Biochem. Behav. 25 (1986) 1181-1184.
6. Armitage, A.K., M. Dixon, B.E. Frost, D.C. Mariner, and N.M. Sinclair: The effect of tobacco blend additives on the retention of nicotine and solanesol in the human respiratory tract and on subsequent plasma nicotine concentrations during cigarette smoking; Chem. Res. Toxicol. 17 (2004) 537-544.
7. Armitage, A.K., M. Dixon, B.E. Frost, D.C. Mariner, and N.M. Sinclair: The effect of inhalation volume and breath-hold duration on the retention of nicotine and solanesol in the human respiratory tract and on subsequent plasma nicotine concentrations during cigarette smoking; Beitr. Tabakforsch. Int. 21 (2004) 240-249.
8. Lehmann, K.B.: Chemische und toxikologische Untersuchung des Tabaks, des Tabakrauchs und des Tabakrauchens [Chemical and toxicological study on tobacco, tobacco smoke and tobacco smoking]; Arch. Hyg. 68 (1909) 321-420.
9. Broday, D.M. and P.G. Georgopoulos: Growth and deposition of hygroscopic particulate matter in the human lung; Aerosol. Sci. Tech. 34 (2001) 144-159.
10. Davies, C.N.: Deposition of inhaled particles in man; Chemistry and Industry (1974) 441-444.
11. Robinson, R.J. and C.P. Yu: Deposition of cigarette smoke particles in the human respiratory tract; Aerosol. Sci. Tech. 34 (2001) 202-215.
12. Hinds, W., M.W. First, G.L. Huber, and J.W. Shea: A method for measuring the deposition of cigarette smoke during smoking; Am. Ind. Hyg. Assoc. J. 44 (1983) 113-118.
13. Dalhamn, T., M-L. Edfors, and R. Rylander: Mouth absorption of various compounds in cigarette smoke; Arch. Environ. Health. 16 (1968) 831-835.
14. Dalhamn, T., M-L. Edfors, and R. Rylander: Retention of cigarette smoke components in human lungs; Arch. Environ. Health. 17 (1968) 746-748.
15. Baker, R.R. and M. Dixon: The retention of tobacco smoke constituents in the human respiratory tract; Inhal. Toxicol. 18 (2006) 255-294.
16. Laskowski, K.: Components of tobacco smoke and their absorption in the respiratory system of the smoker; Rocz. Państw. Zak. Hig. [Ann. Natl. Inst. Hyg.] 2 (1951) 139-160.
17. Haagen-Smit, A.J., M.F. Brunelle, and J. Hara: Nitrogen oxide content of smokes from different types of tobacco; A. M. A. Arch. Ind. Health 20 (1959) 399-400.
18. Egle, J.L. Jr: Retention of inhaled acetaldehyde in man; J. Pharmacol. Experim. Therapeutics 174 (1970) 14-19.
19. Deliconstantinos, G., V. Villiotou, and J.C. Stavrides: Scavenging effects of hemoglobin and related heme containing compounds on nitric oxide, reactive oxidants and carcinogenic nitroso compounds of cigarette smoke. A new method for protection against the dangerous cigarette constituents; Anticancer Res. 14 (1995) 2717-2726.
20. Ingebrethsen, B.J.: The physical properties of mainstream cigarette smoke and their relationship to deposition in the respiratory tract; in: Extrapolation of dosimetric relationships for inhaled particles and gases, edited by J.D. Crapo, E.D. Smolko, F.J. Miller, J.A. Graham, and A.W. Hayes, Chap. 12, New York, NY, Academic Press, 1989, pp. 125-141.
21. Gordon, S.M., L.A. Wallace, M.C. Brinkman, P.J. Callahan, and D.V. Kenny: Volatile organic compounds as breath biomarkers for active and passive smoking; Environ. Health Perspect. 110 (2002) 689-698.
22. Chaudhury, R., E. Levingston, L. Thomson, K. MacLeod, C. McSharry, J. Hossein, A. McKay, and N.C. Thomson: The effect of cigarette smoking on exhaled breath condensate prostaglandin E2 levels in asthma; American Thoracic Society/American Lung Association (ATS/ALA) Meeting Abstracts, Atlanta, May 18-23, 2002.
23. Garey, K.W., M. Neuhauser, M.M. Rafice, A.L. Robbins, L.H. Danziger, and I. Rubinstein: Protein, nitrate/nitrite, and cytokine concentration in exhaled breath condensate of young smokers; Amer. J. Respir. Critical CareMed. 161 (2000) A175.
24. Chaudhury, R., E. Levingston, L. Thomson, C. McSharry, K. MacLeod, J. Hossein, A. McKay, and N.C. Thomson: Nitrite levels in the breath condensate of smoking asthmatics; American Thoracic Society/American Lung Association (ATS/ALA) Meeting Abstracts, Atlanta, May 18-23, 2002.
25. Corradi, M., I. Rubinstein, R. Andreoli, P. Manini, A. Caglieri, D. Poli, R. Alinovi, and A. Mutti: Aldehydes in exhaled breath condensate of patients with chronic obstructive pulmonary disease; Amer. J. Respir. Critical Care Med. 167 (2003) 1380-1386.
26. Risby, T.H.: Further discussion on breath condensate analysis; Amer. J. Respiratory and Critical Care Med. 167 (2003) 1301-1302.
27. Doyen, K., M. Carey, R.S.T. Linforth, M. Marin, and A.J. Taylor: Volatile release from an emulsion headspace and in-mouth studies; J. Agric. Food Chem. 49 (2001) 804-810.
28. Scheideler, L., H.G. Manke, U. Schwulera, O. Inacker, and H. Hammerle: Detection of nonvolatile macromolecules in breath, a possible diagnostic tool? Amer. Rev. Respir. Dis. 148 (1993) 778-784.
29. Holzer, G.J., Oro, and W. Bertsch: Gas chromatographic-mass spectrometric evaluation of exhaled tobacco smoke; J. Chromatogr. 126 (1976) 771-785.
30. Pillsbury, H.C., C.C. Bright, K.J. O'Connor, and F.H. Irish: Tar and nicotine in cigarette smoke; J. Assoc. Off. Anal. Chem. 52, (1969) 458-462.
31. ISO 10315: Cigarettes - determination of nicotine in smoke condensates - gas chromatographic method; International Organization for Standardization, Geneva, Switzerland, First Edition 1991-08-01, 1991 (E).
32. th Tobacco Science Research Conference, Program Booklet and Abstracts, Vol. 55, Paper No. 92, 2001, pp. 73-74.
33. th Tobacco Science Research Conference, Program Booklet and Abstracts, Vol.58, Paper No. 8, 2004, p 25.
34. Borgerding, M.F., J.A. Bodnar, and D.E. Wingate, (Ed.): The 1999 Massachusetts benchmark study, final report (July 24, 2000), Vol. 4; R. J. Reynolds Tobacco Company, Winston-Salem, 2000.
35. Moldoveanu, S.C. and V. David: Sample preparation in chromatography; Elsevier, Amsterdam, 2002, pp. 58-60.
36. Hansch, C., A. Leo, and D. Hoekman: Exploring QSAR, hydrophobic, electronic and steric constants; ACS Professional Reference Book, Washington, DC 1995.
37. Broto, P., G. Moreau, and C. Vandyke: Molecular structure, perception, autocorrelation descriptor and SAR studies. System atomic contributions for the calculation of the n-octanol/water partition coefficients; Eur. J. Med. Chem. Chim. Theor. 19 (1984) 71-78.
38. Viswanadhan, V.N., A.K. Ghose, G.R. Ravankar, and R.K. Robins: Atomic physicochemical parameters for three-dimensional structure-directed quantitative structure-activity relationship IV; additional parameters for hydrophobic and dispersive interactions and their application for an automated superposition of certain naturally occurring nucleoside antibiotics; J Chem. Inf. Comput. Sci. 29 (1989) 163-172.