Cerebral pachyleptomeningitis associated with MPO-ANCA induced by PTU therapy

Internal Medicine

Volumn 46, Issue 5, 2007, Pages 247-250

  Abe, Takato ^a   Nogawa, Shigeru ^a   Tanahashi, Norio ^a   Shiraishi, Junichi ^a   Ikeda, Eiji ^a   Suzuki, Norihiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

MPO ANCA; Pachyleptomeningitis; PTU

Indexed keywords

ANTIDEPRESSANT AGENT; DEXAMETHASONE; GADOLINIUM; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY; PREDNISOLONE; PROPYLTHIOURACIL; THIAMAZOLE;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; BLOOD ANALYSIS; BRAIN BIOPSY; BRAIN FUNCTION; CASE REPORT; CONTRAST ENHANCEMENT; DEPRESSION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FRONTAL LOBE; GRAVES DISEASE; HAND MOVEMENT; HUMAN; HUMAN TISSUE; HYPERREFLEXIA; LEG MUSCLE; MENINGITIS; MOTOR DYSFUNCTION; MUSCLE WEAKNESS; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PACHYLEPTOMENINGITIS; PARIETAL LOBE; STEROID THERAPY;

ADULT; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; ANTITHYROID AGENTS; ARACHNOID; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; GRAVES DISEASE; HUMANS; MAGNETIC RESONANCE IMAGING; MENINGITIS; PEROXIDASE; PIA MATER; PREDNISOLONE; PROPYLTHIOURACIL;

EID: 33947169323     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.46.1859     Document Type: Article

References (15)

1. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 9-1999. A 74-year-old woman with hydrocephalus and pleocytosis. N Engl J Med 340: 945-953, 1999.
2. Nagashima T, Maguchi S, Terayama Y, et al. P-ANCA-positive Wegener's granulomatosis presenting with hypertrophic pachymeningitis and multiple cranial neuropathies: case report and review of literature. Neuropathology 20: 23-30, 2000.
3. Yoritaka A, Tsukamoto T, Ohta K, Kishida S. A clinical study of pachymeningitis. No To Shinkei (Brain and Nerve) 54: 235-240, 2002 (in Japanese, Abstract in English).
4. Funauchi M, Yoo BS, Sugiyama M, et al. A case of rheumatoid meningitis positive for perinuclear antineutrophil cytoplasmic antibody. Ann Rheum Dis 59: 1001-1002, 2000.
5. Kono H, Inokuma S, Nakayama H, Yamazaki J. Pachymeningitis in microscopic polyangiitis (MPA): a case report and a review of central nervous system involvement in MPA. Clin Exp Rheumatol 18: 397-400, 2000.
6. Furukawa Y, Matsumoto Y, Yamada M. Hypertrophic pachymeningitis as an initial and cardinal manifestation of microscopic polyangiitis. Neurology 63: 1722-1724, 2004.
7. Yakushiji Y, Kurohara K, Toda S, Abe M, Kuroda Y. A case of hypertrophic spinal pachymeningitis associated with MPO-ANCA. Rinsho Shinkeigaku 42: 873-877, 2002 (in Japanese, Abstract in English).
8. Kitahara T, Hiromura K, Maezawa A, et al. Case of propylthiouracil-induced vasculitis associated with anti-neutrophil cytoplasmic antibody (ANCA); review of literature. Clin Nephrol 47: 336-340, 1997.
9. Dolman KM, Gans RO, Vervaat TJ, et al. Vasculitis and antineutrophil cytoplasmic autoantibodies associated with propylthiouracil therapy. Lancet 342: 651-652, 1993.
10. Stankus SJ, Johnson NT. Propylthiouracil-induced hypersensitivity vasculitis presenting as respiratory failure. Chest 102: 1595-1596, 1992.
11. 14C]propylthiouracil in human polymorphonuclear leukocytes. Biochem Pharmacol 28: 2289-2296, 1979.
12. Lee E, Hirouchi M, Hosokawa M, Sayo H, Kohno M, Kariya K. Inactivation of peroxidases of rat bone marrow by repeated administration of propylthiouracil is accompanied by a change in the heme structure. Biochem Pharmacol 37: 2151-2153, 1988.
13. Ito K, Fujii H, Sumitomo H, et al. A case of spinal pachymeningitis associated with MPO-ANCA during treatment with antithyroid drug (abstract). Nihon Jinzo Gakkaishi 36: 1354, 1994 (in Japanese).
14. Takahashi K, Kobayashi S, Okada K, Yamaguchi S. Pachymeningitis with a perinuclear antineutrophil cytoplasmic antibody: response to pulse steroid. Neurology 50: 1190-1191, 1998.
15. Meilof JF. p-ANCA and hypertrophic pachymeningitis. Neurology 52: 430-431, 1999.