Isolation of two regions on rat chromosomes 5 and 18 affecting mammary cancer susceptibility

International Journal of Cancer

Volumn 120, Issue 8, 2007, Pages 1678-1683

  Stieber, Daniel ^a   Piessevaux, Géraldine ^a   Rivière, Michèle ^a   Laes, Jean François ^a,b   Quan, Xiaojiang ^a,c   Szpirer, Josiane ^a   Szpirer, Claude ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Biovallée ^*  (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Cancer susceptibility; Congenics; Haplotype; Mammary cancer; Rat

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; ESTROGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER SUSCEPTIBILITY; CHROMOSOME 18; CHROMOSOME 5; CHROMOSOME ISOLATION; CHROMOSOME MOSAICISM; CONGENIC STRAIN; CONTROLLED STUDY; FEMALE; HAPLOTYPE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RAT; STRAIN DIFFERENCE; WISTAR KYOTO RAT;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANIMALS, CONGENIC; CARCINOGENS; CHROMOSOME MAPPING; CHROMOSOMES; CROSSES, GENETIC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; MAMMARY NEOPLASMS, EXPERIMENTAL; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE; RATS; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY;

EID: 33947156774     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22400     Document Type: Article

References (35)

1. Martin AM, Weber BL. Genetic and hormonal risk factors in breast cancer. J Natl Cancer Inst 2000;92:1126-35.
2. Nathanson KL, Weber BL. "Other" breast cancer susceptibility genes: searching for more holy grail. Hum Mol Genet 2001;10:715-20.
3. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennett LM, Ding W. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;26:66-71.
4. Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S, Bennett LM, Haugen-Strano A, Swensen J, Miki Y. BRCA1 mutations in primary breast and ovarian carcinomas. Science 1994;266:120-2.
5. Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995;378:789-92.
6. Tavtigian SV, Simard J, Rommens J, Couch F, Shattuck-Eidens D, Neuhausen S, Merajver S, Thorlacius S, Offit K, Stoppa-Lyonnet D, Belanger C, Bell R, et al. The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nat Genet 1996;12:333-7.
7. Claus EBJ, Schildkraut M, Thompson WD, Risch NJ. The genetic attributable risk of breast and ovarian cancer. Cancer 1996;77:2318-24.
8. Claus EBJ, Schildkraut J, Iversen ES, Jr, Berry D, Parmigiani G. Effect of BRCA1 and BRCA2 on the association between breast cancer risk and family history. J Natl Cancer Inst 1998;90:1824-9.
9. Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Parl FF, Moore JH. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet 2001;69:138-47.
10. Pharoah PD, Antonoiu A, Bobrow M, Zimmern RL, Easton DF, Ponder BA. Polygenic susceptibility to breast cancer and implication for prevention. Nat Genet 2002;31:33-6.
11. The CHEK2-Breast Cancer Consortium. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 2002;31:55-9.
12. Dahlman I, Eaves IA, Kosoy R, Morrison VA, Reward J, Gough SC, Allahabadia A, Franklyn JA, Tuomilehto J, Tuomilehto-Wolf E, Cucca F, Guja C, et al. Parameters for reliable results in genetic association studies in common disease. Nat Genet 2002;30:149-50.
13. Gould MN. Cellular and molecular aspects of the multistage progression of mammary carcinogenesis in humans and rats. Semin Cancer Biol 1993; 4:161-9.
14. Gould MN. Rodent models for the study of aetiology, prevention and treatment of breast cancer. Semin Cancer Biol 1995;6:147-52.
15. Russo IH, Russo J. Mammary gland neoplasia in long-term rodent studies. Environ Health Perspect 1996;104:938-67.
16. Russo J, Russo IH. Experimentally induced mammary tumors in rats. Breast Cancer Res Treat 1996;39:7-20.
17. Shepel LA, Gould MN. The genetic components of susceptibility to breast cancer in the rat. Prog Exp Tumor Res 1999;3:158-69.
18. Isaacs JT. Genetic control of resistance to chemically induced mammary adenocarcinogenesis in the rat. Cancer Res 1986;46:3958-63.
19. Isaacs JT. Inheritance of a genetic factor from the Copenhagen rat and the suppression of chemically induced mammary adenocarcinogenesis. Cancer Res 1988;48:2204-13.
20. Gould MN. Inheritance and site of expression of genes controlling susceptibility to mammary cancer in a inbred rat model. Cancer Res 1986; 46:1199-202.
21. Hsu LC, Kennan WS, Shepel LA, Jacob HJ, Szpirer C, Szpirer J, Lander ES, Gould MN. Genetic identification of Mcs-1, a rat mammary carcinoma suppressor gene. Cancer Res 1994;54:2765-70.
22. Shepel LA, Lan H, Haag JD, Brasic GM, Gheen ME, Simon JS, Hoff P, Newton MA, Gould MN. Genetic identification of multiple loci that control breast cancer susceptibility in the rat. Genetics 1998;149:289-99.
23. Lan H, Kendziorski CM, Haag JD, Shepel LA, Newton MA, Gould MN. Genetic loci controlling breast cancer susceptibility in the Wistar-Kyoto rat. Genetics 2001;157:331-9.
24. Haag JD, Shepel LA, Kolman BD, Monson DM, Benton ME, Watts KT, Waller JL, Lopez-Guajardo CC, Samuelson DJ, Gould MN. Congenic rats reveal three independent Copenhagen alleles within the Mcs1 quantitative trait locus that confer resistance to mammary cancer. Cancer Res 2003;63:5808-12.
25. Samuelson DJ, Haag JD, Lan H, Monson DM, Shultz MA, Kolman BD, Gould MN. Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats. Carcinogenesis 2003;9:1455-60.
26. Gould KA, Tochacek M, Schaffer BS, Reindl TM, Murrin CR, Lachel CM, VanderWoude EA, Pennington KL, Flood LA, Bynote KK, Meza JL, Newton MA, et al. Genetic determinants of susceptibility to estrogen-induced mammary cancer in the ACI rat: mapping of Emca1 and Emca2 to chromosomes 5 and 18. Genetics 2004;168: 2113-25.
27. Hitzeman R, Malmanger B, Cooper S, Coulombe S, Reed C, Demarest K, Koyner J, Cipp L, Flint J, Talbot C, Rademacher B, Buck K et al. Multiple cross mapping markedly improves the localization of a QTL for ethanol-induced activation. Genes Brain Behav 2002;1:214-22.
28. Park YG, Zhao X, Lesueur F, Lowy DR, Lancaster M, Pharoah P, Qian X, Hunter KW. Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Nat Genetics 2005;37:1055-62.
29. Quan X, Laes JF, Stieber D, Riviere M, Russo J, Wedekind D, Coppieters W, Farnir F, Georges M, Szpirer J, Szpirer C. Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat. Mamm Genome 2006;17:310-21.
30. Greenhouse DD, Festing MFW, Hasan S, Cohen AL. Catalogue of inbred strains of rats. In: Hedrich HHJ. Genetic monitoring of inbred strains of rats. New York: Gustav Fischer Verlag, 1990.410-86.
31. Huggins CB, Ueda N, Wiessler M. N-Nitroso-N-methylurea elicits mammary cancer in resistant and sensitive rat strains. Proc Natl Acad Sci USA 1981:78:1185-8.
32. Samuelson DJ, Aperavich BA, Haag JD, Gould MN. Fine mapping reveals multiple loci and a possible epistatic interaction within the mammary carcinoma susceptibility quantitative trait locus Mcs5. Cancer Res 2005;65:9637-42.
33. Laes JF, VanVooren P, Szpirer J, Szpirer C. Assignment of the cyclin-dependent kinase inhibitor genes Cdkn2a and Cdkn2b to rat chromosome bands 5q32-q34 and 5q31-q33, respectively by fluorescence in situ hybridization, using small PCR-generated probes. Cytogenet Cell Genet 1998;81:290-1.
34. Helou K, Lü XC, Montelius-Alatalo K, Stahl F, Klinga-Levan K, Levan G, Röhme D. A dual-color FISH framework map for the characterization of the Sai1 tumor suppression region of rat chromosome 5. Genes Chrom Cancer 2000;27:362-72.
35. Borg A, Sandberg T, Nilsson K, Johannsson O, Klinker M, Masback A, Westerdahl J, Olsson H, Ingvar C. High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families. J Natl Cancer Inst 2000;92:1260-6.