Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C

Journal of Hepatology

Volumn 46, Issue 4, 2007, Pages 664-673

  El Karef, Amro ^a   Kaito, Masahiko ^a   Tanaka, Hideaki ^a   Ikeda, Kazuo ^b   Nishioka, Tomohiro ^a   Fujita, Naoki ^a   Inada, Hiroyasu ^a   Adachi, Yukihiko ^a   Kawada, Norifumi ^b   Nakajima, Yuji ^b   Imanaka Yoshida, Kyoko ^a   Yoshida, Toshimichi ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Hepatic stellate cells; In situ hybridization; Interface hepatitis; Myofibroblast; Splice variants; Tenascin C

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBRONECTIN; FIBRONECTIN 3; MESSENGER RNA; MONOCLONAL ANTIBODY; TENASCIN; UNCLASSIFIED DRUG;

ADULT; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CELL CULTURE; CELL ISOLATION; CLINICAL ARTICLE; CORRELATION FUNCTION; FEMALE; FETUS; FIBROGENESIS; HEPATITIS C; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER; LIVER CELL; LIVER FIBROSIS; LIVER NECROSIS; MALE; MYOFIBROBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PARAMETER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; RAT; STAINING; STELLATE CELL; UPREGULATION;

ACTINS; ADULT; ALTERNATIVE SPLICING; ANIMALS; ANTIBODIES, MONOCLONAL; CELLS, CULTURED; CHRONIC DISEASE; EPITOPE MAPPING; FEMALE; FIBROBLASTS; HEPATITIS; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; RATS; RATS, WISTAR; STAINING AND LABELING; TENASCIN; VARIATION (GENETICS);

EID: 33947155191     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2006.10.011     Document Type: Article

References (37)

1. Ramadori G., Schwogler S., Veit T., Rieder H., Chiquet-Ehrismann R., Mackie E.J., et al. Tenascin gene expression in rat liver and in rat liver cells. In vivo and in vitro studies. Virchows Arch B Cell Pathol Incl Mol Pathol 60 (1991) 145-153
2. Van Eyken P., Sciot R., and Desmet V.J. Expression of the novel extracellular matrix component tenascin in normal and diseased human liver. An immunohisto-chemical study. J Hepatol 11 (1990) 43-52
3. Yamada S., Ichida T., Matsuda Y., Miyazaki Y., Hatano T., Hata K., et al. Tenascin expression in human chronic liver disease and in hepatocellular carcinoma. Liver 12 (1992) 10-16
4. Van Eyken P., Geerts A., De Bleser P., Lazou J.M., Vrijsen R., Sciot R., et al. Localization and source of the extracellular matrix protein tenascin in normal and fibrotic rat liver. Hepatology 15 (1992) 909-916
5. Knittel T., Kobold D., Saile B., Grundmann A., Neubauer K., Piscaglia F., et al. Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology 117 (1999) 1205-1221
6. Jiang F., Parsons C.J., and Stefanovic B. Gene expression profile of quiescent and activated rat hepatic stellate cells implicates Wnt signaling pathway in activation. J Hepatol 45 (2006) 401-409
7. Chiquet-Ehrismann R., and Chiquet M. Tenascins: regulation and putative functions during pathological stress. J Pathol 200 (2003) 488-499
8. Jones F.S., and Jones P.L. The tenascin family of ECM glycoproteins: structure, function, and regulation during embryonic development and tissue remodeling. Dev Dyn 218 (2000) 235-259
9. Mighall A.J., Thompson J., Hume W.J., Markham A.F., and Robinson P.A. Human tenascin-C: Identification of a novel type III repeat in oral cancer and of novel splice variants in normal, malignant and reactive oral mucosae. Int J Cancer 72 (1997) 236-240
10. Joester A., and Faissner A. The structure and function of tenascins in the nervous system. Matrix Biol 20 (2001) 13-22
11. Mackie E.J., and Tucker R.P. Tenascin in bone morphogenesis: expression by osteoblasts and cell type-specific expression of splice variants. J Cell Sci 103 (1992) 765-771
12. Borsi L., Carnemolla B., Nicolo G., Spina B., Tanara G., and Zardi L. Expression of different tenascin isoforms in normal, hyperplastic and neoplastic human breast tissues. Int J Cancer 52 (1992) 688-692
13. Hindermann W., Berndt A., Borsi L., Luo X., Hyckel P., Katenkamp D., et al. Synthesis and protein distribution of the unspliced large tenascin-C isoform in oral squamous cell carcinoma. J Pathol 189 (1999) 475-480
14. Matsumoto K., Hiraiwa N., Yoshiki A., Ohnishi M., and Kusakabe M. Tenascin-C expression and splice variant in habu snake venom-induced glomerulonephritis. Exp Mol Pathol 72 (2002) 186-195
15. Tsunoda T., Inada H., Kalembeyi I., Imanaka-Yoshida K., Sakakibara M., Okada R., et al. Involvement of large tenascin-C splice variants in breast cancer progression. Am J Pathol 162 (2003) 1857-1867
16. Tamaoki M., Imanaka-Yoshida K., Yokoyama K., Nishioka T., Inada H., Hiroe M., et al. Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury. Am J Pathol 167 (2005) 71-80
17. Tanaka H., El-karef A., Kaito M., Kinoshita N., Fujita N., Horiike S., et al. Circulating level of large splice variants of tenascin-C is a marker of piecemeal necrosis activity in patients with chronic hepatitis C. Liver Int 26 (2006) 311-318
18. Imanaka-Yoshida K., Hiroe M., Yasutomi Y., Toyozaki T., Tsuchiya T., Noda N., et al. Tenascin-C is a useful marker for disease activity in myocarditis. J Pathol 197 (2002) 388-394
19. Ishak K.G., Bapitesta A., Bianchi L., Callea F., DeGroote J., Gudat F., et al. Histological grading and staging of chronic hepatitis. J Hepatol 22 (1995) 696-699
20. Bedossa P., Poynard T., and METAVIR Cooperative Study Group. An algorithm for the grading of activity in chronic hepatitis C. Hepatology 24 (1996) 289-293
21. Hubscher S.G. Histological grading and staging in chronic hepatitis: clinical applications and problems. J Hepatol 29 (1998) 1015-1022
22. Kalembey I., Yoshida T., Iriyama K., and Sakakura T. Analysis of tenascin mRNA expression in the murine mammary gland from embryogenesis to carcinogenesis: an in situ hybridization study. Int J Dev Biol 41 (1997) 569-573
23. Yoshida T., Matsumoto E., Hanamura N., Kalembeyi I., Katsuta K., Ishihara A., et al. Co-expression of tenascin and fibronectin in epithelial and stromal cells of benign lesions and ductal carcinomas in the human breast. J Pathol 182 (1997) 421-428
24. Hanamura N., Yoshida T., Matsumoto E., Kawarada Y., and Sakakura T. Expression of fibronectin and tenascin-C mRNA by myofibroblasts, vascular cells and epithelial cells in human colon adenomas and carcinomas. Int J Cancer 73 (1997) 10-15
25. Ikeda K., Wakahara T., Wang Y.Q., Kadoya H., Kawada N., and Kaneda K. In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation. Hepatology 29 (1999) 1760-1767
26. Murakami K., Abe T., Miyazawa M., Yamaguchi M., Masuda T., Matsuura T., et al. Establishment of a new human cell line, LI90, exhibiting characteristics of hepatic Ito (fat-storing) cells. Lab Invest 72 (1995) 731-739
27. Balza E., Siri A., Ponassi M., Caocci F., Linnala A., Virtanen I., et al. Production and characterization of monoclonal antibodies specific for different epitopes of human tenascin. FEBS lett 332 (1993) 39-43
28. Ramadori G., and Saile B. Inflammation, damage repair, immune cells, and liver fibrosis: specific or nonspecific, this is the question. Gastroenterology 127 (2004) 870-882
29. Pinzani M., Rombouts K., and Colagrande S. Fibrosis in chronic liver diseases: diagnosis and management. J Hepatol 42 (2005) S22-S36
30. Bataller R., and Brenner D.A. Liver fibrosis. J Clin Invest 115 (2005) 209-218
31. Ramadori G., and Saile B. Portal tract fibrogenesis in the liver. Lab Invest 84 (2004) 153-159
32. Wallner K., Shah K.S., and Sharifi B.G. Balloon catheterization induces arterial expression of new tenascin-C isoforms. Atherosclerosis 161 (2002) 75-83
33. Chung C.Y., Murphy-Ullrich J.E., and Erickson H.P. Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II. Mol Biol Cell 7 (1996) 883-892
34. Adams M., Jones J.L., Walker R.A., Pringle J.H., and Bell S.C. Changes in tenascin-C isoform expression in invasive and preinvasive breast disease. Cancer Res 62 (2002) 3289-3297
35. Siri A., Knauper V., Veirana N., Caocci F., Murphy G., and Zardi L. Different Susceptibility of small and large human tenascin-C isoforms to degradation by matrix metalloproteinases. J Biol Chem 270 (1995) 8650-8654
36. Fujinaga K., Onoda K., Yamamoto K., Imanaka-Yoshida K., Takao M., Shimono T., et al. Locally applied cilostazol suppresses neointimal hyperplasia by inhibiting tenascin-C synthesis and smooth muscle cell proliferation in free artery grafts. J Thorac Cardiovasc Surg 128 (2004) 357-363
37. Yamamoto K., Onoda K., Sawada Y., Fujinaga K., Imanaka-Yoshida K., Shimpo H., et al. Tenascin-C is an essential factor for neointimal hyperplasia after aortotomy in mice. Cardiovasc Res 65 (2005) 737-742