Mild serotonin syndrome associated with concurrent linezolid and fluoxetine

American Journal of Health-System Pharmacy

Volumn 64, Issue 1, 2007, Pages 59-62

  Steinberg, Michael ^a   Morin, Anna K ^a  

^a MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

Acyclovir; Antidepressants; Antiinfective agents; Antineoplastic agents; Aztreonam; Drug interactions; Fluoxetine; Linezolid; Lorazepam; Methadone; Nicotine; Quetiapine; Serotonin syndrome; Toxicity; Voriconazole

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ACICLOVIR; AMPHETAMINE; AMPHOTERICIN B DEOXYCHOLATE; ANTIEMETIC AGENT; ANTITUSSIVE AGENT; AZTREONAM; BUSPIRONE; CHLORPROMAZINE; CYPROHEPTADINE; CYTARABINE; DEXTROMETHORPHAN; FLUOXETINE; LEVOFLOXACIN; LINEZOLID; LITHIUM; LORAZEPAM; METHADONE; MONOAMINE OXIDASE INHIBITOR; NICOTINE PATCH; OPIATE; PETHIDINE; PHENYLPROPANOLAMINE; QUETIAPINE; SEROTONIN UPTAKE INHIBITOR; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VANCOMYCIN; VORICONAZOLE;

ABDOMINAL PAIN; ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ANTIBIOTIC RESISTANCE; ARTICLE; BIPOLAR DISORDER; BLOOD CULTURE; CASE REPORT; DEPRESSION; DRUG DOSE INCREASE; DRUG HYPERSENSITIVITY; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEVER; HEPATITIS B; HEPATITIS C; HUMAN; INTRAVENOUS DRUG ABUSE; MALE; MUCOSA INFLAMMATION; NEUTROPENIA; PRIORITY JOURNAL; SEROTONIN SYNDROME;

EID: 33947125982     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.2146/ajhp060227     Document Type: Article

References (8)

1. Zyvox (linezolid) package insert. New York: Pfizer; 2005 Nov.
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7. Thomas CR, Rosenberg M, Blythe V et al. Serotonin syndrome and linezolid. J Am Acad Child Adolesc Psychiatry. 2004; 43:790. Letter.
8. Morales N, Vermette H. Serotonin syndrome associated with linezolid treatment after discontinuation of fluoxetine. Psychosomatics. 2005; 46:274-5. Letter.