Methotrexate-associated lymphoproliferative disorder in a patient with rheumatoid arthritis presenting in the skin

Journal of the American Academy of Dermatology

Volumn 56, Issue 4, 2007, Pages 686-690

  Clarke, Loren E ^a   Junkins Hopkins, Jacqueline ^a   Seykora, John T ^a   Adler, Donald J ^b   Elenitsas, Rosalie ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE;

AGED; ARTICLE; B CELL LYMPHOMA; CASE REPORT; CELL INFILTRATION; CLINICAL FEATURE; DISEASE ASSOCIATION; DISEASE COURSE; EPSTEIN BARR VIRUS; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOREACTIVITY; LYMPHOPROLIFERATIVE DISEASE; NODULATION; PAPULE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

AGED, 80 AND OVER; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BIOPSY, NEEDLE; FACIAL DERMATOSES; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; LONG-TERM CARE; LYMPHOPROLIFERATIVE DISORDERS; METHOTREXATE; RISK ASSESSMENT;

EID: 33947120752     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2006.09.011     Document Type: Article

References (22)

1. Asten P., Barrett J., and Symmons D. Risk of developing certain malignancies is related to duration of immunosuppressive drug exposure in patients with rheumatic diseases. J Rheumatol 26 (1999) 1705-1714
2. Kamel O.W., van de Rijn M., Hanasono M.M., and Warnke R.A. Immunosuppression-associated lymphoproliferative disorders in rheumatic patients. Leuk Lymphoma 16 (1995) 363-368
3. Kamel O.W. Lymphomas during long-term methotrexate therapy. Arch Dermatol 133 (1997) 903-904
4. Kamel O.W. Iatrogenic lymphoproliferative disorders in nontransplantation settings. Semin Diagn Pathol 14 (1997) 27-34
5. Mariette X., Cazals-Hatem D., Warszawki J., Liote F., Balandraud N., and Sibilia J. Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France. Blood 99 (2002) 3909-3915
6. Nelson B.P., Nalesnik M.A., Bahler D.W., Locker J., Fung J.J., and Swerdlow S.H. Epstein-Barr virus-negative post-transplant lymphoproliferative disorders: a distinct entity?. Am J Surg Pathol 24 (2000) 375-385
7. Salloum E., Cooper D.L., Howe G., Lacy J., Tallini G., Crouch J., Schultz M., and Murren J. Spontaneous regression of lymphoproliferative disorders in patients treated with methotrexate for rheumatoid arthritis and other rheumatic diseases. J Clin Oncol 14 (1996) 1943-1949
8. van de Rijn M., and Kamel O.W. Cyclosporine and methotrexate for severe rheumatoid arthritis. N Engl J Med 333 (1995) 1568-1569
9. Thomason R.W., Craig F.E., Banks P.M., Sears D.L., Myerson G.E., and Gulley M.L. Epstein-Barr virus and lymphoproliferation in methotrexate-treated rheumatoid arthritis. Mod Pathol 9 (1996) 261-266
10. Taillan B., Craig F.E., Banks P.M., Sears D.L., Myerson G.E., and Gulley M.L. Lymphoma developing in a patient with rheumatoid arthritis taking methotrexate. Clin Rheumatol 2 (1993) 93-94
11. Sibilia J., Liote F., and Mariette X. Lymphoproliferative disorders in rheumatoid arthritis patients on low-dose methotrexate. Rev Rhum Engl Ed 65 (1998) 267-273
12. Georgescu L., and Paget S.A. Lymphoma in patients with rheumatoid arthritis: what is the evidence of a link with methotrexate?. Drug Saf 20 (1999) 475-487
13. Dawson T.M., Starkebaum G., Wood B.L., Willkens R.F., and Gown A.M. Epstein-Barr virus, methotrexate, and lymphoma in patients with rheumatoid arthritis and primary Sjogren's syndrome: case series. J Rheumatol 28 (2001) 47-53
14. Baecklund E., Askling J., Rosenquist R., Ekbom A., and Klareskog L. Rheumatoid arthritis and malignant lymphomas. Curr Opin Rheumatol 16 (2004) 254-261
15. Verma S., Frambach G.E., Seilstad K.H., Nuovo G., Porcu P., and Magro C.M. Epstein-Barr virus-associated B-cell lymphoma in the setting of iatrogenic immune dysregulation presenting initially in the skin. J Cutan Pathol 32 (2005) 474-483
16. Chai C., White W.L., Shea C.R., and Prieto V.G. Epstein Barr virus-associated lymphoproliferative disorders primarily involving the skin. J Cutan Pathol 26 (1999) 242-247
17. Kamel O.W., Weiss L.M., van de Rijn M., Colby T.V., Kingma D.W., and Jaffe E.S. Hodgkin's disease and lymphoproliferations resembling Hodgkin's disease in patients receiving long-term low-dose methotrexate therapy. Am J Surg Pathol 20 (1996) 1279-1287
18. Harris N.L., and Swerdlow S.H. Methotrexate-associated lymphoproliferative disorders. In: Jaffe E.S., Harris N.L., and Stein H. (Eds). Tumors of hematopoietic and lymphoid tissues (2001), IARC Press, Lyon, France
19. Paul C., Le Tourneau A., Cayuela J.M., Devidas A., Robert C., Molinie V., and Dubertret L. Epstein-Barr virus-associated lymphoproliferative disease during methotrexate therapy for psoriasis. Arch Dermatol 133 (1997) 867-871
20. Kamel O.W., van de Rijn M., LeBrun D.P., Weiss L.M., Warnke R.A., and Dorfman R.F. Lymphoid neoplasms in patients with rheumatoid arthritis and dermatomyositis: frequency of Epstein-Barr virus and other features associated with immunosuppression. Hum Pathol 25 (1994) 638-643
21. Baecklund E., Sundstrom C., Ekbom A., Catrina A.I., Biberfeld P., Feltelius N., and Klareskog L. Lymphoma subtypes in patients with rheumatoid arthritis: increased proportion of diffuse large B cell lymphoma. Arthritis Rheum 48 (2003) 1543-1550
22. Piris M., Brown D.C., Gatter K.C., and Mason D.Y. CD30 expression in non-Hodgkin's lymphoma. Histopathology 17 (1990) 211-218