Maintenance treatment with esomeprazole following initial relief of non-steroidal anti-inflammatory drug-associated upper gastrointestinal symptoms: The NASA2 and SPACE2 studies

Arthritis Research and Therapy

Volumn 9, Issue , 2007, Pages

  Hawkey, Christopher J ^a   Talley, Nicholas J ^b   Scheiman, James M ^c   Jones, Roger H ^d   Långström, Göran ^e   Næsdal, Jorgen ^e   Yeomans, Neville D ^f   Mielants, Herman ^g   Kean, Walter F ^g   Vavrincova ^g   Bolten, Wolfgang W ^g   Buchner, Michael ^g   Habbig, Johannes ^g   Porro, Gabriele Bianchi ^g   Bergmann, Jean François ^g   Philippe, Francis ^g   Demeter, Pal ^g   Bjørneboe, Olav ^g   Kleczkowski, Dariusz ^g   Rudzinski, Janusz ^g   Rovenský, Josef ^g   Halland, Anne ^g   Lanas, Angel ^g   Ung, Kjell Arne ^g   Patel, Atul ^g   more..

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b Mayo Clinic   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e ASTRAZENECA R AND D   (Sweden)

^f UNIVERSITY OF WESTERN SYDNEY   (Australia)

^g NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; ESOMEPRAZOLE; IBUPROFEN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PLACEBO; ROFECOXIB; OMEPRAZOLE;

ABDOMINAL DISCOMFORT; ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CHRONIC DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FREQUENCY ANALYSIS; GASTROENTEROLOGY; GASTROINTESTINAL SYMPTOM; HUMAN; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MEDICAL DOCUMENTATION; MULTICENTER STUDY; OSTEOARTHRITIS; OUTCOMES RESEARCH; PATIENT COMPLIANCE; PRIMARY MEDICAL CARE; RANDOMIZED CONTROLLED TRIAL; RELAPSE; RHEUMATOID ARTHRITIS; RHEUMATOLOGY; SCORING SYSTEM; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; GASTROINTESTINAL DISEASE; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DOUBLE-BLIND METHOD; FEMALE; GASTROINTESTINAL DISEASES; HUMANS; MALE; MIDDLE AGED; OMEPRAZOLE;

EID: 33947106931     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2124     Document Type: Article

References (20)

1. Singh G Ramey DR Morfeld D Shi H Hatoum HT Fries JF Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis. A prospective observational cohort study Arch Intern Med 1996 156 1530-1536 10.1001/archinte.156.14.1530 8687261
2. Straus WL Ofman JJ MacLean C Morton S Berger ML Roth EA Shekelle P Do NSAIDs cause dyspepsia? A meta-analysis evaluating alternative dyspepsia definitions Am J Gastroenterol 2002 97 1951-1958 10.1111/ j.1572-0241.2002.05905.x 12190159
3. Jones RH Tait CL Gastrointestinal side-effects of NSAIDs in the community Br J Clin Pract 1995 49 67-70 7779646
4. Lisse JR Perlman M Johansson G Shoemaker JR Schechtman J Skalky CS Dixon ME Polis AB Mollen AJ Geba GP ADVANTAGE Study Group Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: A randomized, controlled trial Ann Intern Med 2003 139 539-546 14530224
5. Silverstein FE Faich G Goldstein JL Simon LS Pincus T Whelton A Makuch R Eisen G Agrawal NM Stenson WF Gastrointestinal toxicity with celecoxib versus nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid Arthritis: The CLASS study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study JAMA 2000 284 1247-1255 10.1001/jama.284.10.1247 10979111
6. Wiklund I Quality of life in arthritis patients using nonsteroidal anti-inflammatory drugs Can J Gastroenterol 1999 13 129-133 10203431
7. Moayyedi P Braunholtz D Atha P Dowell AC Mason S Axon ATR on behalf of the Leeds HELP study group The influence of dyspepsia, Helicobacter pylori status and irritable bowel syndrome on quality of life in the community [abstract] Gastroenterology 1998 114 4 pt 2 A231
8. Singh G Rosen Ramey D NSAID induced gastrointestinal complications: The ARAMIS perspective - 1997. Arthritis, Rheumatism, and Aging Medical Information System J Rheumatol Suppl 1998 51 8-16 9596549
9. Elliott SL Ferris RJ Giraud AS Cook GA Skeljo MV Yeomans ND Indomethacin damage to rat gastric mucosa is markedly dependent on luminal pH Clin Exp Pharmacol Physiol 1996 23 432-434 8713684
10. Hawkey CJ Karrasch JA Szczepanski L Walker DG Barkun A Swannell AJ Yeomans ND Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group N Engl J Med 1998 338 727-734 10.1056/NEJM199803123381105 9494149
11. Yeomans ND Tulassay Z Juhasz L Racz I Howard JM van Rensburg CJ Swannell AJ Hawkey CJ A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-associated Ulcer Treatment (ASTRONAUT) Study Group N Engl J Med 1998 338 719-726 10.1056/ NEJM199803123381104 9494148
12. Hawkey C Talley NJ Yeomans ND Jones R Sung JJ Langstrom G Naesdal J Scheiman JM NASA1 SPACE1 Study Group Improvements with esomeprazole in patients with upper gastrointestinal symptoms taking non-steroidal antiinflammatory drugs, including selective COX-2 inhibitors Am J Gastroenterol 2005 100 1028-1036 10.1111/j.1572-0241.2005.41465.x 15842575
13. Revicki DA Wood M Wiklund I Crawley J Reliability and validity of the Gastrointestinal Symptom Rating Scale in patients with gastroesophageal reflux disease Qual Life Res 1998 7 75-83 10.1023/A:1008841022998 9481153
14. Wiklund IK Junghard O Grace E Talley NJ Kamm M Veldhuyzen van Zanten S Pare P Chiba N Leddin DS Bigard MA Quality of Life in Reflux and Dyspepsia patients. Psychometric documentation of a new disease-specific questionnaire (QOLRAD) Eur J Surg Suppl 1998 583 41-49 10.1080/ 11024159850191238 10027672
15. Junghard O Lauritsen K Talley NJ Wiklund IK Validation of seven graded diary cards for severity of dyspeptic symptoms in patients with non ulcer dyspepsia Eur J Surg Suppl 1998 583 106-111 10.1080/ 11024159850191355 10027684
16. Bombardier C Laine L Reicin A Shapiro D Burgos-Vargas R Davis B Day R Ferraz MB Hawkey CJ Hochberg MC Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group N Engl J Med 2000 343 1520-1528 10.1056/ NEJM200011233432103 11087881
17. Scheiman JM Yeomans ND Talley NJ Vakil N Chan FK Tulassay Z Rainoldi JL Szczepanski L Ung KA Kleczkowski D Prevention of ulcers by esomeprazole in at-risk patients using non-selective NSAIDs and COX-2 inhibitors Am J Gastroenterol 2006 101 701-710 10.1111/j.1572-0241.2006.00499.x 16494585
18. Bode G Brenner H Adler G Rothenbacher D Dyspeptic symptoms in middle-aged to old adults: The role of Helicobacter pylori infection, and various demographic and lifestyle factors J Intern Med 2002 252 41-47 10.1046/j.1365-2796.2002.01000.x 12074737
19. Talley NJ Evans JM Fleming KC Harmsen WS Zinsmeister AR Melton LJ III Nonsteroidal anti-inflammatory drugs and dyspepsia in the elderly Dig Dis Sci 1995 40 1345-1350 10.1007/BF02065549 7781458
20. Veldhuyzen van Zanten SJ Chiba N Armstrong D Barkun A Thomson A Smyth S Escobedo S Lee J Sinclair P A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in Helicobacter pylori negative, primary care patients with dyspepsia: The CADET-HN Study Am J Gastroenterol 2005 100 1477-188 10.1111/j.1572-0241.2005.40280.x 15984968