QSRR of flavones: Evaluation of substituent contributions to RP HPLC retention

Journal of Liquid Chromatography and Related Technologies

Volumn 30, Issue 8, 2007, Pages 1035-1049

  Stefova, Marina ^a   Stafilov, Trajče ^a   Kulevanova, Svetlana ^b   Stefkov, Gjoshe ^b   Bankova, Vassya S ^c  

^a SS CYRIL AND METHODIUS UNIVERSITY   (Macedonia)

^b SS Cyril and Methodius University Faculty of Pharmacy   (Macedonia)

^c INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

Author keywords

Flavones; Indicator variable; Multiple linear regression; QSRR; Quantitative structure retention relationships; Substituent contribution

Indexed keywords

FLAVORS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LINEAR REGRESSION; NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTIONS;

FLAVONES; INDICATOR VARIABLE; MULTIPLE LINEAR REGRESSION; QUANTITATIVE STRUCTURE-RETENTION RELATIONSHIPS; RETENTION FACTOR; SUBSTITUENT CONTRIBUTION;

KETONES;

CIRSILIOL; FLAVONE DERIVATIVE; TEUCRIUM POLIUM EXTRACT;

ARTICLE; CORRELATION ANALYSIS; DRUG STRUCTURE; MASS SPECTROMETRY; MULTIPLE LINEAR REGRESSION ANALYSIS; NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE RETENTION RELATIONSHIP; REGRESSION ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLUTE; STRUCTURE ACTIVITY RELATION;

TEUCRIUM POLIUM;

EID: 33847782947     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070601128402     Document Type: Article

References (17)

1. Free, S.M., Jr.; Wilson, J.W. A mathematical contribution to structure-activity studies. J. Med. Chem. 1964, 7, 395-399.
2. Molnár, I.; Horváth, C. Catecholamines and related compounds. Effect of substituents on retention in reversed-phase chromatography. J. Chromatogr. 1978, 145, 371-381.
3. Chen, B.K.; Horváth, C. Evaluation of substituent contributions to chromatographic retention: quantitative structure-retention relationships. J. Chromatogr. 1979, 171, 15-28.
4. Gill, R.; Alexander, S.P.; Moffat, A.C. Group-contribution approach to the behaviour of 2-Phenylethylamines in reversed-phase high-performance liquid chromatography. J. Chromatogr. 1981, 218, 639-646.
5. Assenza, S.P.; Brown, P.R. Quantitative structure retention relationships for purine compounds on reversed-phase packings. J. Chromatogr. 1983, 282, 477-486.
6. Sadlej-Sosnowska, N. Structure retention relationship for steroid-hormones-functional-groups as structural descriptors. J. Liq. Chromatogr. 1994, 17, 2319-2330.
7. Smith, R.M. Functional group contributions to the retention of analytes in reversed-phase high-performance liquid chromatogr. J. Chromatogr. A 1993, 656, 381-415.
8. Wollenweber, E.; Dietz, V.H. Occurrence and distribution of free flavonoid aglycones in plants. Phytochemistry 1981, 20, 869-932.
9. Payares, P.; Díaz, D.; Olivero, J.; Vivas, R.; Gómez, I. Prediction of the gas chromatographic relative retention times of flavonoids from molecular structure. J. Chromatogr. A 1997, 771, 213-219.
10. Montaña, M.P.; Pappano, N.B.; Debattista, N.B.; Raba, J.; Luco, J.M. Prediction of the gas chromatographic relative retention times of flavonoids from molecular structure. Chromatographia 2000, 51, 727-35.
11. Stefova, M. PhD Thesis, University Sts Cyril and Methodius, Skopje, 2001.
12. Stefova, M.; Kulevanova, S.; Stafilov, T.; Stefkov, G. Quantitative determination of total flavones in Teucrium polium using HPLC-UV-DAD. Maced. Pharm. Bul. 2003, 49, 184-85.
13. Bankova, V.S.; Popov, S.S.; Marekov, N.L. High-performance liquid chromatographic analysis of flavonoids form propolis. J. Chromatogr. 1982, 242, 135-43.
14. Dondi, F.; Kahie, Y.D.; Lodi, G.; Blo, G.; Pietrogrande, C.; Reschiglian, P. Solvent selectivity effects in reversed-phase high-performance liquid chromatography of flavonoid compounds. J. Chromatogr. 1989, 461, 281-92.
15. 13C NMR spectroscopic data of flavonoid compounds. J. Chromatogr. 1992, 592, 65-73.
16. Mabry, T.J.; Markham, K.R.; Thomas, M.B. The Systematic Identification of Flavonoids; Springer-Verlag: New York-Heidelberg-Berlin, 1970.
17. Zhang, Q.W.; Zhang, Y.X.; Zhang, Y.; Xiao, Y.-Q.; Wang, Z.M. Studies on chemical constituents in buds of Artemisia scoparia. Zhongguo Zhongyao Zazhi 2002, 27 (3), 202-204.